云南高校图书馆联盟文献共享服务平台- Α1-ADRENOCEPTOR

Α1-ADRENOCEPTOR: 作品数：14被引量：10H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关机构：延边大学更多>>; 相关期刊：《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》《World Journal of Cardiology》更多>>; 相关基金：国家重点基础研究发展计划国家自然科学基金广东省自然科学基金更多>>

Onset Time Profiles for Syncope Associated with α1-Adrenoceptor Blockers in Males: Analysis of a Spontaneous Adverse Drug Event Database: 《Pharmacology & Pharmacy》2018年第12期515-526,共12页Katsuhiro Ohyama Masaya Furumoto Munetoshi Sugiura; Background: α1-Adrenoceptor blockers (α1Bs) are used for the treatment of benign prostatic hyperplasia and hypertension, but they are known to cause hypotension-related adverse events. The objective of the present s...; 关键词：Reporting Odds Ratio Adverse Drug Event Report DATABASE SYNCOPE Α1-ADRENOCEPTOR Blocker

Clonidine Inhibits Phenylephrine-Induced Contraction of Rat Thoracic Aortae by Competitive Antagonism of α1-Adrenoceptors Independent of α2-Adrenoceptor Stimulation: 《Pharmacology & Pharmacy》2017年第5期172-188,共17页Daisuke Chino Mai Naramatsu Keisuke Obara Yoshio Tanaka; Clonidine is a classically categorized α2-adrenoceptor (α2-AR) agonist that produces vascular contractions by stimulating arterial smooth muscle α2-ARs. However, clonidine inhibits α1-AR-mediated arterial contract...; 关键词：CLONIDINE α2-Adrenoceptor (α2-AR) Α1-ADRENOCEPTOR (α1-AR) RAT Aorta Relaxation

Differential effects of short- and long-term bupivacaine treatment on α1-adrenoceptor-mediated contraction of isolated rat aorta rings and the reversal effect of lipid emulsion被引量：1: 《Acta Pharmacologica Sinica》2015年第8期976-986,共11页Hao GUO He-feiZHANG Wen-qi XU Qian DU Jing ZHAO Lei-ming REN; Aim： Arterial function is significantly influenced by bupivacaine at both clinically relevant concentrations and toxic concentrations, but the underlying mechanisms are not fully understood. In the present study we i...; 关键词：BUPIVACAINE aortic rings α1-adrenoceptors PHENYLEPHRINE VASOCONSTRICTION ACETYLCHOLINE VASODILATION lipids emulsions local anesthetics

Insights into cardio-oncology:Polypharmacology of quinazoline-based α1-adrenoceptor antagonists: 《World Journal of Cardiology》2015年第5期238-242,共5页Salvatore Patanè; New uses of cardiovascular drugs with proven experience are emerging,including for treating cancer.Quinazoline is a compound made up of two fused six member simple aromatic rings,benzene and pyrimidine rings,with seve...; 关键词：Cardio-oncology Multidrug resistance PRAZOSIN TERAZOSIN Doxazosin

Co-Localization of Alpha1-Adrenoceptors and GPR55: A Novel Prostate Cancer Paradigm?: 《Pharmacology & Pharmacy》2015年第4期212-220,共9页Kalyani Chimajirao Patil Laura McPherson Craig James Daly; α1-adrenoceptors (α1-ARs) and “cannabinoid-like” G Protein Coupled Receptor 55 (GPR55) belong to the G-protein coupled receptor (GPCR) family and play a crucial role in regulating prostate function. Although physi...; 关键词：PROSTATE Α1-ADRENOCEPTOR GPR55 DOXAZOSIN

Synthesis, Crystal Structure and Biological Activity of N-(2-hydroxy-3-(4-(2-methoxyphenyl)-piperazin-1-yl)propyl)quinoxaline-2-methanamide: 《Chinese Journal of Structural Chemistry》2015年第4期497-502,共6页黄敏怡徐未黄珺珺黄亚建袁牧; supported by the Technological Innovation Project of Colleges and Universities in Guangdong Province(No.cx2d1127);the Natural Science Foundation of Guangdong Province(No.S2013040014088); The title compound N-（2-hydroxy-3-（4-（2-methoxyphenyl）piperazin-l-yl）propyl）- quinoxaline-2-methanamide （4, C23H27N5O3, Mr = 421.50） was synthesized via a four-step reaction and characterized by ^1H NMR, ^13C ...; 关键词：benign prostatic hyperplasia SYNTHESIS crystal structure α1-adrenoceptors

Selective α1B- and α1D-adrenoceptor antagonists suppress noradrenaline-induced activation, proliferation and ECM secretion of rat hepatic stellate cells in vitro被引量：1: 《Acta Pharmacologica Sinica》2014年第11期1385-1392,共8页Ting-ting LIU Ti-long DING Yong MA Wei WEI; Acknowledgements This study was supported by the National Natural Science Foundation of China （No 81173075） and the Nanjing Military Medical Science and Technology Innovation Foundation of China （No 10MA037）.; Aim： To explore the effects of noradrenaline （NA） on hepatic stellate cells （HSCs） in vitro and to determine the adrenoceptor （AR） subtypes and underlying mechanisms. Methods： The distribution and expressions ...; 关键词：NORADRENALINE hepatic fibrosis hepatic stellate cell Α1-ADRENOCEPTOR G. PKC PI3K AKT

（-）Doxazosin is a necessary component for the hypotensive effect of （±）doxazosin during long-term administration in conscious rats被引量：4: 《Acta Pharmacologica Sinica》2014年第1期48-57,共10页Jing ZHAO De-zhi KONG Qing LI Ya-qin ZHEN Miao WANG Yan ZHAO Dong-kai WANG Lei-ming REN; Aim： Doxazosin is a racemic mixture of （–）doxazosin and （＋）doxazosin that is currently used as an add-on therapy for hypertension. In this study we investigated the contribution of each enantiomer to the hypot...; 关键词：DOXAZOSIN ENANTIOMER blood pressure HYPOTENSION plasma drug concentration Α1-ADRENOCEPTOR NORADRENALINE tail artery conscious rat

Vascular Damages in Rats Immunized by α_1-Adrenoceptor Peptides被引量：1: 《Cellular & Molecular Immunology》2008年第5期349-356,共8页Zihua Zhou Yuhua Liao Liudong Li Fen Wei Bin Wang Yumiao Wei Min Wang Xiang Cheng; a grant from the State Key Basic Research Program of China (No. G2000056900).; Autoantibodies against the α1-adrenoceptor which had agonist activity as norepinephrine might play roles in the progression of hypertension, but whether the autoantibodies could induce vascular remodeling as norepine...; 关键词：Α1-ADRENOCEPTOR AUTOANTIBODY vascular remodeling

Functional subtypes of renal α1-adrenoceptor in diabetic and non-diabetic 2KIC Goldblatt renovascular hypertension: 《Acta Pharmacologica Sinica》2008年第5期564-572,共9页A ARMENIA Munavvar Abdul SATTAR Nor Azizan ABDULLAH Md Abdul Hye KHAN Edward James JOHNS; Aim： This study investigates the subtypes of the α1-adrenoceptor mediating the adrenergically-induced renal vasoconstrictor responses in streptozotocin-induced diabetic and non-diabetic 2-kidney one clip （2K1C） Go...; 关键词：renovascular hypertension 2-kidney one clip Goldblatt hypertensive rats hypertension diabetes KIDNEY

Α1-ADRENOCEPTOR