HYPOXANTHINE

作品数：21被引量：17H指数：2
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相关领域：医药卫生更多>>
相关机构：西安交通大学更多>>
相关期刊：《Science China Chemistry》《Chinese Journal of Structural Chemistry》《Sports Medicine and Health Science》《Progress in Natural Science:Materials International》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Fatty acid oxidation-induced HIF-1α activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH被引量：2
《Life Metabolism》2024年第5期17-31,共15页Ningning Liang Xuan Yuan Lili Zhang Xia Shen Shanshan Zhong Luxiao Li Rui Li Xiaodong Xu Xin Chen Chunzhao Yin Shuyuan Guo Jing Ge Mingjiang Zhu Yongzhen Tao Shiting Chen Yongbing Qian Nicola Dalbeth Tony RMerriman Robert Terkeltaub Changgui Li Qiang Xia Huiyong Yin 
funded by grants from the National Key Research and Development Program of China(2022YFC2503300 and 2018YFA0800300);the National Natural Science Foundation of China(32030053 and 32241017);the startup fund from City University of Hong Kong(9380154);the RGC Theme-based Research Scheme(8770011);the TBSC Project fund,and Shenzhen Medical Research Fund(B2302042);R.T.was supported by the VA Research Service(I01 BX005927)and NIH(PAG007996).
Dyslipidemia affects approximately half of all people with gout,and prior Mendelian randomization analysis suggested a causal role for elevated triglycerides in hyperuricemia(HU),but the underlying mechanisms remain e...
关键词：DYSLIPIDEMIA HYPERURICEMIA PURINE HYPOXANTHINE metabolic flux 
A ratiometric fluorescent probe for hypoxanthine detection in aquatic products based on the enzyme mimics and fluorescence of cobalt-doped carbon nitride
《Food Science and Human Wellness》2024年第2期879-884,共6页Xin Wang Chengyi Hong Zhengzhong Lin Zhiyong Huang 
supported by the National Natural Science Foundation of China(21804050);the National Key R and D Program of China(2018YFD0901003);the Science and Technology Planning Project of Xiamen,China(3502Z20183031);the Fujian Provincial Fund Project(2018J01432);the Xiamen Science and Technology Planning Project,China(3502Z20183031)。
A ratiometric fluorescent probe for hypoxanthine(Hx)detection was established based on the mimic enzyme and fluorescence characteristics of cobalt-doped graphite-phase carbon nitride(Co doped g-C_(3)N_(4)).In addition...
关键词：Co doped g-C_(3)N_(4) Ratiometric fluorescent probe HYPOXANTHINE FRESHNESS Aquatic products 
Antihyperuricemic and Nephroprotective Effects of the Total Flavonoids from Carya cathayensis Leaves(CCTF)in Potassium Oxonate/hypoxanthine-induced Hyperuricemic Mice
《Clinical Complementary Medicine and Pharmacology》2023年第4期91-98,共8页Jiahui Hao Fangmei Zhou 
The Zhejiang Traditional Chinese Medicine Administration(CN)(Project No.2023ZF012).
Background:Abnormally high level of uric acid in the blood,defined as hyperuricemia(HUA),increases the chance of developing various disorders,such as gout,hypertension,and diabetes.There is a critical need to create s...
关键词：Leaves of Carya cathayensis HYPERURICEMIA Urate transporters Total flavonoids 
Whey protein peptide PEW attenuates hyperuricemia and associated renal inflammation in potassium oxonate and hypoxanthine-induced rat
《Food Bioscience》2023年第1期846-857,共12页Xiaofen Qi Yanfeng Ma Kaifang Guan Chunhong Liu Rongchun Wang Ying Ma Tianjiao Niu 
Pro-Glu-Trp(PEW),a whey protein-derived peptide,has been previously shown in vitro to have antihyperuricemic potential.The current study further evaluated the roles and the underlying mechanism of PEW in the managemen...
