The incidence of chronic immune-mediated diseases is increasing worldwide across all age groups,affecting more than 10%of the general population[1,2].Immune-mediated diseases are also more likely to be associated with...
BACKGROUND Hepatic eosinophilic pseudotumor(HEPT)is a rare condition that mimics ma-lignant hepatic tumors,posing significant diagnostic challenges.This case report highlights the importance of considering parasitic i...
BACKGROUND Eosinophilic solid and cystic(ESC)renal cell carcinoma(RCC),a unique and emerging subtype of RCC,has an indolent nature;in some rare instances,it may exhibit metastatic potential.Current cases are inadequat...
Daptomycin induced acute eosinophilic pneumonia is a rare and potentially life threatening condition characterized by rapid respiratory failure, pulmonary infiltrates and eosinophilia. Risk factors for acute eosinophi...
BACKGROUND Toxic epidermal necrolysis(TEN)is a life-threatening dermatological emergency mainly induced by drug hypersensitivity reactions.Standard management includes discontinuation of culprit drug and application o...
Supported by the 2020 National Natural Science Foundation Cultivation Project of Guizhou Medical University Affiliated Hospital,No.gyfynsfc[2020]-14.
BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,an...
Supported by a Japan Society for the Promotion of Science KAKENHI Grant-in-Aid for Young Scientists,No.20K16905.
BACKGROUND Eosinophilic gastrointestinal disease(EGID)is a disorder characterized by infiltration of eosinophils causing mucosal damage and dysfunction of the gastrointestinal tract.The endoscopic findings of eosinoph...
The small and medium sized vessels vasculitis included in the group of vasculitis associated with anti-neutrophil cytoplasmic antibodies,is a rare disease characterized by the presence of vasculitis in association wit...
National Natural Science Foundation of China(No. 31972189)
Hypereosinophilic syndrome(HES),a rare systemic disease,was first described in 1968.As a subtype of HES,idiopathic hypereosinophilic syndrome(IHES)is defined as hypereosinophilia of unknown cause,excluding tumor,infec...
This work was supported by grants from the National Natural Science Foundation of China(32188101,31830024 and 32070775);the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-071);the Fundamental Research Funds for the Central Universities.
Interleukin 5(IL-5)plays crucial roles in type 2-high asthma by mediating eosinophil maturation,activation,chemotaxis and survival.Inhibition of IL-5 signaling is considered a strategy for asthma treatment.Here,we ide...