CHOLANGIOCYTES

作品数：30被引量：138H指数：8
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相关领域：医药卫生更多>>
相关作者：季维智金立方纪少珲杨纪峰更多>>
相关机构：绍兴文理学院中国科学院温州医学院上海中医药大学附属曙光医院更多>>
相关期刊：《Chinese Herbal Medicines》《Chinese Journal of Natural Medicines》《Virologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划上海市浦江人才计划项目更多>>
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A G3P[3]bat rotavirus can infect cultured human cholangiocytes and cause biliary atresia symptom in suckling mice
《Virologica Sinica》2024年第6期974-976,共3页Pengfei Hao Zhaoxia Pang Qiaoqiao Qu Chunmei Cui Yuhang Jiang Jing Chen Zihan Gao Zhiqiang Xu Letian Li Ningyi Jin Chang Li 
Dear Editor,Rotavirus(RV),a member of the Reoviridae family,is non-enveloped virus with a genome consisting of 11 segments of double-stranded RNA.It possesses a three-layered shell structure,and can be classified into...
关键词：BALB/C envelope 
Danhongqing formula alleviates cholestatic liver fibrosis by downregulating long non-coding RNA H19 derived from cholangiocytes and inhibiting hepatic stellate cell activation
《Journal of Integrative Medicine》2024年第2期188-198,共11页Meng Li Yang Zhou Hui Zhu Lie-ming Xu Jian Ping 
supported by grants from the National Natural Science Foundation of China(No.81773980);Project of Science and Technology Commission of Shanghai Municipality(No.15401902600)。
Objective:This study explores the mechanism of action of Danhongqing formula(DHQ),a compoundbased Chinese medicine formula,in the treatment of cholestatic liver fibrosis.Methods:In vivo experiments were conducted usin...
关键词：Liver cirrhosis BILIARY Long non-coding RNA H19 Danhongqing formula CHOLANGIOCYTE Hepatic stellate cells STAT3 transcription factor 
Chuanxiong Rhizoma extracts prevent liver fibrosis via targeting CTCF-c-MYC-H19 pathway被引量：4
《Chinese Herbal Medicines》2024年第1期82-93,共12页Yajing Li Fanghong Li Mingning Ding Zhi Ma Shuo Li Jiaorong Qu Xiaojiaoyang Li 
supported by the Beijing Municipal Science&Technology Commission(No.7212174);the National High-Level Talents Special Support Program to XL;National Key Research and Development Program on Modernization of Traditional Chinese Medicine(No.2022YFC3502100);National Natural Science Foundation of China(No.82004045 and No.82274186).
Objective:Hepatic fibrosis has been widely considered as a conjoint consequence of almost all chronic liver diseases.Chuanxiong Rhizoma(Chuanxiong in Chinese,CX)is a traditional Chinese herbal product to prevent cereb...
关键词：Chuanxiong Rhizoma CHOLANGIOCYTES ductular reaction Ligusticum chuanxiong Hort. liver fibrosis lncRNA H19 
Chuanxiong Rhizoma extracts prevent cholestatic liver injury by targeting H3K9ac-mediated and cholangiocyte-derived secretory protein PAI-1 and FN
《Chinese Journal of Natural Medicines》2023年第9期694-709,共16页LI Yajing MA Zhi DING Mingning JIA Kexin XU Bing ZHOU Fei LUO Ranyi XUE Xiaoyong WU Ruiyu GAO Feng LI Xiaojiaoyang 
the Beijing Municipal Science&Technology Commission(No.7212174);the National High-Level Talents Special Support Program to XL,the National Natural Science Foundation of China(Nos.82274186 and 82004045);National Key Research and Development Program on Modernization of Traditional Chinese Medicine(No.2022YFC-3502100);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202006).
Chuanxiong Rhizoma(CX,the dried rhizome of Ligusticum wallichii Franch.),a well-known traditional Chinese medicine,is clinically used for treating cardiovascular,cerebrovascular and hepatobiliary diseases.Cholestatic ...
