GLYCYRRHIZIN

作品数:33被引量:329H指数:10
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相关作者:楼宜嘉郑芹珠杨会郭远瑾王星更多>>
相关机构:浙江大学华中科技大学荆门市第一人民医院南昌大学更多>>
相关期刊:《Synthetic and Systems Biotechnology》《中国老年学杂志》《中国生物学文摘》《山西医科大学学报》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划河北省自然科学基金更多>>
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Glycyrrhizic acid alleviates lung injury in sepsis through SIRT1/HMGB1 pathway
《BIOCELL》2024年第11期1613-1623,共11页BINGJIE LIN XIAOBO YING CHUANLING ZHANG GUOJUN ZHANG 
supported by the Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project under Grant(No.2023ZL140).
Objectives:This study explores the protective effects of glycyrrhizic acid(GA)on sepsis-induced cellular damage and inflammation in acute lung injury(ALI),specifically through the modulation of the sirtuin 1(SIRT1)and h...
关键词:Glycyrrhizin Acid SEPSIS sirtuin 1(SIRT1) high mobility group box 1(HMGB1) 
高迁移率族蛋白B1抑制剂对白蛋白结合型紫杉醇致神经病理性疼痛的抑制作用及其机制被引量:2
《山西医科大学学报》2022年第9期1120-1126,共7页王力 马莉 贾丽君 周雅卿 赵永林 
国家自然科学基金资助项目(82001327)。
目的探讨高迁移率族蛋白B1(HMGB1)抑制剂Glycyrrhizin(Gly)对白蛋白结合型紫杉醇导致的神经病理性疼痛的抑制作用及其机制。方法雄性SD大鼠共54只,分为对照组、紫杉醇组、紫杉醇+Gly组,每组18只。紫杉醇组大鼠实验第1,3,5,7天腹腔注射...
关键词:HMGB1 神经病理性疼痛 白蛋白结合型紫杉醇 GLYCYRRHIZIN TLR4/NF-κB 神经微丝蛋白 
Glycyrrhizin-Induced Pseudohyperaldosteronism:A Case Report
《Chinese Journal of Integrative Medicine》2022年第7期644-649,共6页FAN Zong-jing LIU Jin-min LI Xing-xing CUI Jie GUO Bin LIN Quan ZHUANG Rui WU Zheng-bo WU Yang 
Supported by National Natural Science Foundation of China (No. 81573900)。
Licorice,also known as Radix Glycyrrhizae,is a natural sweetener and widely used as a drug,and it has been considered to be a healthy natural substance with few side effects.;Pseudo hyperaldosteronism(PsHA),which is c...
关键词:effects. ster ISM 
O-glycosyltransferases from Homo sapiens contributes to the biosynthesis of Glycyrrhetic Acid 3-O-mono-β-D-glucuronide and Glycyrrhizin in Saccharomyces cerevisiae被引量:6
《Synthetic and Systems Biotechnology》2021年第3期173-179,共7页Ke Xu Yu-jia Zhao Nadeem Ahmad Jing-nan Wang Bo Lv Ying Wang Jun Ge Chun Li 
supported by the National Key Research and Development Program of China(2018YFA0901800);the Key Research and Development Program of Hebei Province(21374301D);the Natural Science Foundation of China(No.22078171);the Natural Science Foundation of Hebei Province(No.C2019105055);the Scientific Research Foundation of Tangshan Normal University(No.2021B34).
Glycyrrhizin(GL)and Glycyrrhetic Acid 3-O-mono-β-D-glucuronide(GAMG)are the typical triterpenoid glycosides found in the root of licorice,a popular medicinal plant that exhibits diverse physiological effects and phar...
关键词:O-glycosyltransferase Homo sapiens Glycyrrhizin(GL) Saccharomyces cerevisiae Glycyrrhetic Acid 3-O-mono-β-D-glucuronide(GAMG) 
N-acetylcysteine and glycyrrhizin combination:Benefit outcome in a murine model of acetaminophen-induced liver failure被引量:4
《World Journal of Hepatology》2020年第9期596-618,共23页Charlotte Minsart Sandrine Rorive Arnaud Lemmers Eric Quertinmont Thierry Gustot 
Supported by the Bourse du Conseil Médical de l’hôpital Erasme,Fonds E.et S.Jacobs and Novartis Grant;The CMMI is supported by the European Regional Development Fund and Wallonia
BACKGROUND Acetaminophen overdose is the most frequent cause of drug-induced liver failure in developed countries.Substantial progress has been made in understanding the mechanism of hepatocellular injury,but N-acetyl...
