ADHESIVE

作品数：382被引量：743H指数：12
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Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect
《Bioactive Materials》2024年第12期85-111,共27页Qinfeng Yang Guihua Liu Guanghao Chen Guo Chen Keyu Chen Lei Fan Yuesheng Tu Jialan Chen Zhanjun Shi Chuan Chen Shubo Liu Geyang Deng Xiaoqian Deng Chunhan Sun Xiaoyang Li Shuofei Yang Shaowei Zheng Bin Chen 
supported by the National Natural Science Foundation of China Youth Fund(82202662);the Guangzhou Science and Technology Program(2023A04J2314);the National Natural Science Foundation of China(12,272,164);the China Postdoctoral Science Foundation(2023M741563);the Clinical Research Startup Program of Southern Medical University by High-level University Construction Funding of Guangdong Provincial Department of Education(LC2019ZD001);the Clinical Research Program of Nanfang Hospital,Southern Medical University(2019CR016);the Project of Drug Clinical Evaluate Research of Chinese Pharmaceutical Association(CPA-Z06-ZC-2021-004);the National Natural Science Foundation of China(82370497);the Medical Scientific Research Foundation of Guangdong(A2024366);Huizhou Science Technology Project Foundation(2022CZ010423);the Macao Science and Technology Development fund(FDCT(0012/2021/AMJ,003/2022/ALC,0092/2022/A2,0144/2022/A3));the Shenzhen-Hong Kong-Macao Science and Technology Fund(Category C:SGDX20220530111203020);the Foundation of Guangdong Basic and Applied Basic Research Foundation(2022A1515140151&2022A1515140189&2023A1515140045&2022A1515140071);the National Orthopaedics Key Clinical Specialty Construction Research Foundation of Huizhou Central People’s Hospital.
Hemophilic articular cartilage damage presents a significant challenge for surgeons,characterized by recurrent intraarticular bleeding,a severe inflammatory microenvironment,and limited self-repair capability of carti...
关键词：Hemophilic articular cartilage defect Adhesive hydrogel EXOSOMES ANTI-INFLAMMATION CHONDROGENESIS 
Bioresponsive and transformable coacervate actuated by intestinal peristalsis for targeted treatment of intestinal bleeding and inflammation
《Bioactive Materials》2024年第11期627-639,共13页Yuqi Peng Xiaofen Luo Xinyu Wang c Enling Hu Ruiqi Xie Fei Lu Weiwei Ding Fangyin Dai Guangqian Lan 
Chongqing Postdoctoral International Exchange Training Program(7820100997);Fundamental Research Funds for Central Universities(Nos.SWU-XDPY22010);National College Students Innovation and Entrepreneurship Training Program(202310635114);National Natural Science Foundation of China(No.81703424);Chongqing Graduate Student Research Innovation Project(CYB21121).
Developing an oral in situ-forming hydrogel that targets the inflamed intestine to suppress bleeding ulcers and alleviate intestinal inflammation is crucial for effectively treating ulcerative colitis(UC).Here,inspire...
关键词：Intestinal ulcer bleeding Bioadhesive coacervate Intestinal peristalsis drive Bioresponsive transformation Adhesive hydrogel 
Wet tissue adhesive polymeric powder hydrogels for skeletal muscle regeneration
《Bioactive Materials》2024年第10期334-344,共11页Mingyu Lee Daun Seo Junggeon Park Sun Hong Lee Jin Jeon Woochan Kim Jangho Kim Hee Seok Yang Jae Young Lee 
supported by a grant from the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT,and Future Planning(2021M3H4A1A04092882 and 2023R1A2C2002802).
Volumetric muscle loss(VML)frequently results from traumatic incidents and can lead to severe functional disabilities.Hydrogels have been widely employed for VML tissue regeneration,which are unfortunately ineffective...
关键词：POWDER HYDROGEL Wet-adhesive Skeletal muscle regeneration 
Arginine-solubilized lipoic acid-induced β-sheets of silkfibroin-strengthened hydrogel for postoperative rehabilitation ofbreast cancer
《Bioactive Materials》2024年第10期667-682,共16页Zhuodan Zhang Yi Xia Xinyi Li Qian Zhang Yuanhao Wu Chunyan Cui Jianfeng Liu Wenguang Liu 
support for this work from the National Natural Science Foundation of China(Grant No.52233008,52303201,32301120);Program for talents in Scientific and technological Innovation of Tianjin University(Grant No.2023XQM-0047);the CAMS Innovation Fund for Medical Sciences(2023-12M-QJ-016,2022-I2M-2-003,2021-I2M-1060).
Breast cancer is the most common cancer among women worldwide, and adjuvant radiotherapy (RT) followingtumor removal is one of the most commonly used treatments for breast cancer. However, the high risk of tumorrecurr...
