DEMYELINATING

作品数:41被引量:51H指数:3
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相关领域:医药卫生生物学更多>>
相关作者:丛林海王美兰汤勇吴锡芳杨一兵更多>>
相关机构:昆明医科大学更多>>
相关期刊:《Chinese Medical Journal》《Neuroimmunology and Neuroinflammation》《World Journal of Hepatology》《Stroke & Vascular Neurology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划上海市浦江人才计划项目更多>>
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White matter disease derived from vascular and demyelinating origins
《Stroke & Vascular Neurology》2024年第4期344-350,共7页Lin-Jie Zhang De-Cai Tian Li Yang Kaibin Shi Yaou Liu Yilong Wang Fu-Dong Shi 
supported in part by the National Science Foundation of China(Grants 91642205 and 81830038);funds of Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing,China;funded by Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-004A).
Damage or microstructural alterations of the white matter can cause dysfunction of the intrinsic neural networks in a condition termed as white matter disease(WMD).Frequently detected on brain computed tomography and ...
关键词:DIAGNOSIS MYELIN alterations 
Serum LDL Promotes Microglial Activation and Exacerbates Demyelinating Injury in Neuromyelitis Optica Spectrum Disorder被引量:1
《Neuroscience Bulletin》2024年第8期1104-1114,共11页Man Chen Yun‑Hui Chu Wen‑Xiang Yu Yun‑Fan You Yue Tang Xiao‑Wei Pang Hang Zhang Ke Shang Gang Deng Luo‑Qi Zhou Sheng Yang Wei Wang Jun Xiao Dai‑Shi Tian Chuan Qin 
supported by the National Natural Science Foundation of China(82371404,82271341,82071380,and 81873743);the Knowledge Innovation Program of Wuhan Shuguang Project(2022020801020454);the Tongji Hospital Foundation for Excellent Young Scientists(2020YQ06).
Neuromyelitis optica spectrum disorder(NMOSD)is an autoimmune inflammatory demyelinating disease of the central nervous system(CNS)accompanied by blood-brain barrier(BBB)disruption.Dysfunction in microglial lipid meta...
关键词:Neuromyelitis optica spectrum disorder Low-density lipoprotein MICROGLIA 
Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease被引量:2
《Neural Regeneration Research》2023年第9期1931-1939,共9页Nadège Hertzog Claire Jacob 
supported by the Deutsche Forschungsgemeinshaft (to CJ)。
Schwann cells,the myelinating glia of the peripheral nervous system,wrap axons multiple times to build their myelin sheath.Myelin is of paramount importance for axonal integrity and fast axon potential propagation.How...
关键词:Charcot-Marie-Tooth disease rodent models emerging treatments demyelination and dysmyelination endoplasmic reticulum stress gene therapy MYELIN repair Schwann cells unfolded protein response 
X-linked Charcot-Marie-Tooth disease after SARS-CoV-2 vaccination mimicked stroke-like episodes: A case report
《World Journal of Clinical Cases》2023年第2期464-471,共8页Qiang Zhang Yang Wang Run-Tao Bai Bao-Rong Lian Yu Zhang Li-Ming Cao 
Supported by Shenzhen Science and Technology Project,No. SGLH20180628161804465;The Clinical Research Project of The First Affiliated Hospital of Shenzhen University,No. 20203357035 and No. 20223357021。
BACKGROUND Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) vaccinations have been administered worldwide, with occasional reports of associated neurological complications. Specifically, the impact of vacci...
关键词:X-linked Charcot-Marie-Tooth disease SARS-CoV-2 vaccination Stroke-like episodes Reversible splenial lesion syndrome Demyelinating leukoencephalopathy Case report 
Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics被引量:1
《Virologica Sinica》2021年第5期1006-1026,共21页Benjamin Charvet Justine Pierquin Joanna Brunel Rianne Gorter Christophe Que´tard Branka Horvat Sandra Amor Jacques Portoukalian Herve´Perron 
supported by GeNeuro SA.
