Supported by Beijing Natural Scientific Foundation(No.7202135);National Natural Science Foundation of China(U1812403-1-1,No.81473315);National Science and Technology Fundamental Resources Investigation Program of China(No.2018FY100701);the Open Research Fund of Chengdu University of Traditional Chinese Medicine Key Laboratory of Systematic Research of Distinctive Chinese Medicine Resources in Southwest China(No.SCMR20210,2021GZ2011003)。
Objective:To investigate the current status and further dtevelopment of Panax genus and6 important individual species including P.notoginseng,P.quinquefolium,P.vietnamensis,P.japonicus,P.stipuleanatus and P.zingiberen...
Supported by National Natural Science Foundation of China(No.81630131,81673633);High-level Talents Research Project of Hefei Normal University(No.2020rcjj30);Key Project of Provincial Scientific Research Platform of Hefei Normal University in 2020(No.2020PTZD14);School Level Quality Engineering Project Of Hefei Normal University(2020szjy10);Undergraduate Innovation and Entrepreneurship Training Program of Hefei Normal University(S202014098050);Key Research and Development Projects of Anhui Province(202004A07020020)。
OBJECTIVE:To elucidate the protective effects of Renshen(Radix Ginseng)and Fuzi(Radix Aconiti Lateralis Preparata)on myocardial infarction(MI)through regulating myocardial autophagy.METHODS:Thirty-one male Sprague-Daw...
the National Natural Science Foundation of China(Grant No.81872996);the State Key Research and Development Project(Grant No.2017YFC1702104);the State Key Project for the Creation of Major New Drugs(2018ZX09711001-009-010);the Tianjin Municipal Education Commission Research Project(Grant No.2017ZD07)。
Inherent complexity of plant metabolites necessitates the use of multi-dimensional information to accomplish comprehensive profiling and confirmative identification.A dimension-enhanced strategy,by offline two-dimensi...
Supported by the National Natural Science Foundation of China(the Study on Intervention and Mechanism of Chinese Herbal Medicines for Nourishing Qi and Resolving Blood Stasis on Cytoskeletal Protein of Vascular Aging(No.81273976);the Mechanism of Exploration about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis in the Prevention and Treatment of Heart Failure through mT ORC1-Mitophagy Pathway(No.8170-3865);Independent Research Program of the China Academy of Chinese Medical Sciences(the Study on Mechanism of Chinese Herbal Medicines for Nourishing Qi and Resolving Blood Stasis Delaying Vascular Aging(No.zz2013002);the Mechanism of Exploration about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis in the Prevention and Treatment of Heart Failure through Nrf2-iron Death Pathway(No.zz13-YQ-034);Beijing Science and Technology Bureau(Clinical study about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis to Improve the Survival Status of Patients with Chronic Heart Failure(No.Z171100001017108)。
OBJECTIVE: To investigate the effects of extracts from Renshen(Radix Ginseng), Sanqi(Radix Notoginseng), and Chuanxiong(Rhizoma Chuanxiong) on the endothelial actin cytoskeleton in senescent human cardiac microvascula...
the grants from the National Natural Science Foundation of China (Nos.81673544 and 81874332);the Fundamental Research Fund of Central South University (No. 2016zzts584);the Teacher-student Innovation and Entrepreneurship Project of Central South University (No.2017gczd028);the Natural Science Foundation of Hunan Province of China (No.2016JJ4113);the Innovation Project for University Students of Hunan Province of China (No.774);the Natural Science Fund for Young Scholars of Xiangya Hospital of Central South University (No.2014Q06).
Cytochromes P450 (CYP450s),a superfamily of mono-oxygenases,are essential to generate highly functionalized secondary metabolites in plants and contribute to the diversification of specialized triterpenoid biosynthesi...
financial support of the key project at the central government level:The Ability Establishment of Sustainable Use for Valuable Chinese Medicine Resources(No.2060302);the Independent Research Grant of National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences(No.ZZXT201608);the National Natural Science Foundation of China(No.81603293)
Soxhlet extraction is a common method of sample preparation. However, there has been no discussion about the efficiency of Soxhlet extraction from different batches and the factors that cause content fluctuation. In t...
supported by the National Natural Science Foundation of China(81773920);the National Basic Research Program of China(973 Program)(2011CB505300,2011CB505302)
Objective:Fuzi Banxia is one of eighteen antagonisms,previous studies have shown that the incompatibility could play special effects in the specific condition of diseases and appropriate compatible environment.The pr...
supported by the National Natural Science Foundation of China(Nos.81303246,81703732);Projects of Priority-Discipline for Colleges and Universities of Jiangsu Province(integration of traditional Chinese and western medicine)
Given the limited studies and conflicting findings, the transport character of ginsenosides crossing the blood-brain barrier (BBB) remains unclear. The present study was designed to qualitatively determine the distr...
supported by the National Natural Science Foundation of China(No.81573789)
Ginsenoside Rh2(Rh2)is one of the major bioactive ginsenosides in Panax ginseng.However,the oral bioavailability of Rh2 is low,with P-glycoprotein(P-gp)and CYP3A4 being reported to be the main factors.The purpose of t...
supported by the National Natural Science Foundation of China,No.81303248,81603321;the Natural Science Foundation of Heilongjiang Province of China,No.H2015028;a grant from the Nursing Program for Young Scholars of Heilongjiang Province of China,No.UNPYSCT-2016116;the Scientific Research Fund for Doctors of Qiqihar Medical University in China,No.QY2016B-09
Kai Xin San is a Chinese herbal formula composed of Radix Ginseng, Poria, Radix Polygalae and Acorus Tatarinowii Rhizome. It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-...