ENANTIOSELECTIVE

作品数:269被引量:197H指数:5
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相关领域:理学更多>>
相关作者:夏飞刘秀艳皮超张俊良曾苏更多>>
相关机构:华东师范大学郑州大学南开大学中国科学技术大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Construction of Planar Chiral Ferrocenes by Cobalt-Catalyzed Enantioselective C–H Acyloxylation Enabled by Dual Ligands
《CCS Chemistry》2024年第11期2783-2793,共11页Fan-Rui Huang Peng Zhang Qi-Jun Yao Bing-Feng Shi 
supported by the National Key R&D Program of China(grant nos.2021YFF0701603 and 2022YFA1504302);the National Natural Science Foundation of China(grant nos.21925109,U22A20388,and 92256302);the Fundamental Research Funds for the Central Universities(grant nos.226-2023-00115 and 226-2022-00224);the College of Material Chemistry and Chemical Engineering,Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education,Hangzhou Normal University(grant no.KFJJ2023003).
Oxy-substituted planar chiral ferrocenes are of great importance in asymmetric synthesis and pharmaceuticals.However,enantioselective C–H activation of ferrocenes that form C–O bonds remains a huge challenge and has...
关键词:C–H acyloxylation COBALT dehydrogenative coupling ENANTIOSELECTIVITY FERROCENES 
Research Progress in Enantioselective Radical Desymmetrization Reactions
《CCS Chemistry》2024年第7期1612-1627,共16页Chang-Jiang Yang Lin Liu Qiang-Shuai Gu Xin-Yuan Liu 
Financial support from the National Natural Science Foundation of China (grant nos.22025103,92256301,21831002,22271133,22101122,and 22201127);the National Key R&D Program of China (grant nos.2021YFF0701604 and 2021YFF0701704);New Cornerstone Science Foundation through the XPLORER PRIZE,Shenzhen Science and Technology Program (grant nos.KQTD20210811090112004 and JCYJ20220818100600001);Shenzhen Key Laboratory of Cross-Coupling Reactions (grant no.ZDSYS20220328104200001).
Enantioselective radical desymmetrization is a highly effective approach for rapidly creating enantioenriched molecules,introducing dramatically increased structural complexity from readily available prochiral or meso...
关键词:radical desymmetrization enantioselective desymmetrization radical functionalization transition metal catalysis asymmetric catalysis 
Tunable Unsymmetrical Chiral N-Heterocyclic Carbene Ligands for Highly Diastereo-and Enantioselective Copper-Catalyzed Tandem Borylative Cyclization:Ligand Controlled Diastereoselectivity Reversal被引量:2
《CCS Chemistry》2023年第9期2088-2100,共13页Jiahong Han Yan-Mei He Yixiao Pan Faju Li Dongyu Li Wei Hao Qing-Hua Fan 
the National Key R&D Program of China(grant no.2021YFA1500200);the National Natural Science Foundation of China(grant nos.92056108 and 92256303)for financial support.
A distinct class of C1-symmetric N-heterocyclic carbene(NHC)ligands possessing a chiral fused tetrahydroquinoline ring and a chiral N-arylmethyl group was designed and synthesized via an asymmetric catalytic synthesis...
关键词:N-heterocycliccarbenes asymmetricca-talysis boron copper tandemreaction tetrahy-droquinolines 
General and Modular Access to Enantioenriched α-Trifluoromethyl Ketones via Nickel-Catalyzed Reductive Trifluoroalkylation被引量:2
《CCS Chemistry》2023年第6期1386-1397,共12页Dengkai Lin Yongzhi Chen Zhan Dong Pan Pei Haiting Ji Lanzhu Tai Liang-An Chen 
We gratefully acknowledge funding from the Jiangsu Specially Appointed Professor Plan,National Natural Science Foundation of China(grant no.22071111);Natural Science Foundation of Jiangsu Province of China(grant no.BK20201368).
The development of new catalytic enantioselective access to stereogenic CF_(3)-containingmolecules is of great interest for expediting the discovery of lead compounds that remain challenging.Specifically,enantioselect...
关键词:nickel catalysis ENANTIOSELECTIVE TRIFLUOROMETHYL KETONES RADICAL 
Diastereoselective and Enantioselective Nickel-Catalyzed Reductive Coupling of Imines and Unactivated Alkenes被引量:1
《CCS Chemistry》2023年第4期814-822,共9页Biao Wang Xian-Ming Liu Kai-Xiang Zhang Wei-Min Feng Li-Jun Xiao Qi-Lin Zhou 
the National Natural Science Foundation of China(Nos.21790332,91956000,22188101);the Fundamental Research Funds for the Central Universities,and the Haihe Laboratory of Sustainable Chemical Transformations for their financial support.