关键词：PEPTIDE HYPERURICEMIA Organic ion transporters Oxidative stress NLRP3 inflammasome TLR4/MyD88/NF-κB signaling pathway 
Fluorescent Copper Nanoclusters for Highly Sensitive Monitoring of Hypoxanthine in Fish被引量：1
《Journal of Analysis and Testing》2021年第1期76-83,共8页Zi-Xuan Zhao Ya-Ping Guo Jie Wei Quan-Sheng Chen Xiao-Mei Chen 
financially supported by the National Natural Science Foundation of China(32072299,21675062);the National Key R&D Program of China(2018YFD0901004);the Science and Technology Planning Project of Fujian Province,China(2020J01677)
Hypoxanthine(Hx)is an important freshness indicator reflecting the initial freshness of aquatic products.In this work,a novel fluorescence method was established based on cysteine functionalized copper nanoclusters(Cy...
关键词：Copper nanoclusters HYPOXANTHINE FRESHNESS Fluorescence FISH 
Utility of cardiac biomarkers in sports medicine:Focusing on troponin,natriuretic peptides,and hypoxanthine被引量：1
《Sports Medicine and Health Science》2020年第2期65-71,共7页Anirban Mahanty Lei Xi 
Evidence-based consensus suggests that physical activity and regular exercise training can reduce modifiable risk factors as well as rate of mortality and morbidity in patients with chronic diseases,such as cardiovasc...
关键词：BIOMARKER Cardiac troponin EXERCISE HYPOXANTHINE Natriuretic peptide Overtraining syndrome Tissue ischemia Risk factors 
Deposition Pattern of Inosine Monophosphate( IMP) in Pig Muscle during Cold Storage
《Animal Husbandry and Feed Science》2017年第4期197-199,218,共4页Zhu Rongsheng Wang Huaizhong Lin Song Wang Yanping Hu Hongmei 
Supported by National Natural Science Foundation of China(31501928);Youth Fund Project of Shandong Academy of Agricultural Sciences(2014QNM41);Science and Technology Development Program of Shandong Province(2015GNC111011);Natural Science Foundation of Shandong Province(ZR2015CM007)
[ Objective] The paper was to investigate the degradation and deposition changes of inosine monophosphate （IMP） and its metabolites in muscle of lean pigs and crossbreeding pigs under cold storage condition at 4℃. ...
关键词：Pig muscle IMP Inosine HYPOXANTHINE Deposition pattern 
Chemical Quality Indexes of Mullet (<i>Mugil platanus</i>) Stored on Ice
《Food and Nutrition Sciences》2014年第11期1030-1039,共10页Sabrina da Costa Silva Andrade Eliane Teixeira Mársico Ronoel Luiz de Oliveira Godoy Sidney Pacheco Robson Maia Franco Sérgio Borges Mano Carlos Adam Conte-Junior 
The present study was conducted aiming at establishing chemical quality parameters to assess ice stored mullet (0℃ ± 1℃) through the evaluation of nucleotide (adenosine monophosphate [AMP], inosine [HxR] and hypoxa...
关键词：Quality Parameters Biogenic Amines Nucleotides HYPOXANTHINE MUGILIDAE 
Determination of Hypoxanthine in the Presence of Copper by Adsorptive Stripping Voltammetry
《American Journal of Analytical Chemistry》2014年第5期291-300,共10页Percio Augusto Mardini Farias Arnaldo Aguiar Castro 
A stripping method for the determination of hypoxanthine in the presence of copper at the submicromolar concentration levels is described. The method is based on controlled adsorptive accumulation of hypoxanthine-copp...
关键词：HYPOXANTHINE DETERMINATION XANTHINE Uric Acid COPPER Ion ATP SSDNA Thin-Film Mercury Electrode Fast Linear Scan Stripping VOLTAMMETRY 
Determination of gouty arthritis' biomarkers in human urine using reversed-phase high-performance liquid chromatography被引量：4
《Journal of Pharmaceutical Analysis》2014年第2期153-158,共6页Lei-Wen Xiang Jing Li Jin-Ming Lin Hai-Fang Li 
supported by the National Natural Science Foundation of China(No.21275088)
Creatinine, uric acid, hypoxanthine and xanthine are important diagnostic biomarkers in human urine for gouty arthritis or renal disease diacrisis. A simple method for simultaneous determination of these biomarkers in...
关键词：Gouty arthritis CREATININE Uric acid HYPOXANTHINE XANTHINE High-performance liquid chromatography 
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