The study examines the impact of microstructure and polymethyl methacrylate (PMMA) grafting on the degradability of Zn–Mg alloys. The mechanical properties ofa Zn alloy containing 0.68 wt% Mg and extruded at 200 ◦C a...
Magnesium (Mg) alloys have become a potential material for orthopedic implants due to their unnecessary implant removal, biocompatibility, and mechanical integrity until fracture healing. This study examined the in vi...
This work was supported by National Natural Science Foundation of China[Grant Nos.52122304,52073024 and 51873012];Beijing Outstanding Young Scientist Program[Grant No.BJJWZYJH01201910010024];Chinese Association of Rehabilitation Medicine Technology Development Project[Grant No.KFKT-2022-002].
The infections in open fracture induce high morbidity worldwide.Thus,developing efficient anti-infective orthopedic devices is of great significance.In this work,we designed a kind of infection-responsive long-term an...
This work was supported by Shanghai Sailing Program(22YF1433200);the National Natural Science Foundation of China(82172400).
Implant failure,which is commonly associated with failure of osseointegration and peri-implant infection,is a severe complication of orthopedic surgery.In particular,the survival rate of implants is significantly decr...
supported by the National Institutes of Health[Grant number R01HL140562,R01DK129493 to D.Zhu].
Zinc(Zn)is a new class of bioresorbable metal that has potential for cardiovascular stent material,orthopedic implants,wound closure devices,etc.However,pure Zn is not ideal for these applications due to its low mecha...
funded by the National Key Research and Development Program of China(2018YFE0104200);National Natural Science Foundation of China(51875310,52175274,82172065)and AO Foundation(AOTAP21-47).
Laser powder bed fusion(L-PBF)of magnesium(Mg)alloy porous scaffolds is expected to solve the dual challenges from customized structures and biodegradable functions required for repairing bone defects.However,one of t...
financially supported by The National Key Research and Development Program of China(grant number 2017YFC1104901);The National Natural Science Foundation of China(grant number 51871239,51771227);National Natural Science Foundation of Youth Fund(grant number 51501223).
The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application.Early angiogenesis is important for scaffold survival.It is necessary to develop a multifunctional sur...
the support from the National Natural Science Funds for Distinguished Young Scholar of China(51625404);China Postdoctoral Science Foundation(2018M630909).
In this work,TieMg metal-metal composites(MMCs)were successfully fabricated by spark plasma sintering(SPS).In vitro,the proliferation and differentiation of SaOS-2 cells in response to TieMg metal-metal composites(MMC...
This work was supported by National Natural Science Foundation of China(No.31370954,31670974);Beijing Natural Science Foundation(2164073).
Hydroxyapatite(HA)is an attractive bioceramic for hard tissue repair and regeneration due to its physicochemical similarities to natural apatite.However,its low fracture toughness,poor tensile strength and weak wear r...
Citrate based polymer poly(octamethylene citrate)(POC)has shown promise when formulated into composite material containing up to 65 wt%hydroxylapatite(HA)for orthopedic applications.Despite significant research into P...