AURANOFIN

作品数：4被引量：25H指数：2
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相关领域：医药卫生更多>>
相关作者：李振宇丁小军更多>>
相关机构：华中科技大学武汉大学更多>>
相关期刊：《Signal Transduction and Targeted Therapy》《Neural Regeneration Research》《World Journal of Clinical Infectious Diseases》《Cancer Drug Resistance》更多>>
相关基金：国家自然科学基金更多>>
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Auranofin and its analogs as prospective agents for the treatment of colorectal cancer被引量：1
《Cancer Drug Resistance》2022年第1期1-14,共14页Lara Massai Damiano Cirri Tiziano Marzo Luigi Messori 
funding the project“Advanced mass spectrometry tools for cancer research:novel applications in proteomics,metabolomics and nanomedicine”(Multi-user Equipment Program 2016,Ref.code 19650);the Beneficentia Stiftung,Vaduz(BEN2019/48 and University of Pisa(Rating Ateneo 2019-2020)for the financial support;supported by the University of Pisa under the“PRA-Progetti di Ricerca di Ateneo”Institutional Research Grants-Project no.PRA_2020_58“Agenti innovativi e nanosistemi per target molecolari nell’ambito dell’oncologia di precisione”to Marzo T;the financial support(two-year fellowship for Italy“Marcello e Rosina Soru”-Project Code:23852).
Today colorectal cancer(CRC)is one of the leading causes of cancer death worldwide.This disease is poorly chemo-sensitive toward the existing medical treatments so that new and more effective therapeutic agents are ur...
关键词：AURANOFIN CRC colorectal cancer METALLODRUGS anticancer agents GOLD gold-based drugs 
Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms被引量：20
《Signal Transduction and Targeted Therapy》2020年第1期1239-1247,共9页Lei Yang Hao Wang Xiang Yang Qian Wu Peng An Xi Jin Weiwei Liu Xin Huang Yuzhu Li Shiyu Yan Shuying Shen Tingbo Liang Junxia Min Fudi Wang 
supported by research grants from the National Natural Science Foundation of China(31530034 and 31930057 to F.W.,31570791 to J.M.,31701035 to H.W.,31701034 to Q.W.,and 81500984 to L.Y.);the National Key Research and Development Program of China(2018YFA0507802 to F.W.,2018YFA0507801 to J.M.).
Iron homeostasis is essential for health;moreover,hepcidin-deficiency results in iron overload in both hereditary hemochromatosis and iron-loading anemia.Here,we identified iron modulators by functionally screening he...
关键词：PEROXIDATION OVERLOAD MECHANISMS 
Antioxidant enzyme profile of two clinical isolates of Entamoeba histolytica varying in sensitivity to antiamoebic drugs
《World Journal of Clinical Infectious Diseases》2017年第2期21-31,共11页Lakshmi Rani Iyer Neha Banyal Shailendra Naik Jaishree Paul 
Supported by WOS-A grant from Department of Science and Technology,New Delhi,Government of India to Iyer LR,No.SR/WOS-A/LS-98/2007;"Programme support on molecular parasitology",Department of Biotechnology,New Delhi,India to Paul J,No.BT/01/CEIB/11/v/08
AIM To study the sensitivity and antioxidant enzyme response in two clinical isolates of Entamoeba histolytica(E. histolytica) during treatment with antiamoebic drugs,auranofin and metronidazole. METHODS E. histolytic...
关键词：METRONIDAZOLE ENTAMOEBA HISTOLYTICA AMOEBIASIS THIOREDOXIN reductase Minimum inhibitory concentrations AURANOFIN 
A new look at auranofin,dextromethorphan and rosiglitazone for reduction of glia-mediated inflammation in neurodegenerative diseases被引量：4
《Neural Regeneration Research》2015年第3期391-393,共3页Jocelyn M.Madeira Stephanie M.Schindler Andis Klegeris 
supported by a grant from the Jack Brown;Family Alzheimer’s Disease Research Foundation
Neurodegenerative disorders including Alzheimer＇s disease are characterized by chronic in- flammation in the central nervous system. The two main glial types involved in inflammatory reactions are microglia and astro...
关键词：AURANOFIN DEXTROMETHORPHAN ROSIGLITAZONE Alzheimer＇s disease neuroinflammation NEURODEGENERATION rnicroglia ASTROCYTES 
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