GANGLIOSIDE

作品数：33被引量：60H指数：5
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相关领域：医药卫生更多>>
相关作者：邬巍陈阳辛斌徐桂云纪伟更多>>
相关机构：吉林省人民医院吉林大学第二医院吉林大学第一医院中国科学院更多>>
相关期刊：《Case Reports in Clinical Medicine》《Neural Regeneration Research》《中国药理通讯》《World Journal of Clinical Cases》更多>>
相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金安徽省自然科学基金更多>>
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Blockade of Rho-associated kinase prevents inhibition of axon regeneration of peripheral nerves induced by anti-ganglioside antibodies被引量：1
《Neural Regeneration Research》2024年第4期895-899,共5页Andrés Berardo Cristian R.Bacaglio Bárbara B.Báez Rubén Sambuelli Kazim A.Sheikh Pablo H.H.Lopez 
supported by Fondo para la Investigación Cientifica y Tecnológica(FONCy T),Argentina,grant#PICT 2015-2473(to PHHL);supported by grants from National Institute of Health/National Institute of Neurological Disorders and Stroke(NIH/NINDS,USA)(NS121621);Department of Defense,USA(Do D-CL1)(PR200530);partially financed with a fellowship for Research in Medicine from Fundación Florencio Fiorini;supported with a PhD fellowship from CONICET。
Anti-ganglioside antibodies are associated with delayed/poor clinical recovery in Guillain-Barrèsyndrome,mostly related to halted axon regeneration.Cross-linking of cell surface gangliosides by anti-ganglioside antib...
关键词：anti-ganglioside antibodies anti-glycan antibodies axon regeneration GANGLIOSIDE Guillain-Barrésyndrome nerve repair ROCK Y-27632 
Influence of ganglioside combined with methylprednisolone sodium succinate on efficacy and neurological function in patients with acute myelitis被引量：1
《World Journal of Clinical Cases》2023年第33期7972-7979,共8页Yu-Fei Sun Li-Li Liu Sha-Sha Jiang Xian-Juan Zhang Feng-Jun Liu Wan-Ming Zhang 
This study was approved by the Ethic Committee of Basic Medical College of Qingdao University(Approval No.QDWMkj-2020-012).
BACKGROUND Acute myelitis(AM)can lead to sudden sensory,motor and autonomic nervous dysfunction,which negatively affects their daily activities and quality of life,so it is necessary to explore optimization from a the...
关键词：GANGLIOSIDE Methylprednisolone sodium succinate Acute myelitis Therapeutic effect Neurological function 
Effect of Murine Nerve Growth Factor and Sodium Ganglioside on the Levels of NF-kB p56,TLR-4 and MyD88 in Hippocampus of Epileptic Rats
《Chinese Journal of Biomedical Engineering(English Edition)》2023年第3期124-130,共7页RAO Zhi-hui LIANG Hai-ying XIANG Yan-chun 
Objective:Epilepsy is a prevalent neurological condition,and NF-kB,TLR-4,and MyD88 are significant contributors to its development.Murine nerve growth factor(NGF)and monosialotetrahexosylganlioside sodium for injectio...
关键词：murine nerve growth factor(NGF) ganglioside sodium epilepsy hippocampal tissue neurons 
Role of GM3 ganglioside in the pathology of some progressive human diseases and prognostic importance of serum anti-GM3 antibodies
《BIOCELL》2021年第6期1485-1494,共10页VERA KOLYOVSKA SONYA IVANOVA DESISLAVA DRENSKA DIMITAR MASLAROV RENETA TOSHKOVA 
Glycosphingolipids(gangliosides)have been characterized as important biological molecules with a key role as regulators in many physiological processes on cellular,tissue,organ,and organism levels.The deviations in th...
关键词：Biomarkers Serum GM3 Serum anti-GM3 antibodies ELISA 
Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson’s disease被引量：9
《Acta Pharmacologica Sinica》2021年第4期518-528,共11页Yu-Lin Guo Wen-Jun Duan Dan-Hua Lu Xiao-Hui Ma Xiao-Xiao Li Zhao Li Wei Bi Hiroshi Kurihara Hai-Zhi Liu Yi-Fang Li Rong-Rong He 
the National Key Research and Development Program of China(2017YFC1700400 and 2017YFC1700404);the National Natural Science Foundation of China(81873209,81903821,81973718,81673709,and U1801284);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01Y036)and GDUPS(2019);the Guangdong Science and Technology Foundation for Distinguished Young Scholars(2017A030306004);the Natural Science Foundation of Guangdong Province(2019A1515010909);the Science and Technology Program of Guangzhou(201903010062).
