GLYCOME

作品数:7被引量:2H指数:1
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Small but big leaps towards neuroglycomics:exploring N-glycome in the brain to advance the understanding of brain development and function
《Neural Regeneration Research》2024年第3期489-490,共2页Boyoung Lee Hyun Joo An 
supported by the Institute for Basic Science(IBS-R001-D2-2022-A03).
Glycosylation is a process that involves the addition of sugar moieties or glycans to different types of molecules,including proteins,lipids,and nucleic acids.Among these,protein glycosylation is one of the most preva...
关键词:functions FUNCTION apparatus 
人类蛋白质N-糖基化的十二年全基因组关联研究
《Engineering》2023年第7期17-31,I0001,I0002,共17页Anna Timoshchuk Sodbo Sharapov Yurii S.Aulchenko 
an output of a research project implemented as part of the Research Program at the Moscow State University (MSU) Institute for Artificial Intelligence.
Most human-secreted and membrane-bound proteins have covalently attached oligosaccharide chains or glycans.Glycosylation influences the physical and chemical properties of proteins,as well as their biological function...
关键词:GLYCOME GLYCANS N-GLYCOSYLATION Genomics Genetics GWAS 
Control of lupus activity during pregnancy via the engagement of IgG sialylation:novel crosstalk between IgG sialylation and pDC functions
《Frontiers of Medicine》2023年第3期549-561,共13页You Wang Sihan Lin Jiayue Wu Meng Jiang Jianhua Lin Yu Zhang Huihua Ding Haibo Zhou Nan Shen Wen Di 
supported by grants from the National Natural Science Foundation of China(Nos.82172918,81901494,82101768,82171767,and 81974252);the Science and Technology Commission of Shanghai Municipality(No.18441904800);the Medical-Engineering Joint Funds of Shanghai Jiao Tong University(No.YG2021GD01);the Shanghai Key Laboratory of Gynecologic Oncology(No.FKZL-2021-02);Shanghai Health Commission(No.201940284);the Clinical Scientific Research Innovation Cultivation Fund of Renji Hospital(No.PYI20-03).
Immunoglobulin(IgG)glycosylation affects the effector functions of IgG in a myriad of biological processes and has been closely associated with numerous autoimmune diseases,including systemic lupus erythematosus(SLE),...
关键词:PREGNANCY IgG glycome typeⅠinterferon systemic lupus erythematosus 
Possible role of sialylation of retinal protein glycans in the regulation of electroretinogram response in mice
《International Journal of Ophthalmology(English edition)》2017年第8期1217-1222,共6页Satpal Ahuja 
Supportted by Ogonfonden Synframjande Forskning,Stod Ogonforskningen,Umea(Sweden);Stiftelsen Kronprinsessan Margaretas Arbetsnamnd for synskadade(KMA,Sweden);Stiftelsen for synskadade i.f.d Malmohus Lan,Malmo(Sweden)
AIM: To evaluate if the nature, degree and extent of Siaa2-3-/Siaa2-6-sialylation of retinal protein glycans plays a possible role in the development and regulation of electroretinogram response (ERG) in mice. MET...
关键词:electroretinogram response GLYCOME lectin microarray mice retinae retinal development and degeneration 
Global Insight into N-Glycome and N-Glycoproteome of Three Most Abundant Snake Venoms in Asia
《Chemical Research in Chinese Universities》2014年第5期726-730,共5页CAO Weiqian HUANG Jiangming CAO Jing YANG Pengyuan 
Supported by the National Basic Research Program of China(No.2013CB911201), the National High Technology Research and Development Program of China(No.2012AA020200), the National Natural Science Foundation of China(No.31100590) and the Shanghai Municipal Natural Science Foundation, China(No. 11ZR1403000).
Snake venom is a complex cocktail including a variety of biological active proteins and proteinaceous components, which have considerable medical and pharmacological importance. N-Glycosylation is widely impli- cated ...
关键词:GLYCOSYLATION N-Glycomics N-Glycoproteomics Snake venom 
Alteration of liver N-glycome in patients with hepatocellular carcinoma被引量:2
《Open Journal of Gastroenterology》2012年第1期1-8,共8页Ling Wang Valerie Vanhooren Sylviane Dewaele Xue-En Liu Claude Libert Feng-Min Lu Hui Zhuang Cuiying Chitty Chen 
Purpose: Alteration of liver function during pro- gression of hepatocellular carcinoma (HCC) and cirrhosis affects the serum glycoprotein pattern. In this study, the changes in the N-glycome in liver tis- sue from pat...
关键词:N-Glycome DSA-FACE FUCOSYLATION HCC CIRRHOSIS 
Detecting cancer cell-surface glycome profilings by lectin microarray
《生物物理学报》2009年第S1期203-204,共2页Chun-Hui Li 1, Qun He 1, Yu-Jie Zhao1 1 Biochip Center, Key Laboratory of Cell Biology, Ministry of Public Health of China, China Medical University, Shenyang 110001, China 2 Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China 
supported by a grant from the National Natural Science Foundation of China (20672144)
Objective: Glycomics is an emerging field in the postgenome and postproteome era. Glycosylation changes of cell-surface have been observed in tumour cell progression
关键词:LECTIN MICROARRAY GLYCOME profilings BIOMARKER 
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