Herein we report a method for highly diastereoselective and enantioselective nickel-catalyzed reductive coupling of imines and unactivated alkenes.A monodentate chiral spiro phosphoramidite ligand is the key to contro...
关键词:nickel catalysis ENANTIOSELECTIVE ALKENES IMINES reductive coupling 
Enantioselective Synthesis ofα-Alkenylatedγ-Lactam Enabled by Ni-Catalyzed 1,4-Arylcarbamoylation of 1,3-Dienes被引量:2
《CCS Chemistry》2023年第2期341-349,共9页Feng He Liting Hou Xianqing Wu Haojie Ding Jingping Qu Yifeng Chen 
supported by National Natural Science Foundation of China(grant no.22171079);the Natural Science Foundation of Shanghai(grant no.21ZR1480400);the Shanghai Rising-Star Program(grant no.20QA1402300);the Shanghai Municipal Science and Technology Major Project(grant no.2018SHZDZX03);the Program of Introducing Talents of Discipline to Universities(grant no.B16017);the Fundamental Research Funds for the Central Universities and the China Postdoctoral Science Foundation(grant no.2021M701197).
The facile construction of chiral quaternaryα-alkenylated pyrrolidinones is a long-term challenge in organic synthesis.The asymmetric difunctionalization of 1,3-dienes represents the most compelling tool for assembli...
关键词:LACTAM NICKEL 1 3-diene enantioselective dicarbofunctionalization quaternary stereogenic center 
Chiral Bicyclic Imidazole-Catalyzed Direct Enantioselective C-Acetylation of Indolones
《CCS Chemistry》2023年第2期361-371,共11页Muxing Zhou Yashi Zou Lu Zhang Zhenfeng Zhang Wanbin Zhang 
supported by the National Key R&D Program of China(grant no.2018YFE0126800);the National Natural Science Foundation of China(grant nos.21831005,91856106,21991112,and 22071150);the Shanghai Municipal Education Commission(grant no.201701070002E00030);the China Postdoctoral Science Foundation(grant no.2021M692058).
By adjusting the bond angle and stereocontrol substituent of the chiral bicyclic imidazole catalysts,direct enantioselective C-acetylation of indolones and their sequencial pattern have been successfully developed.Ind...
关键词:ORGANOCATALYSIS Lewis base enantioselective acylation bicyclic imidazole indolone 
Chiral Sulfide/Phosphoric Acid Cocatalyzed Enantioselective Intermolecular Oxysulfenylation of Alkenes with Phenol and Alcohol O-Nucleophiles被引量:2
《CCS Chemistry》2022年第10期3342-3354,共13页Xiao-Dong Liu Yicong Luo Xiaohong Huo Hui-Yun Luo Ren-Fei Cao Zhi-Min Chen 
the National Natural Science Foundation of China(NSFC)(nos.21871178,22071149,21901158,21702135)and the STCSM(no.19JC1430100)for their financial support.
Enantioselective intermolecular three-component oxysulfenylations of alkenes with phenols and alcohols as O-nucleophiles were achieved using chiral BINAM-derived sulfide/phosphoric acid as the cocatalyst.Notably,chira...
关键词:dual catalysis enantioselective sulfenylation three-component reaction O-nucleophile contiguous chiral stereocenter 
Electrochemical Rhodium-Catalyzed Enantioselective C–H Annulation with Alkynes
《CCS Chemistry》2022年第9期3181-3189,共9页Yuan-Qiong Huang Zhi-Jie Wu Li Zhu Qing Gu Xiaojie Lu Shu-Li You Tian-Sheng Mei 
grant fromNSFC(nos.21821002,21772222,and 91956112),CAS(no.XDB20000000);Science and Technology Commission of Shanghai Municipality(nos.18JC1415600 and 20JC1417100).
The synergistic use of transition metal catalysis and electrochemistry is an attractive strategy for oxidative site-selective C–H functionalization since the use of stoichiometric chemical oxidants can be avoided and...
关键词:organic electrochemistry enantioselective C–H annulation rhodium catalysis chiral spiropyrazolones C–H functionalization 
Nickel-Catalyzed Regio-and Enantioselective Hydroarylation of 1,3-Dienes with Indoles
《CCS Chemistry》2022年第8期2612-2619,共8页Lei Cheng Ming-Ming Li Mao-Lin Li Li-Jun Xiao Jian-Hua Xie Qi-Lin Zhou 
the National Natural Science Foundation of China(nos.21790330 and 91956000)and the“111”Project(no.B06005)of the Ministry of Education of China for financial support.
The regio-and enantioselective functionalization of 1,3-dienes has become a powerful tool for the synthesis of allylic compounds,yet it remains a challenge for aliphatic dienes.Herein,we report a nickel-catalyzed asym...
关键词:nickel catalyst aliphatic diene asymmetric hydroarylation chiral indole derivatives C–C bond formation 
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