关键词：Chuanxiong Rhizoma Cholestatic liver injury Ductular reaction CHOLANGIOCYTES Hepatic stellate cell 
Liver cell therapies:cellular sources and grafting strategies被引量：1
《Frontiers of Medicine》2023年第3期432-457,共26页Wencheng Zhang Yangyang Cui Yuan Du Yong Yang Ting Fang Fengfeng Lu Weixia Kong Canjun Xiao Jun Shi Lola M.Reid Zhiying He 
funded by Major Program of National Key Research and Development Project(Nos.2020YFA0112600 and 2019YFA0801502);National Natural Science Foundation of China(Nos.82173019,82270638,and 82203741);Shanghai Pujiang Program(No.21PJD059);the Project of Shanghai Science and Technology Commission(Nos.22ZR1451100,19140902900,and 22Y11908500),Program of Shanghai Academic/Technology Research Leader(No.20XD1434000);Peak Disciplines(Type Ⅳ)of Institutions of Higher Learning in Shanghai,Jiangxi Provincial Natural Science Foundation(No.20212ACB206033);Shanghai Engineering Research Center of Stem Cells Translational Medicine(No.20DZ2255100);funded by Vesta Therapeutics(Bethesda,MD),an NIH grant(HL051587)awarded to J.Piedrahita(NCSU,Raleigh,NC);funding from the UNC School of Medicine,the Fibrolamellar Carcinoma Foundation(Greenwich,CT);by multiple NIH Core and Center grants(5P41EB002025);Center for Gastrointestinal and Biliary Disease Biology(NIDDK Grant:P30 DK034987);the Lineberger Cancer Center grant(NCI grant#CA016086).
The liver has a complex cellular composition and a remarkable regenerative capacity.The primary cell types in the liver are two parenchymal cell populations,hepatocytes and cholangiocytes,that perform most of the func...
关键词：liver regeneration HEPATOCYTES CHOLANGIOCYTES stem cells ORGANOIDS regulatory mechanisms transplantation/grafting strategies 
Morphological aspects of small-duct cholangiopathies:A minireview
《World Journal of Hepatology》2023年第4期538-553,共16页Eva Sticova Ondrej Fabian 
The biliary system consists of intrahepatic and extrahepatic bile ducts lined by biliary epithelial cells(cholangiocytes).Bile ducts and cholangiocytes are affected by a variety of disorders called cholangiopathies,wh...
关键词：Bile duct CHOLANGIOCYTES CHOLANGIOPATHY CHOLANGITIS Liver biopsy HISTOPATHOLOGY 
Secondary bile acids and the biliary epithelia: The good and the bad被引量：1
《World Journal of Gastroenterology》2023年第2期357-366,共10页Ilaria Lenci Martina Milana Alessandro Signorello Giuseppe Grassi Leonardo Baiocchi 
The biliary tract has been considered for several decades a passive system just leading the hepatic bile to the intestine.Nowadays several researches demonstrated an important role of biliary epithelia(i.e.cholangiocy...
关键词：CHOLANGIOCYTES Biliary secretion CHOLESTASIS Bile acids Secondary bile acids Ursodeoxycholic acid Lithocholic acid 
Mitochondrial calcium signaling in cholangiocarcinoma
《Hepatoma Research》2023年第1期326-336,共11页Ana Carolina Loyola-Machado Mateus T.Guerra Michael H.Nathanson 
supported by the Gladys Phillips Crofoot Professorship and grants from the National Institutes of Health(P30-DK34989,R01-AA028765,R01-DK114041,R01-DK112797).
Cholangiocarcinoma(CCA)is a primary liver cancer whose diagnosis and treatment remain challenging.Although recent developments derived from molecular characterization of CCAs have led to the availability of new pharma...
关键词：CHOLANGIOCARCINOMA CHOLANGIOCYTES MITOCHONDRIA inositol 1 4 5-trisphosphate-receptors calcium signaling membrane contact sites mitochondria-associated endoplasmic reticulum membranes apoptosis cell proliferation energy metabolism 
COVID-19 and liver disease: Are we missing something?被引量：2
《World Journal of Hepatology》2022年第2期479-481,共3页Tarana Gupta 
Since the coronavirus disease 2019(COVID-19)has hit the world as a pandemic,researchers all over the world have worked on its diagnostics,prognosticating factors,etc.The present study showed liver enzymes,especially a...
关键词：COVID-19 Liver disease TRANSAMINASES Non-alcoholic fatty liver disease HEPATOCYTES CHOLANGIOCYTES 
Fibroblast Growth Factor 19 Induced Changes in Non-malignant Cholangiocytes被引量：1
《Journal of Clinical and Translational Hepatology》2021年第6期909-916,共8页Jiaqi Yang David Sontag Sam Kung Gerald Y.Minuk 
Background and Aims:Fibroblast growth factor(FGF)19 has been implicated in the pathogenesis of murine hepatocellular carcinoma.Whether it plays a role in the development or course of human cholangiocarcinoma remains t...
关键词：Fibroblast growth factor 19 CHOLANGIOCYTES CHOLANGIOCARCINOMA Farnisoid x receptor Obetcholic acid 
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