SPERMATOGONIA

作品数:30被引量:67H指数:4
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相关领域:生物学医药卫生更多>>
相关机构:华中农业大学南京大学更多>>
相关期刊:《Journal of Integrative Agriculture》《Science Bulletin》《Asian Journal of Andrology》《Aquaculture and Fisheries》更多>>
相关基金:国家自然科学基金广东省自然科学基金山东省自然科学基金国家重点基础研究发展计划更多>>
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A behind-the-scenes role of BDNF in the survival and differentiation of spermatogonia
《Asian Journal of Andrology》2025年第1期37-43,共7页Shin-ichi Tomizawa Kazushige Kuroha Michio Ono Kuniko Nakajima Kazuyuki Ohbo 
partly supported by Grant-in-Aid for Scientific Research on Innovative Areas funding from the Ministry of Education,Culture,Sports,Science,and Technology(MEXT)KAKENHI(No.22H04677 to KO);a grant from the Japan Society for the Promotion of Science KAKENHI(No.20K09543 to ST,No.20K07228 to KK,and No.19KK0183 to KO);the Takeda Science Foundation(2021 to KK).
Mouse spermatogenesis entails the maintenance and self-renewal of spermatogonial stem cells(SSCs),which require a complex web-like signaling network transduced by various cytokines.Although brain-derived neurotrophic ...
关键词:BDNF SPERMATOGENESIS SPERMATOGONIA stem cells 
scRNA-seq reveals that origin recognition complex subunit 6 regulates mouse spermatogonial cell proliferation and apoptosis via activation of Wnt/β-catenin signaling
《Asian Journal of Andrology》2024年第1期46-56,共11页Shi-Wei Liu Jia-Qiang Luo Liang-Yu Zhao Ning-Jing Ou Chao-Yang Yu-Xiang Zhang Hao-Wei Bai Hong-Fang Sun Jian-Xiong Zhang Chen-Cheng Yao Peng Li Ru-Hui Tian Zheng Li Zi-Jue Zhu 
This work was supported by the National Key Research and Development Program of China(No.2022YFC2702700);the National Natural Science Foundation of China(No.82171597);Clinical Research Plan of Shanghai Hospital Development Center(No.SHDC2020CR3077B).
The regulation of spermatogonial proliferation and apoptosis is of great significance for maintaining spermatogenesis.The single-cell RNA sequencing(scRNA-seq)analysis of the testis was performed to identify genes upr...
关键词:cell proliferation ORCG scRNA-seq analysis SPERMATOGONIA Wnt/β-catenin signaling 
Mechanistic target of rapamycin kinase(Mtor)is required for spermatogonial proliferation and differentiation in mice被引量:2
《Asian Journal of Andrology》2020年第2期169-176,共8页Jun Cao Zuo-Bao Lin Ming-Han Tong Yong-Lian Zhang Yi-Ping Li Yu-Chuan Zhou 
This work was supported by the Ministry of Science and Technology of the People’s Republic of China(NO.2014CB943103);the National Natural Science Foundation of China(No.31671203 and NO.31471104);the Science and Technology Commission of Shanghai Municipality(NO.17JC1420100).
Spermatogonial development is a vital prerequisite for spermatogenesis and male fertility.However,the exact mechanisms underlying the behavior of spermatogonia,including spermatogonial stem cell(SSC)self-renewal and s...
关键词:male fertility MICE MTOR SPERMATOGENESIS SPERMATOGONIA TESTIS 
PLZF^posc-KIT^pos-delineated A1-A4-differentiating spermatogonia by subset and stage detection upon Bouin fixation被引量:4
《Asian Journal of Andrology》2019年第3期309-318,共10页Rui-Ling Tang Li-Qing Fan 
the grants from the National Key Research and Development Program of China (Project No. 2016YFC1000200);the National Natural Science Foundation of China (Project No. 31472054).
While hallmarks of rodent spermatogonia stem cell biomarkers' heterogeneity have recently been identified, their stage and subset distributions remain unclear. Furthermore, it is currently difficult to accurately iden...
