CHOLESTEROL-LOWERING

作品数:10被引量:55H指数:4
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相关领域:医药卫生更多>>
相关期刊:《Grain & Oil Science and Technology》《Science China(Life Sciences)》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金更多>>
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Hydrophilic phytosterol derivatives: A short review on structural modifications, cholesterol-lowering activity and safety被引量:2
《Grain & Oil Science and Technology》2022年第3期146-155,共10页Yuyuan Hu Chuanguo Ma Xiaowei Chen Ge Bai Shujing Guo 
supported by the National Natural Science Foundation of China(No.31972110)。
Phytosterols have received extensive attention owing to their excellent cholesterol-lowering activity and the role in cardiovascular diseases prevention. However, poor solubility in both oil and water limited the appl...
关键词:Hydrophilic modification Hydrophilic phytosterol derivatives Water solubility CHOLESTEROL-LOWERING Mechanism 
Key chemical composition of walnut(Juglans regia.L)Oils generated with different processing methods and their cholesterol-lowering effects in HepG2 cells被引量:3
《Food Bioscience》2022年第1期96-104,共9页Pan Gao Ruijie Liu Qingzhe Jin Xingguo Wang 
supported by the National Natural Science Foundation of China Youth Science Foundation Project(grant numbers 32001735).
We systematically evaluated fatty acids and triacylglycerol composition,as well as tocopherol,phytosterol,and phenolics,in walnut oil and compared the cholesterol-lowering effects of oil processed with different metho...
关键词:Walnut oil Processing method Cholesterol lowering PHENOLIC Phytosterols Juglans regia L 
Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats被引量:20
《Acta Pharmacologica Sinica》2020年第8期1085-1092,共8页Zhen-li Su Peng-zhou Hang Juan Hu Yu-yang Zheng Han-qi Sun Jing Guo Ke-yu Liu Zhi-min Du 
the Major Program of the National Natural Science Foundation of China(81230081);the Translational Fund of the Sino-Russian Medical Research Center,Heilongjiang Academy of Medical Sciences(CR201814).
Hyperlipidemia(HPL)characterized by metabolic disorder of lipids and cholesterol is one of the important risk factors for cardiovascular diseases.Proprotein convertase subtilsin/kexin type 9(PCSK9)is a potent circulat...
关键词:ALOE-EMODIN HYPERLIPIDEMIA CHOLESTEROL PCSK9 LDL receptor HepG2 cells ATORVASTATIN 
No Additional Cholesterol-Lowering Effect Observed in the Combined Treatment of Red Yeast Rice and Lactobacillus Casei in Hyperlipidemic Patients:A Double-Blind Randomized Controlled Clinical Trial被引量:1
《Chinese Journal of Integrative Medicine》2017年第8期581-588,共8页Chien-Ying Lee Min-Chien Yu Wu-Tsun Perng Chun-Che Lin Ming-Yung Lee Ya-Lan Chang Ya-Yun Lai Yi-Ching Lee Yu-Hsiang Kuan James Cheng-Chung Wei Hung-Che Shih 
Supported by the Committee on Chinese Medicine and Pharmacy,Department of Health,Taiwan,China(Protocol No.:CCMP97-RD-043);Chung Shan Medical University(Protocol No.:CSMU-INT-104-03)
Objective:To observe the effect of combining red yeast rice and Lactobacillus casei(L.casei)in lowering cholesterol in patients with primary hyperlipidemia,the later has also been shown to remove cholesterol in in ...
关键词:red yeast rice Lactobacillus casei low-density lipoprotein cholesterol randomizedcontrolled trial 
A novel class of apical sodium–dependent bile salt transporter inhibitors:1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides被引量:2
《Acta Pharmaceutica Sinica B》2017年第2期223-229,共7页Hongtao Liu Guoxun Pang Jinfeng Ren Yue Zhao Juxian Wang 
supported by the National Natural Science Foundation of China(Nos.81473098 and 81473099);Hebei Provincial Key Research Project of Medical Science(Nos.ZD20140027 and 20150588)
The apical sodium-dependent bile acid transporter(ASBT) is the main transporter to promote re-absorption of bile acids from the intestinal tract into the enterohepatic circulation.Inhibition of ASBT could increase the...
