SPERMATID

作品数：15被引量：38H指数：3
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Three-dimensional reconstruction of rat sperm using volume electron microscopy
《Acta Biochimica et Biophysica Sinica》2024年第11期1699-1705,共7页Jiazheng Liu Limei Lin Lina Zhang Hongtu Ma Xi Chen Keliang Pang Linlin Li Hua Han 
This work was supported by the grants from the STI 2030-Major Projects(Nos.2021ZD0204500,and 2021ZD0204503 to L.L.);the National Natural Science Foundation of China(No.32171461 to H.H.);the Scientific Research Instrument and Equipment Development Project of the Chinese Academy of Sciences(No.YJKYYQ20210022 to H.H.).
Three-dimensional(3D)reconstruction serves as a crucial instrument for the analysis of biological structures.In particular,a comprehensive and accurate 3D ultrastructural examination of rat sperm is vital for understa...
关键词：SPERMIOGENESIS SPERMATID three-dimensional reconstruction ATUM-SEM 
Characterization,expression dynamics,and potential function of OPA1 for regulation of mitochondrial morphology during spermiogenesis in Phascolosoma esculenta
《Journal of Oceanology and Limnology》2024年第1期187-200,共14页Xinming GAO Binbin FENG Chen DU Congcong HOU Shan JIN Daojun TANG Junquan ZHU 
the Ningbo Science and Technology Plan Projects(Nos.2019B10016,2016C10004);the Major Science and Technology Projects in Zhejiang Province(No.2011C12013);the Natural Science Foundation of Zhejiang Province(No.LY18C190007);the Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture,the K.C.Wong Magna Fund in Ningbo University。
Mitochondria undergo morphological changes during spermatogenesis in some animals.The mechanism and role of mitochondrial morphology regulation,however,remain somewhat unclear.In this study,we analyzed the molecular c...
关键词：optic atrophy protein 1(OPA1) SPERMIOGENESIS Phascolosoma esculenta mitochondrial dynamics SPERMATID 
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility被引量：10
《Science China(Life Sciences)》2023年第7期1459-1481,共23页Xin Wang Di-Hang Lin Yue Yan An-Hui Wang Jiaoyang Liao Qian Meng Wen-Qing Yang Heng Zuo Min-Min Hua Fengjuan Zhang Hongwen Zhu Hu Zhou Tian-Yu Huang Rui He Guangyong Li Yue-Qiu Tan Hui-Juan Shi Lan-Tao Gou Dangsheng Li Ligang Wu Yonggang Zheng Xiang-Dong Fu Jinsong Li Rujuan Liu Guo-Hui Li Mo-Fang Liu 
supported by the National Key Research and Development Program of China(2022YFA1303300,2021YFC2700200,2017YFA0504400);Chinese Academy of Sciences(“Strategic Priority Research Program”grants XDB37000000);the National Natural Science Foundation of China(31830109,31821004,91940305,31961133022,32101037,32271347,21933010,22203089);Science and Technology Commission of Shanghai Municipality(17JC1420100,2017SHZDZX01,19JC1410200,21YF1452700,21ZR1470500);the Young Elite Scientist Sponsorship Program of the China Association for Science and Technology(2021QNRC001);the Foundation of Key Laboratory of Gene Engineering of the Ministry of Education。
PIWI-clade proteins harness pi RNAs of 24–33 nt in length.Of great puzzles are how PIWI-clade proteins incorporate pi RNAs of different sizes and whether the size matters to PIWI/pi RNA function.Here we report that a...
关键词：PIWI piRNAs PIWI-Ins translational activation spermatid development male fertility 
BET bromodomain inhibitor JQ1 regulates spermatid development by changing chromatin conformation in mouse spermatogenesis被引量：1
《Genes & Diseases》2022年第4期1062-1073,共12页Xiaorong Wang Mengmeng Sang Shengnan Gong Zhichuan Chen Xi Zhao Guishuan Wang Zhiran Li Yingying Huang Shitao Chen Gangcai Xie Enkui Duan Fei Sun 
This study was supported by the National Key Research and Development Program of China (No. 2018YFC1003500);the National Natural Science Foundation of China (No. 81901528).