关键词：α-lipoic acid Adhesive hydrogel Injectable hydrogel Tumor inhibition Wound healing 
A cuttlefish ink nanoparticle-reinforced biopolymer hydrogel with robust adhesive and immunomodulatory features for treating oral ulcers in diabetes
《Bioactive Materials》2024年第9期562-581,共20页Yajing Xiang Pan Zhuge Xiaoliang Qi XinXin Ge Junbo Xiang Hangbin Xu Erya Cai Yulong Lan Xiaojing Chen Ying Li Yizuo Shi Jianliang Shen Jinsong Liu 
The financial backing for this research comes from the National Natural Science Foundation of China(82371016,21977081,82071170);the Zhejiang Provincial Natural Science Foundation for Distinguished Young Scholar(LR23C100001);the Zhejiang Provincial Science and Technology Project for Public Welfare(LGF21H140004);the Natural Science Foundation of Zhejiang Province(LQ22E030011);the Wenzhou Municipal Science and Technology Project(ZY2019009)。
Oral ulcers can be managed using a variety of biomaterials that deliver drugs or cytokines.However,many patients experience minimal benefits from certain medical treatments because of poor compliance,short retention t...
关键词：Cuttlefish ink nanoparticles Hydrogel patches Tissue adhesives Wound healing Oral ulcers 
A paintable and adhesive hydrogel cardiac patch with sustained release of ANGPTL4 for infarcted heart repair被引量：3
《Bioactive Materials》2024年第1期395-407,共13页Mingyu Lee Yong Sook Kim Junggeon Park Goeun Choe Sanghun Lee Bo Gyeong Kang Ju Hee Jun Yoonmin Shin Minchul Kim Youngkeun Ahn Jae Young Lee 
supported by a grant from the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT,and Future Planning(NRF-2021M3H4A1A04092882 and NRF-2021R1A4A3025206).
The infarcted heart undergoes irreversible pathological remodeling after reperfusion involving left ventricle dilation and excessive inflammatory reactions in the infarcted heart,frequently leading to fatal functional...
关键词：Cardiac patch HYDROGEL Angiopoietin-like 4 Myocardial infarction 
natural polymer-based bilayer adhesive skin substitute for infected burned wound healing被引量：3
《Bioactive Materials》2023年第11期177-195,共19页Mina Shahriari-Khalaji Mamoona Sattar Ran Cao Meifang Zhu 
the National Key Research and Development Program of China(2021YFA1201304/2021YFA1201300);the Fundamental Research Funds for the Central Universities(2232022D-01);the Science and Technology Commission of Shanghai Municipality,China(20DZ2254900);the Young Elite Scientists Sponsorship Program by CAST(YESS20220259).
Thermal wounds are complex and lethal with irregular shapes, risk of infection, slow healing, and large surface area. The mortality rate in patients with infected burns is twice that of non-infected burns. Developing ...
关键词：Infected burn wound Bioactive skin substitute Double cross-linked ANTI-INFLAMMATION Tissue adhesion 
Engineering self-healing adhesive hydrogels with antioxidant properties for intrauterine adhesion prevention被引量：9
《Bioactive Materials》2023年第9期82-97,共16页Luyao Feng Liqun Wang Yao Ma Wanglin Duan Sergio Martin-Saldana Ye Zhu Xianpeng Zhang Bin Zhu Chaowei Li Shibo Hu Mingjie Bao Ting Wang Yuan Zhu Fei Yang Yazhong Bu 
supported by the National Natural Science Foundation of China(52103184,81660265,81960276);Natural Science Foundation of Jiangxi Province(20224BAB206026);Key Research and Development Program of Jiangxi Province(20202BBGL73065);Funding for Basic Scientific Research and‘Young Talent Support Plan’of Xi’an Jiaotong University(xzy012022038).
Intrauterine adhesion (IUA) is the fibrosis within the uterine cavity. It is the second most common cause of female infertility, significantly affecting women’s physical and mental health. Current treatment strategie...
关键词：ADHESIVE HYDROGEL Intrauterine adhesion SELF-HEALING ANTIOXIDANT 
Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair被引量：4
《Bioactive Materials》2023年第7期273-290,共18页Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan Lei Fan Bin Yu Jian Wang Yanjun Hu 
This work was supported by the Guangzhou Science and Technology Program Key Projects(No.202002020001);Science and Technology Planning Project of Guangdong Province(No.2020A0505100039);Autonomous region science and technology branch Xinjiang project plan(No.2022E02040);Clinical Key Specialty in Ningde City,Fujian Province.
At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open fractures.However,external fixation can cause nail tract infections and is ineffective for fixing sma...
关键词：Open fracture Bone adhesive Internal fixation BACTERIOSTASIS OSTEOINDUCTION 
Wet adhesive hydrogel cardiac patch loaded with anti-oxidative,autophagy-regulating molecule capsules and MSCs for restoring infarcted myocardium被引量：1
《Bioactive Materials》2023年第3期20-31,共12页Tengling Wu Xiaoping Zhang Yang Liu Chunyan Cui Yage Sun Wenguang Liu 
National Natural Science Foundation of China(Grant No.52233008,51733006);National Key Research and Development Program(Grant No.2018YFA0703100).
Hydrogel patch-based stem cell transplantation and microenvironment-regulating drug delivery strategy is promising for the treatment of myocardial infarction(MI).However,the low retention of cells and drugs limits the...
关键词：Myocardial infarction SPONGE Hydrogel patch Wet adhesive AUTOPHAGY 
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