DECELLULARIZATION

作品数：41被引量：126H指数：5
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相关领域：医药卫生更多>>
相关作者：陈晓波更多>>
相关机构：首都医科大学第二军医大学浙江大学医学院附属邵逸夫医院南方医科大学更多>>
相关期刊：《Journal of Life Sciences》《Cell Regeneration》《Science China(Life Sciences)》《World Journal of Experimental Medicine》更多>>
相关基金：国家自然科学基金中国博士后科学基金国家高技术研究发展计划北京市自然科学基金更多>>
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Determination of DNA content as quality control in decellularized tissues:challenges and pitfalls
《Regenerative Biomaterials》2025年第1期170-177,共8页Charlot Philips Lisanne Terrie Ewout Muylle Lieven Thorrez 
supported by the Research Foundation—Flanders[G0D3620N and 1133520N]。
Decellularized organs and tissues are emerging within the field ofregenerative medicine to meet the growing demand for organand tissue transplantation. Quality control of these acellular matrices prior to transplantat...
关键词：DECELLULARIZATION skeletal muscle DNA quantification SPECTROPHOTOMETER 
Perspectives on the extracellular matrix in inflammatory bowel disease and bowel decellularization protocols
《World Journal of Experimental Medicine》2024年第4期86-95,共10页Caroline Bures de Paulo Maria Angelica Miglino Patricia Castelucci 
Supported by São Paulo Research Foundation(Fundação de AmparoàPesquisa do Estado de São Paulo-FAPESP,Brazil),No.2014/25927-2,No.2018/07862-1,No.2021/05445-7,and No.2022/00086-1;the Brazilian National Council for Scientific and Technological Development(Conselho Nacional de Desenvolvimento Científico e Tecnológico-CNPq,Brazil);and the Brazilian Federal Agency for Support and Evaluation of Graduate Education(Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-CAPES,Brazil).
The extracellular matrix(ECM)is a non-cellular three-dimensional structure present in all tissues that is essential for the intestinal maintenance,function and structure,as well as for providing physical support for t...
关键词：Extracellular matrix Inflammatory bowel disease Decellularization protocols Regenerative medicine INTESTINE 
Acellular dermal matrices in reconstructive surgery;history,current implications and future perspectives for surgeons
《World Journal of Clinical Cases》2024年第35期6791-6807,共17页Ömer F Dilek Kamuran Z Sevim Osman N Dilek 
Large-scale defects of body in the reconstructive surgical practice,and the help-lessness of their repair with autologous tissues,have been an important factor in the development of artificial biological products for ...
关键词：Acellular dermal matrices BREAST DECELLULARIZATION Reconstruction Surgery Tissue defect 
Biomaterial engineering strategies for modeling the Bruch's membrane in age-related macular degeneration
《Neural Regeneration Research》2024年第12期2626-2636,共11页Blanca Molins Andrea Rodríguez Víctor Llorenç Alfredo Adán 
supported by the Ministry of Science and Innovation of Spain,"Instituto de Salud CarlosⅢ","Fon do de Investigacion Sanitaria" (PI19/00265);funds FEDER"Una manera de hacer Europa" (to BM)。
Age-related macular degeneration,a multifactorial inflammatory degenerative retinal disease,ranks as the leading cause of blindness in the elderly.Strikingly,there is a scarcity of curative therapies,especially for th...
关键词：age-related macular degeneration Bruch's membrane DECELLULARIZATION retinal pigment epithelium SCAFFOLD 
Liver tissue engineering using decellularized scaffolds:Current progress,challenges,and opportunities
《Bioactive Materials》2024年第10期280-305,共26页Kamal H.Hussein Boyukkhanim Ahmadzada Julio Cisneros Correa Ahmer Sultan Silvana Wilken Bruce Amiot Scott L.Nyberg 
support from the Fulbright Visiting Scholar Program(2023-2024).
Liver transplantation represents the only definitive treatment for patients with end-stage liver disease.However,the shortage of liver donors provokes a dramatic gap between available grafts and patients on the waitin...