As a BET bromodomain inhibitor, JQ1 has been proven have efficacy against a number of different cancers. In terms of male reproduction, JQ1 may be used as a new type of contraceptive, since JQ1 treatment in male mice ...
关键词：Chromatin conformation JQ1 scRNA-seq Spermatid development SPERMATOGENESIS 
Evidence for the role of KIF17 in fish spermatid reshaping:expression pattern of KIF17 in Larimichthys polyactis spermiogenesis被引量：1
《Journal of Oceanology and Limnology》2021年第6期2322-2335,共14页Jingqian WANG Xinming GAO Xuebin ZHENG Chen DU Congcong HOU Qingping XIE Bao LOU Feng LIU Shan JIN Junquan ZHU 
Supported by the NSFC-Zhejiang Joint Fund for the Integration of Industrialization and Informatization(No.U1809212);the Scientific and Technical Project of Zhejiang Province(Nos.2021C02055,2017C02013);the National Natural Science Foundation of China(No.31272642);the Healthy Aquaculture,the K.C.Wong Magna Fund in Ningbo University,and the Collaborative Innovation Center for Zhejiang Marine High-efficiency。
The homodimeric kinesin-2 protein KIF17 functions in intracellular transport and spermiogenesis in mammals.However,its role in fish spermiogenesis has not been reported.Here,we aimed to clone full-length kif17 cDNA an...
关键词：KIF17 SPERMIOGENESIS Larimichthys polyactis spermatid reshaping 
Functional spermatid-like cells derived from the ground-state embryonic stem cells in vitro
《Science China(Life Sciences)》2016年第4期436-437,共2页Yan Zhang Yixun Liu 
Embryonic stem cells（ESCs）are pluripotent and can self-assemble to form cell clusters or embryoid bodies（EBs）,which can then differentiate into all cell types of the three germ layers,as among which one is the pri...
关键词：primordial pluripotent infertility embryonic PGCs maintain transmit founder differentiate methylation 
Putting things in place for fertilization： discovering roles for importin proteins in cell fate and spermatogenesis被引量：3
《Asian Journal of Andrology》2015年第4期537-544,共8页Kate L Loveland Andrew T Major Romaly Butler Julia C Young David A Jan Yoichi Miyamoto 
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus. This vital function must be tightly regulated to cont...
关键词：cell fate cell stress IMPORTIN KARYOPHERIN nucleocytoplasmic transport SPERMATID SPERMATOCYTE SPERMATOGENESIS 
Aquaporins in spermatozoa and testicular germ cells： identification and potential role被引量：4
《Asian Journal of Andrology》2010年第4期490-499,共10页Ching-Hei Yeung 
Mammalian spermatozoa have relatively high water permeability and swell readily, as in the hypo-osmotic swelling test used in the andrology clinic. Physiologically, spermatozoa experience changes in the osmolality of ...
关键词：fertility sperm volume regulation spermatid residual cytoplasm SPERMIOGENESIS water channels 
Immortalized Sertoli cell lines sk11 and sk9 and binding of spermatids in vitro
《Asian Journal of Andrology》2007年第3期312-320,共9页Katja M. Wolski Caroline Feig Christiane Kirchhoff Don F. Cameron 
Aim： To determine the effectiveness of the ski 1, sk9 and ski 1 TNUA5 Sertoli cell lines in binding germ cells in vitro. Methods： The immortalized Sertoli cell lines sk9, ski 1 and ski 1 TNUA5 were used in co-cultur...
关键词：sk Sertoli cells immortalized Sertoli cells Sertoli-germ cell binding Sertoli-germ cell co-culture Sertoli-spermatid junctionalcomplex in vitro cell-cell binding 
Human protamines and the developing spermatid: their structure, function, expression and relationshipwith male infertility被引量：18
《Asian Journal of Andrology》2003年第4期315-324,共10页Vincent W. Aoki Douglas T. Carrell 
During spermiogenesis, the protamine proteins play an integral role in spermatid chromatin compaction. Recent research has focused on many facets of protamine biology, including protamine gene and protein st...
关键词：protamines SPERMATIDS male infertility spermatid transition proteins 
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