In multiple sclerosis(MS),human endogenous retrovirus W family(HERV-W)envelope protein,pHERV-W ENV,limits remyelination and induces microglia-mediated neurodegeneration.To better understand its role,we examined the so...
关键词:Multiple sclerosis(MS) Brain Antigen HERV-W ENVELOPE Endogenous retrovirus MSRV-ENV SYNCYTIN Demyelination Lipids GLYCOLIPIDS Sulfatides Oligomer HEXAMER 
The clinical application of critical flicker fusion frequency in demyelinating optic neuritis
《Advances in Ophthalmology Practice and Research》2021年第2期5-9,共5页Junxia Fu Yongping Wang Shaoying Tan Guangcan Xu Huanfen Zhou Quangang Xu Shihui Wei 
National Key Research and Development Program(2018YFE0113900).
Purpose:To investigate the application of critical flicker fusion frequency(CFF)in demyelinating optic neuritis(DON).Methods:A cross-sectional study.A total of 127 eyes in 69 DON patients and 63 eyes in 33 healthy con...
关键词:Critical flicker fusion frequency Demyelinating optic neuritis 
Differences in the involved sites among different types of demyelinating optic neuritis in traditional MRI examination:A systematic review and meta-analysis
《Advances in Ophthalmology Practice and Research》2021年第2期20-27,共8页Yongping Wang Junxia Fu Honglu Song Quangang Xu Huanfen Zhou Shihui Wei 
the National Key Research and Development Program(2018YFE0113900).
Background:Magnetic resonance imaging(MRI)plays a significant role in assessing optic neuropathy and providing more detailed information about the lesion of the visual pathway to help differentiate optic neuritis from...
关键词:Demyelinating optic neuritis Magnetic resonance imaging A systemic review META-ANALYSIS 
TAPP1 Represses the Differentiation of Oligodendrocyte and its Deficiency Accelerates Myelin Regeneration after Demyelinating Injuries被引量:2
《Neuroscience Bulletin》2021年第3期385-388,共4页Ruyi Mei Jiaying Fu Chunxia Jiang Junlin Yang Kang Zheng Aifen Yang Mengsheng Qiu Xiaofeng Zhao 
supported by the Natural Science Foundation of Zhejiang Province,China(LY17C090006,LQ16C090004,and LY18H090014)。
Dear Editor,Myelin,the lipid-rich insulation that supports the integrity of axons,enables rapid conduction of nerve impulses and information flow to distant brain areas[1].Oligodendrocytes(OLs)are glial cells that mye...
关键词:insulation conduction enable 
Neurofilament light chain in demyelinating conditions of the central nervous system: a promising biomarker
《Neuroimmunology and Neuroinflammation》2021年第1期1-13,共13页Silvia Bozzetti Sergio Ferrari Alberto Gajofatto Sara Mariotto 
Neurofilaments are the major structural proteins of the neuronal cytoskeleton and are classified according to molecular weight into heavy,intermediate,and light chains.They are released into the interstitial fluid and...
关键词:Neurofilament light chain multiple sclerosis clinically isolated syndromes radiologically isolated syndrome neuromyelitis optica spectrum disorders myelin oligodendrocyte glycoprotein AQUAPORIN-4 
Demyelinating polyneuropathy and lymphoplasmacytic lymphoma coexisting in 36-year-old man:A case report
《World Journal of Clinical Cases》2020年第12期2566-2573,共8页Lesia Rozlucka Elzbieta Semik-Grabarczyk Marta Pietrukaniec Agnieszka Zak-Golab Malgorzata Grabarczyk Sebastian Grosicki Michal Holecki 
BACKGROUND Lymphoplasmacytic lymphoma is a rare non-Hodgkin’s lymphoma,occurring mostly in the elderly.It develops slowly and leads to malignant proliferation of lymphoid line cells in the bone marrow,lymph nodes and...
关键词:Lymphoplasmacytic lymphoma Chronic inflammatory demyelinating polyneuropathy POLYNEUROPATHY Paraneoplastic neuropathy AUTOIMMUNITY Case report 
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