关键词:ASBT inhibitors Bile acids 1-(2 4-Bifluorophenyl)-7dialkylamino-1 8-naphthyridine-3-carboxa mides Cholesterol-lowering drug NC-1 
Use of Cholesterol-Lowering Medications of Patients with Myocardial Infarction from 2007-2015 in Cardiology Clinic to “Mother Teresa” University Hospital in Albania
《Pharmacology & Pharmacy》2016年第6期236-245,共10页Kleva Shpati Rudina Prifti Dritan Shpati Zana Bruci Erina Hilaj 
Background: Coronary Heart Disease (CHD) remains the leading cause of morbidity and mortality in Albania. According to Institute of Statistics of Albania (ISA), CHD remains in the 5 first places caused mortality and m...
关键词:STATINS FIBRATE Coronary Heart Disease Risk Factors Adverse Drug Events Etc. 
Isoflavones and phytosterols contained in Xuezhikang capsules modulate cholesterol homeostasis in high-fat diet mice被引量:11
《Acta Pharmacologica Sinica》2015年第12期1462-1472,共11页Dong FENG Jian-guo SUN Run-bin SUN Bing-chen OU-YANG Lan YAO Ji-ye AA Fang ZHOU Jing-wei ZHANG Jian ZHANG Guang-ji WANG 
The study was financially supported by the National Natural Science Foundation of China (81373481), Jiangsu Provincial Promotion Foundation for the Key Lab of Drug Metabolism and Pharmacokinetics (Grant No BM2012012) and the Key Technology Projects of China "Creation of New Drugs" (No 2015ZX09501001).
Aim: Xuezhikang (XZK), an extract of red yeast rice, has been widely used in traditional Chinese medicine to treat cardiovascular disease. Three fractions F1, F2 and F3 (primarily containing isoflavones, monacolin...
关键词:HYPERLIPIDEMIA cholesterol-lowering medication red yeast rice Xuezhikang Iovastatin ISOFLAVONES phytosterols CHOLESTEROL bile acids traditional Chinese medicine 
Effects of lactic acid bacteria isolated from fermented mustard on lowering cholesterol被引量:10
《Asian Pacific Journal of Tropical Biomedicine》2014年第7期523-528,共6页Shu Chen Wang Chen Kai Chang Shu Chang Chan Jiunn Shiuh Shieh Chih Kwang Chiu Pin-Der Duh 
Supported by research grants from the Ministry of Economic Affairs of Taiwan,the Republic of China with grant NO.98-EC-17-A-17-S1-132
Objective:To evaluate the ability of lactic acid bacteria(LAB)strains isolated from fermented mustard to lower the cholesterol in vitro.Methods:The ability of 50 LAB strains isolated from fermented mustard on lowering...
关键词:CHOLESTEROL-LOWERING activity Probiotic LACTIC ACID bacteria ACID BILE tolerance 
The Effect of a Dietary Supplement Spirulina and Bifidobacterium adolescentis on the Cholesterol-Lowering in Vitro and in Vivo被引量:1
《Journal of Life Sciences》2012年第7期740-746,共7页Amel Doumandji Dahmane Alili Abderrahmen Benzaiche 
The survey's results showed a significant percentage of women and especially men having an above normal cholesterol. In order to help reduce excessive rate of blood cholesterol, we used a local strain of Spirulina (...
关键词:SPIRULINA Bifidobacterium adolescentis hypocholesterolemic activity in vitro in vivo. 
Purification and characterization of a novel cholesterol-lowering protein from the seeds of Senna obtusifolia被引量:5
《Science China(Life Sciences)》2008年第11期1020-1024,共5页LI ChuHua1, LI Mei2, CHANG WenRui2 & GUO BaoJiang1 1 College of Life Sciences, South China Normal University, Guangdong Provincial Key Lab of Biotechnology of Plant Development, Guang-zhou 510631, China 2 Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China 
Guangdong Provincial Department of Science and Technology (Grant No. 2003C34409);Guangzhou Civil Department of Science and Technology (Grant No. 2002Z3-85041)
"Juemingzi", a source of traditional Chinese herbal medicine, has been demonstrated to play a role in decreasing serum cholesterol concentration. In this study, a novel protein, which has shown an in-hibitory effect o...
关键词:SENNA obtusifolia L. seed NOVEL PROTEIN purification biochemical properties CHOLESTEROL BIOSYNTHESIS 
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