关键词:asymmetric division cellular homolog of feline sarcoma viral oncogene v-kit false clones GLIAL CELL line-derived NEUROTROPHIC factor receptor alpha 1 PROMYELOCYTIC leukemia zinc finger SPERMATOGONIA stem CELL 
Stimulated by retinoic acid gene 8 (Stra8) plays important roles in many stages of spermatogenesis被引量:6
《Asian Journal of Andrology》2018年第5期479-487,共9页Hai-Tao Ma Chang-Min Niu Jing Xia Xue-Yi Shen Meng-Meng Xia Yan-Qiu Hu Ying Zheng 
This work was supported by the National Natural Science Foundation of China (Number 31371174), the Natural Science Foundation of Jiangsu Province, China (Number BK20131230), and the Postgraduate Research and Practice Innovation Program of Jiangsu Province, China (KYCX17-1893). We thank Dr. Wilkinson (University of California, USA) for kindly providing Rhox 10 antibody.
To clarify the functions and mechanism of stimulated by retinoic acid gene 8 (Stra8) in spermatogenesis, we analyzed the testes from Stra8 knockout and wild-type mice during the first wave of spermatogenesis. Compar...
关键词:differentiation MEIOSIS proliferation SPERMATOGENESIS SPERMATOGONIA Stra8 
Vitamin B12-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration被引量:1
《Asian Journal of Andrology》2017年第5期567-572,共6页Flavia L Beltrame Estela Sasso-Cerri 
The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules. Vitamin ...
关键词:CIMETIDINE FERTILITY SPERMATOGENESIS TESTIS vitamin B12 
Dynamic changes in the expression of apoptosis-related genes in differentiating gonocytes and in seminomas被引量:1
《Asian Journal of Andrology》2015年第3期403-414,共12页Gurpreet Manku 
Apoptosis is an integral part of the spermatogenic process, necessary to maintain a proper ratio of Sertoli to germ cell numbers and provide an adequate microenvironment to germ cells. Apoptosis may also represent a p...
关键词:APOPTOSIS DIFFERENTIATION GONOCYTES seminomas SPERMATOGONIA 
Downregulation of Col lal induces differentiation in mouse spermatogonia被引量:4
《Asian Journal of Andrology》2012年第6期842-849,共8页Sun-Hong Chen Ding Li Chen Xu 
Col la I (one of the subunit of collagen type I) is a collagen, which belongs to a family of extracellular matrix (ECM) proteins that play an important role in cellular proliferation and differentiation. However, ...
关键词:Collal DIFFERENTIATION extracellular matrix (ECM) SPERMATOGENESIS SPERMATOGONIA 
Differentiation of murine male germ cells to spermatozoa n a soft agar culture system被引量:17
《Asian Journal of Andrology》2012年第2期285-293,共9页Mahmoud Abu Elhija Eitan Lunenfeld Stefan Schlatt Mahmoud Huleihel 
Establishment of an in vitro system that allows the development of testicular germ cells to sperm will be valuable for studies of spermatogenesis and future treatments for male infertility. In the present study, we de...
关键词:ACROSOME AGAR in vitro culture MEIOSIS SPERMATOGENESIS SPERMATOGONIA SPERMATOZOA testis 
17beta-estradiol stimulates proliferation of spermatogonia in experimental cryptorchid mice被引量:3
《Asian Journal of Andrology》2007年第5期659-667,共9页En-Zhong Li De-Xue Li Shi-Qing Zhang Chang-Yong Wang Xue-Ming Zhang Jing-Yan Lu Cui-Mi Duan Xiang-Zhong Yang Li-Xin Feng 
Acknowledgment This work was supported by the National Natural Science Foundation of China (No. 30200195). We thank Dr Hai-Bin Wang for taking photographs and Dr Su-Hui Wu (Henan Normal University, China) for statistical analysis. We thank the faculty of Huanghuai University for supporting Dr En-Zhong Li.
Aim: To investigate whether estrogen stimulates the proliferation of spermatogonia or induces spermatogenesis in cryptorchid mice. Methods: Mice were surgically rendered cryptorchid, then treated with different dose...
关键词:17Β-ESTRADIOL cryptorchid mice PROLIFERATION SPERMATOGONIA 
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