financially supported by Tianjin Municipal Education Commission Research Project(No.2017ZD07)
Shenshao Tablet(SST),prepared from Paeoniae Radix Alba(PRA)and total ginsenoside of Ginseng Stems and Leaves(GSL),is a traditional Chinese medicine(TCM)preparation prescribed to treat coronary heart disease.However,it...
supported by the National Natural Science Foundation of China(Nos.81303246,81703732);Projects of Priority-Discipline for Colleges and Universities of Jiangsu Province(integration of traditional Chinese and western medicine)
Given the limited studies and conflicting findings, the transport character of ginsenosides crossing the blood-brain barrier (BBB) remains unclear. The present study was designed to qualitatively determine the distr...
supported by the National Natural Science Foundation of China(No.81573789)
Ginsenoside Rh2(Rh2)is one of the major bioactive ginsenosides in Panax ginseng.However,the oral bioavailability of Rh2 is low,with P-glycoprotein(P-gp)and CYP3A4 being reported to be the main factors.The purpose of t...
Objective:To investigate the effect of total ginsenoside of ginseng stems and leaves (TGSL) on the pharmacokinetics of aspirin in rats.Methods:Sprague-Dawley rats were randomly divided into two groups (n =6),a combine...
Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We inve...
Medical application of Panax ginseng was first found in "Shen-Nong Herbal Classic" around 200 AD Panax quinquefolium was first introduced in "Essential of Materia Medica" in 1694 in China. The most important bioac...
In the present paper,we overview the discovery of new biological activities induced by ginsenoside Rg1 and Rb1 and discuss possible mechanisms of action. Both compounds could increase neural plasticity in efficacy and...
a grant from the National Natural Science Fundation of China (No. 39470725).
Objective To investigate the protective effects of vitamin B12 , ginseng saponin , and folic acid on mouse embryos subjected to high heat.Methods Mice were used for the experiment.Results After exposure of pregnant mi...
Project supported by Fujian Science and Technology Foundation,№ 2001 Z 037.
AIM: To explore the possible mechanism of the ginsenoside Rgl in protecting substantia nigra neurons from 1-methyl-4-phenyl-l, 2, 3, 6-tetrahydropyridine (MPTP)-induced apoptosis in C57BL mice. METHODS: C57BL male mic...
AIM: To investigate the effect and mechanism of gin-senoside Rg1 on synaptic plasticity of freely moving rats. METHODS: SD rats were chronically implanted with a stimulation electrode in the perfbrant path (PP) of hip...