Background:To investigate SCL/TAL 1 interrupting locus(STIL)’s role and prognostic significance in lung adenocarcinoma(LUAD)progression,we examined STIL and E2 promoter binding factor 1(E2F1)expression and their impa...
National Key R&D Program of China(2021YFA1300403 and 2019YFA0906300);Youth Innovation Promotion Association of CAS(2020081);CAS Interdisciplinary Innovation Team(JCTD-2020-06);CAS Project for Young Scientists in Basic Research(YSBR-004);National Natural Science Foundation of China(32222007);Innovation Platform for Academicians of Hainan Province(2022YSCXTD0005);Science&Technology Specific Project in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta(2022SZX12).
Diatoms,a group of prevalent marine algae,contribute significantly to global primary productivity.Their substantial biomass is linked to enhanced absorption of blue-green light underwater,facilitated by fucoxanthin ch...
Plant-specific transcriptional regulators called TELOMERE REPEAT BINDING proteins(TRBs)combine two DNA-binding domains,the GH1 domain,which binds to linker DNA and is shared with H1 histones,and the Myb/SANT domain,wh...
supported by Beijing Municipal Natural Science Foundation(China)(No.7192084);The Capital Health Research and Development of Special(China)(No.2020-2-1152);Beijing Municipal Institute of Public Medical Research Development and Reform Pilot Project(China)(No.Jingyiyan 2019-6);National Natural Science Foundation of China(No.81672026);Research and demonstration application of clinical diagnosis and treatment technology in the capital(China)(No.Z191100006619064).
Malignant tumor is still a major problem worldwide.During tumorigenesis or tumor development,tumor suppressor p53-binding protein 2(TP53BP2),also known as apoptosis stimulating protein 2 of p53(ASPP2),plays a critical...
funded by the National Natural Science Foundation of China(No.31971682);the Research Startup Fund for High-Level and High-Educated Talents of Nanjing Forestry University.
Low temperature stress is one of the most important factors limiting plant growth and geographical distribution.In order to adapt to low temperature,plants have evolved strategies to acquire cold tolerance,known as,co...
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Science(XDA16020400 to P.H.);Ministry of Science and Technology of China(2017YFA0102700 to P.H.);the National Natural Science Foundation of China(32170804 to P.H.and 81200355 to W.Y.);CAS-Youth Innovation Program Association(2016246 to W.Y.);Shanghai Natural Science Foundation(18ZR1446300 to W.Y.).
Long non-coding(lnc)RNA plays important roles in many cellular processes.The function of the vast majority of lncRNAs remains unknown.Here we identified that lncRNA-1700113A16RIK existed in skeletal muscle stem cells(...
supported by the grants from the National Key Research and Development Program of China(No.2016YFA0500600);the National Natural Science Foundation of China(Nos.31900112,21907065,31970130,and 31670831);Anhui Provincial Natural Science Foundation(No.2108085QH380);Grants for Scientific Research from Anhui Medical University(Nos.0601094201 and 2021xkj012).
Type 2 diabetes mellitus(T2DM)is recognized as a serious public health concern with increasing incidence.The dipeptidyl peptidase-4(DPP-4)inhibitor sitagliptin has been used for the treatment of T2DM worldwide.Althoug...
Objective To evaluate the efficacy and prognostic factors in core binding factor (CBF) acute myeloid leukemia (AML) under current therapy modalities,therefore optimizing the treatment strategies.Methods Standard cytol...