关键词：Bioengineered liver DECELLULARIZATION Recellularization REENDOTHELIALIZATION Biliary reconstruction 
High quality repair of osteochondral defects in rats using the extracellular matrix of antler stem cells被引量：1
《World Journal of Stem Cells》2024年第2期176-190,共15页Yu-Su Wang Wen-Hui Chu Jing-Jie Zhai Wen-Ying Wang Zhong-Mei He Quan-Min Zhao Chun-Yi Li 
National Natural Science Foundation of China,No.U20A20403;This study was conducted in accordance with the Animal Ethics Committee of the Institute of Antler Science and Product Technology,Changchun Sci-Tech University(AEC No:CKARI202309).
BACKGROUND Cartilage defects are some of the most common causes of arthritis.Cartilage lesions caused by inflammation,trauma or degenerative disease normally result in osteochondral defects.Previous studies have shown...
关键词：Osteochondral defect repair Mesenchymal stem cells Extracellular matrix DECELLULARIZATION Antler stem cells Reserve mesenchymal cells Xenogeneic 
Mechanisms underlying the cell-matrixed nerve grafts repairing peripheral nerve defects被引量：1
《Bioactive Materials》2024年第1期563-577,共15页Shanshan Wang Hongkui Wang Panjian Lu Leilei Gong Xiaosong Gu Meiyuan Li 
supported by grants from the National Natural Science Foundation of China(Grant No.32130060,31730031 and 81901256);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
Decellularized extracellular matrix(dECM),with its distinct biological properties,has gained significant attention as a natural biomaterial.Leveraging its potentials,we successfully developed a three-dimensional matri...
关键词：DECELLULARIZATION Extracellular matrix hBMSC Peripheral nerve regeneration Tissue engineering 
Decellularized extracellular matrix:A promising strategy for skin repair and regeneration被引量：5
《Engineered Regeneration》2023年第4期357-374,共18页Shengjie Jiang Yu Zhuang Ming Cai Xudong Wang Kaili Lin 
funded by the National Natural Science Foundation of China(Grant Nos.82072396,32271379);Science and Technology Commission of Shanghai Municipality(21490711700);the Interdisciplinary Program of Shanghai Jiao Tong University(YG2021ZD12).
The skin is an important organ of the human body that resists external threats but lacks sufficient self-regeneration ability when severe damage occurs.However,most of the available skin substitutes cannot achieve ide...
关键词：DECELLULARIZATION Extracellular matrix Skin regeneration Biomaterial Bioink 
Polyethylene glycol crosslinked decellularized single liver lobe scaffolds with vascular endothelial growth factor promotes angiogenesis in vivo被引量：1
《Hepatobiliary & Pancreatic Diseases International》2023年第6期622-631,共10页Jian-Se Zhang Zhi-Bin Wang Zhi-Zhen Lai Jing-Wen Yang Wen-Jing Song Yu-Bing Wei Jin Mei Jian-Guang Wang 
supported by grants from Natural Science Foundation of Zhejiang Province (LY20H180011);National Natural Science Foundation of China (81970653);Medical and Health Science and Technology project of Zhejiang (2016KYA061)
Background: Improving the mechanical properties and angiogenesis of acellular scaffolds before transplantation is an important challenge facing the development of acellular liver grafts. The present study aimed to eva...
关键词：DECELLULARIZATION Single liver lobe Polyethylene glycol ANGIOGENESIS Liver tissue engineering 
Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea被引量：1
《Bioactive Materials》2023年第11期265-278,共14页Yansha Hao Jingting Zhou Ju Tan Feng Xiang Zhongliang Qin Jun Yao Gang Li Mingcan Yang Lingqin Zeng Wen Zeng Chuhong Zhu 
National Science Fund for Distinguished Young Scholars(No.31625011);the National Key Research and Development Program(No.2016YFC1101100).
Cross-linking agents are frequently used to restore corneal properties after decellularization,and it is especially important to select an appropriate method to avoid excessive cross-linking.In addition,how to promote...
关键词：DECELLULARIZATION Bioartificial cornea Cross-linking BIOCOMPATIBILITY TRANSPARENCY 
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