CLONIDINE

作品数：31被引量：55H指数：4
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相关领域：医药卫生更多>>
相关作者：徐永明杜冬萍江伟余东游冯杰更多>>
相关机构：上海交通大学附属第六人民医院浙江大学复旦大学华中科技大学更多>>
相关期刊：《国际眼科杂志》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Treatment of prolonged clonidine-induced autonomic instability with midodrine:a case report about a new approach or a cautionary tale?
《Emergency and Critical Care Medicine》2023年第4期194-197,共4页Saada Malouf Catherine Henry Lara Pemberton Joe-Anthony Rotella 
Background:Clonidine is a centrally acting a2 adrenergic and imidazoline-1 receptor agonist that can cause somnolence,bradycardia,and hypotension within several hours of ingestion.Less well-described but observed by u...
关键词：AUTONOMIC Case report CLONIDINE INSTABILITY Midodrine OVERDOSE 
Alpha2-adrenergic receptor activation reinstates motor deficits in rats recovering from cortical injury被引量：1
《Neural Regeneration Research》2023年第4期875-880,共6页Gabriela García-Díaz Laura ERamos-Languren Carmen Parra-Cid Joel Lomelí Sergio Montes Camilo Ríos Antonio Bueno-Nava Ignacio Valencia-Hernández Rigoberto González-Piña 
supported by Consejo Nacional de Ciencia y Tecnología(CONACy T)project CB 2016-287614(to RGP and ABN);by Scholarship Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica de la Universidad Nacional Autónoma de México(PAPIIT-UNAM)IA203319 and PAPIIT-UNAM IN216221 to(LERL)。
Norepinephrine plays an important role in motor functional recovery after a brain injury caused by ferrous chloride.Inhibition of norepinephrine release by clonidine is correlated with motor deficits after motor corte...
关键词：alpha2-adrenoceptors ambulatory behavior CLONIDINE cortical injury EFAROXAN functional recovery immunohistochemistry motor deficit norepinephrine sensorimotor score 
Clonidine use during dexmedetomidine weaning:A systematic review
《World Journal of Critical Care Medicine》2023年第1期18-28,共11页Sanu Rajendraprasad Molly Wheeler Erin Wieruszewski Joseph Gottwald Lindsey A.Wallace Danielle Gerberi Patrick M Wieruszewski Nathan J Smischney 
BACKGROUND Dexmedetomidine is a centrally acting alpha-2A adrenergic agonist that is commonly used as a sedative and anxiolytic in the intensive care unit(ICU),with prolonged use increasing risk of withdrawal symptoms...
关键词：CLONIDINE DEXMEDETOMIDINE Intensive care unit WITHDRAWAL WEANING 
Effects of Dexamethasone, Clonidine, Tramadol and Nalbuphine on Fentanyl-Induced Hyperalgesia in Rats被引量：1
《Journal of Biosciences and Medicines》2021年第12期87-97,共11页Camila dos Santos Leite Naira Correia Cusma Pelógia Eliane Stevanato Marília Hidalgo Uchôas Marta Helena Rovani Pires Oscar César Pires 
Opioids are drugs used to alleviate pain. However, studies have demonstrated that these drugs can cause an increase in pain sensitivity, which is called opioid-induced hyperalgesia. The objective of this study was to ...
关键词：HYPERALGESIA FENTANYL DEXAMETHASONE CLONIDINE TRAMADOL NALBUPHINE Rats 
Comparison of Clonidine and Metoprolol Effectiveness on the Control of Post-Operative Blood Pressure in Otorhinolaryngology-Head and Neck Surgeries: A Clinical Trial
《Open Journal of Anesthesiology》2021年第2期49-58,共10页Sérgio Menezes Silvio Caldas Neto Ruy Lins Filho Jayme Santos Neto Rossana Lins 
Objectives: Adequate control of hemodynamic parameters in patients undergoing otolaryngology-head and neck (OLHN) surgeries is one of the objectives of peri-operative anesthesia management. In this context, we seek to...
关键词：CLONIDINE METOPROLOL Hypertension POST-OPERATIVE 
A Comparative Study of Intrathecal Injection of Bupivacaine Alone or with Fentanyl, Clonidine, and Neostigmine in Lower Abdominal Surgeries
《Open Journal of Anesthesiology》2019年第4期83-98,共16页Elsayed Mohamed Abdelzaam Ahmed Hamdy Abd Elrahman 
Background: Anesthesiologists are responsible for the development of pain services in the current era. Hence ideal adjuvants that can be used with bupivacaine for stable intraoperative conditions and prolonging the po...
关键词：INTRATHECAL BUPIVACAINE FENTANYL NEOSTIGMINE CLONIDINE 
Differences in the Receptor Binding Profile of Lofexidine Compared to Clonidine
《Pharmacology & Pharmacy》2019年第1期1-10,共10页Robert B. Raffa Joseph V. Pergolizzi Robert Taylor Robert P. James Mark Pirner 
Lucemyra? (lofexidine hydrochloride) has recently been approved by the US FDA for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults. Lofexidine is an alpha-2 adrenoceptor ...
关键词：Lofexidine CLONIDINE OPIOID WITHDRAWAL Receptor AFFINITY Alpha-2 AGONIST 
Effect of clonidine on the cutaneous silent period during spinal anesthesia被引量：1
《World Journal of Clinical Cases》2018年第16期1136-1145,共10页Sandra Graf Zupcic Miroslav Zupcic Viktor Duzel Tatjana imurina Milan Miloevi Silvio Basic Vladimira Vuletic Leonardo Kapural 
AIM To investigate the effect of clonidine on the cutaneous silent period(CSP) during spinal anesthesia. METHODS A total of 67 adult patients were included in this randomized, prospective, single-center, double-blind ...
关键词：CLONIDINE Local ANESTHETICS NERVE fibers SPINAL ANESTHESIA REFLEX 
Safety threshold of intravitreal clonidine in rabbit's eyes被引量：1
《International Journal of Ophthalmology(English edition)》2018年第1期25-30,共6页Homayoun Nikkhah Kiumars Heidari Garfami Mozhgan Rezaei Kanavi Ebrahim Mohammad Nashtaei Saeed Karimi Masoud Soheilian 
AIM： To determine the safe dose of intravitreal clonidine（IVC）, a potential drug for neuroprotection and angiogenesis inhibition in rabbits. METHODS： A total of 28 rabbits were divided into four groups. Three grou...
关键词：clonidine intravitreal injection electroretinography glial fibrillary acidic protein TUNEL assay 
Clonidine Inhibits Phenylephrine-Induced Contraction of Rat Thoracic Aortae by Competitive Antagonism of α<sub>1</sub>-Adrenoceptors Independent of α<sub>2</sub>-Adrenoceptor Stimulation
《Pharmacology & Pharmacy》2017年第5期172-188,共17页Daisuke Chino Mai Naramatsu Keisuke Obara Yoshio Tanaka 
Clonidine is a classically categorized α2-adrenoceptor (α2-AR) agonist that produces vascular contractions by stimulating arterial smooth muscle α2-ARs. However, clonidine inhibits α1-AR-mediated arterial contract...
关键词：CLONIDINE α2-Adrenoceptor (α2-AR) Α1-ADRENOCEPTOR (α1-AR) RAT Aorta Relaxation 
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