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作品数:854被引量:1383H指数:17
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相关领域:天文地球医药卫生更多>>
相关作者:黄卫峰乐伟国杨静怡陈建辉孙雅飞更多>>
相关机构:中国科学院解放军理工大学北京外国语大学北京师范大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家科技支撑计划更多>>
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  • 期刊=Neural Regeneration Researchx
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Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease
《Neural Regeneration Research》2025年第10期2982-2997,共16页Hongli Li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng 
financially supported by the National Natural Science Foundation of China,No.823 74552 (to WP);the Science and Technology Innovation Program of Hunan Province,No.2022RC1220 (to WP);the Natural Science Foundation of Hunan Province of China,Nos.2020JJ4803 (to WP),2022JJ40723 (to MY);the Scientific Research Launch Project for New Employees of the Second Xiangya Hospital of Central South University (to MY)
Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut microbiota.The aim of this study was to investigate systemic changes that occur in Alzhei...
关键词:Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis 
Going straight for the gut:gut-brain axis pathology and treatment of Parkinson's disease
《Neural Regeneration Research》2024年第10期2111-2112,共2页Dominique Ebedes Cesar V.Borlongan 
This perspective focuses on the recent literature regarding the role of the gut-brain axis(GBA) in fecal microbiota transplantation(FMT) and stem cell therapy(SCT) in Parkinson's disease(PD).PD is the second most comm...
关键词:STRAIGHT PATHOLOGY PATHOGENESIS 
Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis被引量:3
《Neural Regeneration Research》2024年第10期2281-2289,共9页Wang Liao Jiana Wei Chongxu Liu Haoyu Luo Yuting Ruan Yingren Mai Qun Yu Zhiyu Cao Jiaxin Xu Dong Zheng Zonghai Sheng Xianju Zhou Jun Liu 
supported by the National Natural Science Foundation of China,Nos.82101271 (to WL),82171178 (to JL);Basic and Applied Basic Research Foundation of Guangdong Province,Nos.2020A1515110317 (to WL),2021A1515010705 (to WL);Young Talent Support Project of Guangzhou Association for Science and Technology (to WL);Technology Key Project of Shenzhen,No.JCYJ202001091 14612308 (to ZS)。
Disturbances in the microbiota-gut-brain axis may contribute to the development of Alzheimer's disease. Magnesium-L-threonate has recently been found to have protective effects on learning and memory in aged and Alzhe...
关键词:Alzheimer's disease APP/PS1 double-transgenic Alzheimer's disease mouse model inflammation intestinal barrier dysfunction magnesium-L-threonate microbiome microbiota-gut-brain axis oxidative stress serum metabolites 
Unraveling the gut-brain axis:the impact of steroid hormones and nutrition on Parkinson's disease被引量:3
《Neural Regeneration Research》2024年第10期2219-2228,共10页Paula Maria Neufeld Ralf A.Nettersheim Veronika Matschke Matthias Vorgerd Sarah Stahlke Carsten Theiss 
This comprehensive review explores the intricate relationship between nutrition,the gut microbiome,steroid hormones,and Parkinson's disease within the context of the gut-brain axis.The gut-brain axis plays a pivotal r...
关键词:diet gut-brain axis microbiome neurodegenerative diseases NUTRITION Parkinson's disease PROGESTERONE steroid hormones 
Gut flora in multiple sclerosis:implications for pathogenesis and treatment被引量:2
《Neural Regeneration Research》2024年第7期1480-1488,共9页Weiwei Zhang Ying Wang Mingqin Zhu Kangding Liu Hong-Liang Zhang 
Multiple sclerosis is an inflammatory disorder chara cterized by inflammation,demyelination,and neurodegeneration in the central nervous system.Although current first-line therapies can help manage symptoms and slow d...
关键词:gut flora gut-brain axis multiple sclerosis PATHOGENESIS treatment 
Immune regulation of the gut-brain axis and lung-brain axis involved in ischemic stroke被引量:8
《Neural Regeneration Research》2024年第3期519-528,共10页Xiaodi Xie Lei Wang Shanshan Dong ShanChun Ge Ting Zhu 
supported by the National Natural Science Foundation of China,No.82204663;the Natural Science Foundation of Shandong Province,No.ZR2022QH058(both to TZ).
Local ischemia often causes a series of inflammatory reactions when both brain immune cells and the peripheral immune response are activated.In the human body,the gut and lung are regarded as the key reactional target...
关键词:enteric glia cells gut microbiota gut-brain axis immune response inflammation ischemic stroke lung-brain axis microglia 
Saliva:a challenging human fluid to diagnose brain disorders with a focus on Alzheimer's disease被引量:3
《Neural Regeneration Research》2023年第12期2606-2610,共5页Christine Zürcher Christian Humpel 
Biomarkers are molecules of biological processes that help in both the diagnosis of human diseases and in follow-up assessments of therapeutic responses. Biomarkers can be measured in many human fluids, such as blood,...
关键词:Alzheimer's disease biomarkers diagnosis oral-gut-brain axis PERIODONTITIS SALIVA 
Gut-brain axis:does intestinal inflammation affect hippocampal neurogenesis and medulloblastoma development?
《Neural Regeneration Research》2023年第11期2381-2382,共2页Arianna Casciati Mariateresa Mancuso Roberta Vitali Simonetta Pazzaglia 
NANOCROSS project"Plant virus nanoparticles for blood-brain barrier crossing and medulloblastoma targeting"granted by the Italian Association for Cancer Research:IG 20314 to MM。
Gut-brain axis:does intestinal inflammation affect hippocampal neurogenesis and medulloblastoma development?Inflammatory bowel diseases (IBD) are a group of disorders that cause chronic inflammation in the intestines,...
关键词:inflammation DISEASES continuously 
Gut-brain axis in traumatic brain injury: impact on neuroinflammation被引量:3
《Neural Regeneration Research》2022年第5期1007-1008,共2页Marta Celorrio Stuart H.Friess 
supported by NIH R01-NS097721。
The gastrointestinal track is inhabited by tens of trillions of microorganisms. The gut microbiota is involved in gut motility, nutrient absorption and synthesis of metabolites that influence hmeostasis, metabolism an...
关键词:METABOLISM inflammation STASIS 
Whole-brain three-dimensional imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases
《Neural Regeneration Research》2020年第12期2255-2257,共3页Henrik HHansen Urmas Roostalu Jacob Hecksher-Sorensen 
Quantitative histopathology in preclinical neuroscience:Altered brain functionality in neurodegenerative diseases,including Parkinson’s disease(PD)and Alzheimer’s disease(AD),involve complex pathological changes and...
关键词:DRUG TREATMENT ALZHEIMER 
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