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miR-29a up-regulation in AR42J cells contributes to apoptosis via targeting TNFRSF1A gene被引量：7
《World Journal of Gastroenterology》2016年第20期4881-4890,共10页Qiang Fu Tao Qin Lin Chen Chuan-Jiang Liu Xu Zhang Yu-Zhu Wang Ming-Xing Hu Hao-Yuan Chu Hong-Wei Zhang 
AIM: To investigate the expression of mi R-29 a in rat acute pancreatitis and its functional role in AR42 J cell apoptosis.METHODS: Twelve SD rats were divided into a control group and an acute edematous pancreatitis(...
关键词：Acute EDEMATOUS PANCREATITIS mi R-29a APOPTOSIS AR42J Target GENE TNFRSF1A 
Up-regulation of micro RNA-210 inhibits proliferation of hepatocellular carcinoma cells by targeting YES1被引量：4
《World Journal of Gastroenterology》2015年第46期13030-13041,共12页Weiqi Tan Seng-Gee Lim Theresa MC Tan 
Supported by Biomedical Research Council and Ministry of Education(Tier 1)awarded to Tan TM
AIM: To determine the expression of micro RNA-210(mi R-210) in hepatocellular carcinoma(HCC) and to examine its role using HCC cells.METHODS: The expression of mi R-210 was determined in 21 pairs of HCC samples and th...
关键词：Micro RNA-210 HEPATOCELLULAR CARCINOMA Proliferati 
Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling被引量：14
《World Journal of Gastroenterology》2015年第23期7197-7207,共11页Yong-Bin Zheng Gao-Chun Xiao Shi-Lun Tong Yu Ding Qiu-Shuang Wang Sheng-Bo Li Zhi-Nan Hao 
Supported by National Natural Science Foundation of China,No.81372553
AIM: To examine the potential anti-tumor activity of paeoniflorin in the human gastric carcinoma cell line MGC-803.METHODS: Cell viability and cytotoxic effects in MGC-803 cells were analyzed using a 3-(4,5-dimethylth...
关键词：Gastric cancer PAEONIFLORIN MicroRNA-124 PHOSPHATIDYLINOSITOL 3-kinase Akt Signal transducerand ACTIVATOR of transcription 3 
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer被引量：9
《World Journal of Gastroenterology》2014年第45期17037-17048,共12页Ru Chen Sheng Pan Keith Lai Lisa A Lai David A Crispin Mary P Bronner Teresa A Brentnall 
Supported by Grants from National Institutes of Health,No.R21CA164548;from Crohn’s and Colitis Foundation of America
AIM: To characterize tumor necrosis factor receptor-associated protein 1 (TRAP1) expression in the progression of ulcerative colitis (UC)-associated colorectal cancer.
关键词：Ulcerative colitis Colorectal cancer Inflammation Oxidative stress Tumor necrosis factor receptor-associated protein 1 
Hyperoxia accelerates progression of hepatic fibrosis by up-regulation of transforming growth factor-β expression被引量：6
《World Journal of Gastroenterology》2014年第11期3011-3017,共7页Sang Hwa Lee Sung-Im Do Hyun-Soo Kim 
Supported by Aerospace Medicine Research Project funded by the Medical Division,Headquarter,Republic of Korea Air Force(2012)
AIM: To investigate the effect of hypoxia or hyperoxia on the progression of hepatic fibrosis and to examine the role of transforming growth factor-β (TGF-β) in the livers of rats exposed to hypoxic or...
关键词：Hepatic fibrosis  Cirrhosis  Hypoxia  Hyperoxia  Transforming growth factor-β 
Cytokeratin 8 is increased in hepatitis C virus cells and its ectopic expression induces apoptosis of SMMC7721 cells被引量：3
《World Journal of Gastroenterology》2013年第37期6178-6187,共10页Ming-Zhu Sun Shuang-Suo Dang Wen-Jun Wang Xiao-Li Jia Song Zhai Xin Zhang Mei Li Ya-Ping Li Meng Xun 
Supported by National Natural Science Foundation of China,No.81170393
AIM:To investigate cytokeratin 8(CK8)overexpression during hepatitis C virus(HCV)infection and its pathogenesis,and the effect of ectopic CK8 expression on hepatoma cell lines.METHODS:We successfully established an in...