关键词:ACETAMINOPHEN Acute liver injury GLYCYRRHIZIN N-ACETYLCYSTEINE Nacetylcysteine/glycyrrhizin combination Murine model High mobility group box 1 
Pseudo-hyperaldosteronism caused by compound glycyrrhizin tablets: a case report
《Asian Toxicology Research》2020年第2期81-84,共4页Jing Lai Yun-Ying Zhang Qi Zhang 
Compound glycyrrhizin tablets(CGT)is a glycyrrhizin-containing preparation for the treatment of chronic hepatic diseases,it contained Glycyrrhizin,Monoammonium Glycyrrhizinate,Aminoacetic Acid and Methionine.CGT has b...
关键词:Compound GLYCYRRHIZIN tablets Pseudo-hyperaldosteronism Adverse drug reactions 
Immobilization of β-glucuronidase:biocatalysis of glycyrrhizin to 18β-glycyrrhetinic acid and in-silico lead finding
《Journal of Chinese Pharmaceutical Sciences》2020年第5期333-340,共8页Makhmur Ahmad Mohammad Rashid Babar Ali Shamshir Khan Naseem Akhtar Mohd Faiyaz Khan Bibhu Prasad Panda 
The non-covalent immobilization ofβ-glucuronidase enzyme obtained from Rhizopus oryzae was carried out by entrapment in natural fiber(papaya and coconut).The bioconversion capability of immobilized enzyme was analyze...
关键词:18β-Glycyrrhetinic acid GLYCYRRHIZIN Β-GLUCURONIDASE Natural fiber In-silico study 
Berberine attenuates ischemia-reperfusion injury through inhibiting HMGB 1 release and NF-κB nuclear translocation被引量:29
《Acta Pharmacologica Sinica》2018年第11期1706-1715,共10页Jun-rong Zhu Hal-dan Lu Chao Guo Wei-rong Fang Hong-dong Zhao Jun-shan Zhou Feng Wang Yan-li Zhao Yun-man Li Ying-dong Zhang Chang-qing Yang Jian-guo Sun 
Inflammatory damage plays an important role in cerebral ischemic pathogenesis and represents a new target for treatment of stroke. Berberine is a natural medicine with multiple beneficial biological activities. In thi...
关键词:BERBERINE GLYCYRRHIZIN ischemic stroke inflammation HMGB1 TLR4 NF-ΚB 
Influence of compound glycyrrhizin on liver functions, liver fibrosis indexes and inflammatory factors of patients with chronic hepatitis B
《Journal of Hainan Medical University》2017年第4期60-64,共5页Fu-Jiang Peng Tian-Xiao Zhang Mei-Rong Yuan 
Objective:To investigate influence of Compound Glycyrrhizin on liver functions, liver fibrosis indexes and inflammatory factors of patients with chronic hepatitis B.Methods:A total of 96 cases of patients with chronic...
关键词:Compound GLYCYRRHIZIN CHRONIC HEPATITIS B LIVER function LIVER FIBROSIS indexes INFLAMMATORY factors 
HMGR, SQS, β-AS, and Cytochrome P450 Monooxygenase Genes in Glycyrrhiza uralensis被引量:4
《Chinese Herbal Medicines》2015年第4期290-295,共6页Rui Yang Bo-chuan Yuan Yong-sheng Ma Li-qiang Wang Chun-sheng Liu Ying Liu 
Beijing Project for Young Talents(YETP0819);National Science Foundation of China(81503181)
Glycyrrhiza uralensis is frequently used in traditional Chinese medicine. This plant contains a large amount of effective constituents, including triterpenoids and flavonoids. Among them, glycyrrhizin is believed to b...
关键词:β-AS cytochrome P450 monooxygenase functional genes glycyrrhizin HMGR SQS 
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