GM1 ganglioside is particularly abundant in the mammalian central nervous system and has shown beneficial effects on neurodegenerative diseases.In this study,we investigated the therapeutic effect of GM1 ganglioside i...
关键词：Parkinson’s disease GM1 ganglioside Α-SYNUCLEIN AUTOPHAGY DOPAMINE 
Application of Simple Head Cooling Combined with Gangliosides in Neonatal Hypoxic-ischemic Encephalopathy
《Journal of Human Physiology》2020年第2期11-17,共7页Zhen Zhan Huanhuan Cheng Xianhong Lin Yangyang Meng Liying Dai Hong Zheng Qilian Xie 
Natural Science Foundation of Anhui Province(1808085MH308);School Research Fund Project of Anhui Medical University(2019xkj178);Hefei Science and Technology Research Project(J2018Y06)。
Objective To investigate the effect of simple head cooling combined with ganglioside therapy on neonatal hypoxic-ischemic encephalopathy(HIE)and its clinical efficacy.Methods A total of 100 children with HIE admitted ...
关键词：Hypoxic-ischemic encephalopathy NEWBORN Mild hypothermia GANGLIOSIDE Curative effect 
Physiology of gangliosides and the role of antiganglioside antibodies in human diseases被引量：10
《Cellular & Molecular Immunology》2020年第4期313-322,共10页Gianni Cutillo Anna-Helena Saariaho Seppo Meri 
supported by the Sigrid Jusélius Foundation,the Academy of Finland(292393);Helsinki University Central Hospital(TYH2018313,TYH2019311)grants.
Gangliosides are structurally and functionally polymorphic sialic acid containing glycosphingolipids that are widely distributed in the human body.They play important roles in protecting us against immune attacks,yet ...
关键词：GANGLIOSIDE Guillain-Barre syndrome COMPLEMENT NARCOLEPSY sialic acid 
Meta-analysis evaluation of the treatment of neonatal hypoxic-ischemic encephalopathy with ganglioside被引量：2
《BIOCELL》2019年第1期7-11,共5页Wen LI Junli YANG Dong ZHOU Jinghui ZHANG Qingcui ZHUO 
The efficacy and safety of ganglioside in the treatment of neonates who suffer from hypoxic-ischemic encephalopathy(HIE)needs to be fully evaluated.We searched the following databases:PubMed,ScienceDirect,LISTA,CNKI,C...
关键词：GANGLIOSIDE Hypoxic-ischemic encephalopathy META-ANALYSIS NEONATE 
Effect of ganglioside sodium on stress, neural injury degree, rebuilding related factors of neural function and coagulation index in patients with severe craniocerebral injury被引量：1
《Journal of Hainan Medical University》2019年第2期66-69,共4页Yun-Yun Cui Cheng-Gong Hu Shu-Lei Liu 
Objective:To investigate the effect of ganglioside sodium on stress, neural injury degree, rebuilding related factors of neural function and coagulation index in patients with severe craniocerebral injury.Methods: Fro...
关键词：GANGLIOSIDE sodium Nerve FUNCTION COAGULATION FUNCTION 
Ganglioside GD3 synthase(GD3S),a novel cancer drug target被引量：4
《Acta Pharmaceutica Sinica B》2018年第5期713-720,共8页Jinyi Liu Xiangjin Zheng Xiaocong Pang Li Li Jinhua Wang Cui Yang Guanhua Du 
supported by National Natural Science Foundation of China (81573454);supported by Beijing Natural Science Foundation (7172142);supported by CAMS Innovation Fund for Medical Sciences (2016-I2M-3–007)
Gangliosides are a class of important glycosphingolipids containing sialic acid that are widely distributed on the outer surface of cells and are abundantly distributed in brain tissue. Disialoganglioside with three g...
关键词：GANGLIOSIDE GD3 GD2 GD3S DRUG TARGET CANCER treatment 
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