Public Welfare Project of Zhejiang Province(Grant no.LGN22C170010 and LGD22C170001)。
In animals,heat stress(HS)disrupts spermatogenesis,reducing sperm quality and,in severe cases,potentially inducing the loss of male reproductive function.Melatonin confers significant resistance to oxidative stress an...
supported by the National Natural Science Foundation of China(32072815);General Project of the Key R&D Plan of Shaanxi Province(2019NY-091);Program of Shaanxi Province Science and Technology Innovation Team(2019TD-036);Fundamental Research Funds for the Central Universities(2452020157)。
Normal spermatogenic processes require the scrotal temperature to be lower than that of the body as excessive heat affects spermatogenesis in the testes,reduces sperm quality and quantity,and even causes infertility.E...
the National Natural Science Foundation of China(Grant No.81871148,No.81701539 and No.81571496).
Varicocele is one of the most important causes of male infertility,as this condition leads to a decline in sperm quality.It is generally believed that the presence of varicocele induces an increase in reactive oxygen ...
This work was supported by the National Key R&D Program of China(No.2018YFC1003701 and No.2017YFC1001402);the National Natural Science Foundation of China(Grant No.31171375).
The transition from spermatogonia to spermatocytes and the initiation of meiosis are key steps in spermatogenesis and are precisely regulated by a plethora of proteins.However,the underlying molecular mechanism remain...
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus. This vital function must be tightly regulated to cont...
The method of laser capture microdissection (LCM) combined with suppressive subtractive hybridization (SSH) was developed to isolate specific germ cells from human testis sections and to identify the genes expressed d...
supported by the Key Project of National Basic Research and Developmental Plan(G2000016103)of China;the National Outstanding Youth Science Foundation(39925027);National Natural Science Foundation of China(39570519);the International Foundation for Science(IFS,B/2425-2F).
Well-spread meiotic pachytene bivalents were obtained by using the prolonged hypotonic treatment com-bined with high chloroform Carnory’s fixative solution from cells of the testes of domestic pigs. Comparison in the...
IT is well known that oocytes, in general condition, can be penetrated by sperm rather thanround spermatids. In 1993, Ogura injected round spermatid nuclei into hamster oocytes anddemonstrated that the spermatid nucle...