关键词：HEPATITIS C virus cell culture system Cytoker-atin 8 UP-REGULATION EUKARYOTIC expression APOPTOSIS 
Influence of up-regulation of Notch ligand DLL4 on biological behaviors of human gastric cancer cells被引量：12
《World Journal of Gastroenterology》2013年第28期4486-4494,共9页Guo-Gang Li Lan Li Chao Li Long-Yun Ye Xiao-Wen Li Da-Ren Liu Qi Bao Yi-Xiong Zheng Da-Peng Xiang Li Chen Jian Chen 
Supported by The Key Project of Science and Technology of Zhejiang Province, No. 2009C14017;the National Natural Science Foundation of China, No. 81071959 and No. 81101837;the Zhejiang Provincial Medical and Healthy Science Foundation of China, No. 2013KYA100 and No. 2009B043;the Public Welfare Technology Research Project of Zhejiang Province, No. 2010C34001
AIM: To investigate the potential roles of Delta-like ligand 4 (DLL4) on the biological behavior of gastric cancer cells and its molecular mechanisms. METHODS: A recombinant eukaryotic expression vector containing hum...
关键词：Gastric cancer Delta-like LIGAND 4/Notch Matrix METALLOPROTEINASE Migration INVASION 
Up-regulation of PIK3CA promotes metastasis in gastric carcinoma被引量：21
《World Journal of Gastroenterology》2010年第39期4986-4991,共6页Liu JF  Zhou XK  Chen JH  Yi G  Chen HG  Ba MC  Lin SQ  Qi YC. 
Supported by Medical Research Fund of Guangdong Province,No.A2007284;Health Bureau Fund of Guangzhou,No.2009-YB-169
AIM:To explore expressions of PIK3CA in the progression of gastric cancer from primary to metastasis and its effects on activation of phosphatidylinositol 3-kinase(PI3K)/Akt pathway.METHODS:mRNA and protein levels of ...
关键词：PIK3CA PHOSPHATIDYLINOSITOL 3-kinase/Akt pathway METASTASIS Gastric cancer AKT 
Up-regulation of hnRNP A1, Ezrin, tubulin β-2C and Annexin A1 in sentinel lymph nodes of colorectal cancer被引量：11
《World Journal of Gastroenterology》2010年第37期4670-4676,共7页Zhen-Yu He  Hao Wen Zhen-Yu He  Jie Wang  Chuan-Bing Shi  Jie Wang 
Supported by The Natural Science Basic Research Project,Education Department of Jiangsu Province, No. 08KJT310005;the 5th "Six Talent-Person-Peak Program", Jiangsu Province,China;Superior Item of Nanjing Medical University Science and Technology Progress Fund, No. 07NMUM047
AIM: To investigate the early metastasis-associated proteins in sentinel lymph node micrometastasis (SLNMM) of colorectal cancer (CRC) through comparative proteome. METHODS: Hydrophobic protein samples were extracted ...
关键词：Colorectal cancer MICROMETASTASIS PROTEOMICS Sentinel lymph node 
Up-regulation of α-catenin is associated with increased lymph node involvement in colorectal cancer被引量：1
《World Journal of Gastroenterology》2008年第31期4903-4908,共6页Adam Elzagheid Abdelbaset Buhmeida Eija Korkeila Yrj Collan Kari Syrjnen Seppo Pyrhnen 
Partly the Special Government Funding (EVO)allocated to Turku University Central Hospital and CancerSociety of South-West Finland (Turku), No. 13687
AIM: To investigate the changing pattern of α-catenin expression and its relationship to clinical and pathological features of colorectal cancer (CRC) patients. METHODS: Archival tumor samples were analyzed using imm...
关键词：Colorectal carcinoma ALPHA-CATENIN Membrane staining Cytoplasmic staining Prognosis 
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