From the outside,the dusty,maroon-colored Huaqing Commercial Building looks just JL.like any other Chinese office building built in the early 2000s.What it truly is,however,is an entertainment hub nestled in the heart...
supported by ANID Fondecyt Iniciacion 11180540(to FJB);ANID PAI 77180077(to FJB);UNAB DI-02-22/REG(to FJB);Exploración-ANID 13220203(to FJB);ANID-MILENIO(NCN2023_23,to FJB)。
Since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully a...
National Key Basic Research and Development Program of China(2019YFA0801402,2018YFA0107200,2018YFA0801402,2018YFA0800100);Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020501,XDA16020404);National Natural Science Foundation of China(32130030,31900454).
Continuous immunosuppression has been widely used in xenografts into non-human primate brains.However,how immune responses change after transplantation in host brains under continuous immunosuppressive adminis-tration...
supported by SKLID Development Grants(2021SKLID504,2019SKLID401,2019SKLID603,and 2016SKLID603);the National Natural Science Foundation of China(81772197,81401670,and 81630062)。
Objective To analyze the relationship between Chemokine IP10 and its receptor CXCR3 during prion infection.Methods We investigated the increases in IP10 signals,primarily localized in neurons within the brains of scra...
To create autonomous robots,both hardware and software are needed.If enormous progress has already been made in the field of equipment,then robot software depends on the development of artificial intelligence.This art...
The publisher regrets to note that reference citation errors have occurred in panels b,c,e-l in Fig 2 and the sentence“However,the literature reports both decreased and increased intra-network functional connections ...
Mucosal-associated lymphoid tissues are the immune structures that rapidly initiate local immune responses;the dura mater is the outermost layer of the meninges covering and connecting central nervous system(CNS)with ...
Objective To analyze the differential genes and related signaling pathways of microglia subpopulations in Parkinson's disease (PD)-like mouse brains induced by paraquat (PQ) based on single-cell RNA sequencing,and pro...
In October 2023,a set of 21 papers published simultaneously in the journals Science,Science Advances,and Science Translational Medicine reported the largest,most-detailed maps to date of the cells making up portions o...
Support for N.S.C.and L.M.B.provided by the Huntington’s Disease Society of America Berman/Topper HD Career Development Fellowship.Project operational support for E.J.W.,B.R.L.,and M.R.H.provided by F.Hoffmann-La Roche.Additional operational support for N.S.C.and M.R.H.provided by a Bev Hartig Huntington’s Disease Foundation grant.Funding sources were not involved in the design of experiments,collection and measurement of samples,or analysis and interpretation of the data presented herein.
Background Therapeutic approaches aimed at lowering toxic mutant huntingtin(mHTT)levels in the brain can reverse disease phenotypes in animal models of Huntington’s disease(HD)and are currently being evaluated in cli...