supported by the National Natural Science Foundation of China,Nos.82271257(to YZ)and 82071228(to YZ);Qing Lan Project(to YZ);Open Competition Grant of Xuzhou Medical University(to YZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.KYCX21_2705(to TS)。
Microglia-mediated neuroinflammation is considered a pathological feature of Parkinson's disease.Triggering receptor expressed on myeloid cell-1(TREM-1)can amplify the inherent immune response,and crucially,regulate i...
supported by the National Natural Science Foundation of China,No. 81771327 (to BYL);Construction of Central Nervous System Injury Basic Science and Clinical Translational Research Platform;Budget of Beijing Municipal Health Commission 2020, No. PXM2020_026280_000002 (BYL)。
After brain injury, infiltration and abnormal activation of neutrophils damages brain tissue and worsens inflammation, but the mediators that connect activated neutrophils with neuroinflammation have not yet been full...
supported by the National Natural Science Foundation of China,No.81771297(to YNZ);CuiYing Scientific and Technological Innovation Program of Lanzhou University Second Hospital of China,No.CY2017-MS04(to YNZ);Hui-Chun Chin and Tsung-Dao Lee Chinese Undergraduate Research Endowment of China,No.LZU-JZH2224(to YCW);National Innovation and Entrepreneurship Training Program for Undergraduate of China,No.201910730212(to YCW);CuiYing Scientific Training Program for Undergraduates of Lanzhou University Second Hospital of China,No.CYXZ2019-06(to YCW).
Myeloperoxidase is an important inflammatory factor in the myeloid system,primarily expressed in neutrophils and microglia.Myeloperoxidase and its active products participate in the occurrence and development of hemor...
supported by the Science and Technology Bureau Fund of Sichuan Province of China,No.2020YFS0220;the China Postdoctoral Science Foundation,No.2019M653427;Postdoctoral Research Project,West China Hospital,Sichuan University of China,No.2019HXBH029;Health Commission of Sichuan Province of China,No.20PJ038(all to QQW)。
The neutrophil-to-lymphocyte ratio(NLR)is considered a robust prognostic biomarker for predicting patient survival outcomes in many diseases.However,it remains unclear whether it can be used as a biomarker for amyotro...