SULFOTRANSFERASES

作品数：5被引量：11H指数：2
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相关领域：医药卫生更多>>
相关作者：冀希炜李健王思媛邵雪岩周田彦更多>>
相关机构：北京大学更多>>
相关期刊：《Journal of Chinese Pharmaceutical Sciences》《Acta Pharmacologica Sinica》《Virologica Sinica》《Signal Transduction and Targeted Therapy》更多>>
相关基金：国家自然科学基金更多>>
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Genome mining of sulfonated lanthipeptides reveals unique cyclic peptide sulfotransferases
《Acta Pharmaceutica Sinica B》2024年第6期2773-2785,共13页Meng Wang Wen-Wei Li Zhe Cao Jianong Sun Jiang Xiong Si-Qin Tao Tinghong Lv Kun Gao Shangwen Luo Shi-Hui Dong 
supported by the National Natural Science Foundation of China(No.21907047,22077056,and 21907046);the Fundamental Research Funds for the Central Universities(No.lzujbky2019-ct03,lzujbky-2019-10,and lzujbky-2021-ct05,China).
Although sulfonation plays crucial roles in various biological processes and is frequently utilized in medicinal chemistry to improve water solubility and chemical diversity of drug leads,it is rare and underexplored ...
关键词：Lanthipeptides SULFOTRANSFERASES SULFONATION BIOSYNTHESIS Genome mining 
SARS-CoV-2 spike protein-ACE2 interaction increases carbohydrate sulfotransferases and reduces N-acetylgalactosamine-4-sulfatase by p38 MAPK
《Signal Transduction and Targeted Therapy》2024年第3期1174-1185,共12页Sumit Bhattacharyya Joanne K.Tobacman 
Immunostaining in lungs of patients who died with CovID-19 infection showed increased intensity and distribution of chondroitin sulfate and decline in N-acetylgalactostamine-4-sulfatase(Arylsulfatase B;ARSB).To explai...
关键词：ACE2 lung inhibited 
Osthole prevents acetaminophen-induced liver injury in mice被引量：8
《Acta Pharmacologica Sinica》2018年第1期74-84,共11页Yun CAI Wu SUN Xin-xin ZHANG Yan-die LIN Hao CHEN Hao LI 
This study was supported by the National Natural Science Foundation of China （No 81270944 and 81070678） and the Qinglan Project （2014） awarded to Dr Hao LI. Dr Hao LI is an associate fellow at the Collaborative Innovation Center for Cardiovascular Disease Translational Medicine.
Acetaminophen （APAP） overdose leads to severe hepatotoxicity. Osthole, a natural coumarin found in traditional Chinese medicinal herbs, has therapeutic potential in the treatment of various diseases. In this study, ...
关键词：ACETAMINOPHEN HEPATOTOXICITY OSTHOLE oxidative stress inflammatory cytokines UDP-GLUCURONOSYLTRANSFERASES SULFOTRANSFERASES H89 L-buthionine sulfoximine 
Comparison of dopamine with levodopa in the induction of aryl sulfotransferases and estrogen sulfotransferase in rat liver
《Journal of Chinese Pharmaceutical Sciences》2014年第7期471-479,共9页邵雪岩 李健 王思媛 陈广平 许娇娇 冀希炜 李良 卢炜 周田彦 
National Natural Science Foundation of China(Grant No.81072699)
Sulfotransferases（SULTs） are one of the most important phase II drug-metabolizing enzymes. Among them, aryl sulfotransferases（SULT1A1） and estrogen sulfotransferase（EST, SULT1E1） belong to the rSULT1 family that...
关键词：DOPAMINE LEVODOPA Dopamine receptors SULFOTRANSFERASE INDUCTION 
The Importance of Heparan Sulfate in Herpesvirus Infection被引量：3
《Virologica Sinica》2008年第6期383-393,共11页Christopher D. O'Donnell Deepak Shukla 
NIH grant (AI 057860 to D.S)
Herpes simplex virus type-1 (HSV-1) is one of many pathogens that use the cell surface glycosaminoglycan heparan sulfate as a receptor. Heparan sulfate is highly expressed on the surface and extracellular matrix of vi...
关键词：Heparan sulfate （HS） HERPESVIRUSES Herpes simplex virus type-1 （HSV-1） 3-O-sulfotransferases Viral entry 
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