METHYLPREDNISOLONE

作品数：98被引量：353H指数：10
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相关机构：台湾大学宁波市第二医院第二军医大学解放军第98医院更多>>
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  • 期刊=Neural Regeneration Researchx
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Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study被引量：5
《Neural Regeneration Research》2024年第5期1126-1132,共7页Hengxing Zhou Yongfu Lou Lingxiao Chen Yi Kang Lu Liu Zhiwei Cai David BAnderson Wei Wang Chi Zhang Jinghua Wang Guangzhi Ning Yanzheng Gao Baorong He Wenyuan Ding Yisheng Wang Wei Mei Yueming Song Yue Zhou Maosheng Xia Huan Wang Jie Zhao Guoyong Yin Tao Zhang Feng Jing Rusen Zhu Bin Meng Li Duan Zhongmin Zhang Desheng Wu Zhengdong Cai Lin Huang Zhanhai Yin Kainan Li Shibao Lu Shiqing Feng 
supported by the National Key Research and Development Project,No.2019YFA0112100(to SF).
Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic ...
关键词：China clinical features COSTS EPIDEMIOLOGY methylprednisolone sodium succinate METHYLPREDNISOLONE retrospective study traumatic spinal cord injury TREATMENT 
Effects of decompression joint Governor Vessel electro-acupuncture on rats with acute upper cervical spinal cord injury被引量：8
《Neural Regeneration Research》2018年第7期1241-1246,共6页Yan-Lei Wang Ying-Na Qi Wei Wang Chun-Ke Dong Ping Yi Feng Yang Xiang-Sheng Tang Ming-Sheng Tan 
supported by the Capital Characteristic Clinical Application Research Projects of Beijing Municipal Science and Technology Plan of China,No.Z16110000516009
Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatme...
关键词：nerve regeneration acute spinal cord injury decompression Governor Vessel electroacupuncture platelet-activating factor apoptosis methylprednisolone caspase family upper cervical spine animal model Basso Beattie and Bresnahan locomotor scale neural regeneration 
Does vitamin C have the ability to augment the therapeutic effect of bone marrow-derived mesenchymal stem cells on spinal cord injury？被引量：2
《Neural Regeneration Research》2017年第12期2050-2058,共9页Nesrine Salem Mohamed Y.Salem Mohammed M.Elmaghrabi Moataz A.Elawady Mona A.Elawady Dina Sabry Ashraf Shamaa Abdel-Haleem H.Elkasapy Noha Ibrhim Azza Elamir 
funded by Project Management Unit,Banha University,Banha,Egypt
Methylprednisolone（MP） is currently the only drug confirmed to exhibit a neuroprotective effect on acute spinal cord injury（SCI）. Vitamin C（VC） is a natural water-soluble antioxidant that exerts neuroprotective ...
关键词：nerve regeneration spinal cord injury vitamin C METHYLPREDNISOLONE bone marrow mesenchymalstern cells locotmotor neural regeneration 
Methotrexate combined with methylprednisolone for the recovery of motor function and differential gene expression in rats with spinal cord injury被引量：6
《Neural Regeneration Research》2017年第9期1507-1518,共12页Jian-tao Liu Si Zhang Bing Gu Hua-nan Li Shuo-yu Wang Shui-yin Zhang 
supported by the National Natural Science Foundation of China,No.30960448;the Natural Science Foundation of Jiangxi Province,No.20142BAB205023;the Ph.D.Start-up Fund of Natural Science Foundation of Jiangxi Science&Technology Normal University in China,No.3000990122
Methylprednisolone is a commonly used drug for the treatment of spinal cord injury, but high doses of methylprednisolone can increase the incidence of infectious diseases. Methotrexate has anti-inflammatory activity a...
关键词：nerve regeneration spinal cord injury METHOTREXATE METHYLPREDNISOLONE GAIT gene expression profile inflammation oxidative stress apoptosis nerve repair Solexa gene sequencing secondary lesion neural regeneration 
Methylprednisolone promotes recovery of neurological function after spinal cord injury： association with Wnt/β-catenin signaling pathway activation被引量：12
《Neural Regeneration Research》2016年第11期1816-1823,共8页Gong-biao Lu Fu-wen Niu Ying-chun Zhang Lin DU Zhi-yuan Liang Yuan Gao Ting-zhen Yan Zhi-kui Nie Kai Gao 
supported by the National Natural Science Foundation of China,No.81471854
Some studies have indicated that the Wnt/β-catenin signaling pathway is activated following spinal cord injury, and expression levels of specific proteins, including low-density lipoprotein receptor related protein-6...
关键词：nerve regeneration spinal cord injury NEUROPROTECTION METHYLPREDNISOLONE apoptosis locomotor function caspase-3 caspase- 9 BAX Bcl-2 neural regeneration 
Combination of methylprednisolone and rosiglitazone promotes recovery of neurological function after spinal cord injury被引量：4
《Neural Regeneration Research》2016年第10期1678-1684,共7页Xi-gong Li Xiang-jin Lin Jun-hua Du San-zhong Xu Xian-feng Lou Zhong Chen 
Methylprednisolone exhibits anti-inflammatory antioxidant properties, and rosiglitazone acts as an anti-inflammatory and antioxidant by activating peroxisome proliferator-activated receptor-y in the spinal cord. Methy...
关键词：nerve regeneration spinal cord injury methylprednisotone ROSIGLITAZONE INFLAMMATION drug therapy anti-inflammatory agents functional recovery neural regeneration 
Methylprednisolone for acute spinal cord injury: an increasingly philosophical debate被引量：11
《Neural Regeneration Research》2016年第6期882-885,共4页Christian A.Bowers Bornali Kundu Gregory W.J.Hawryluk 
Following publication of NASCIS Ⅱ, methylprednisolone sodium succinate（MPSS） was hailed as a breakthrough for patients with acute spinal cord injury（SCI）. MPSS use for SCI has since become very controversial and ...
关键词：debate autonomy opinion argue break informed administration translational historical preference 
Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis被引量：2
《Neural Regeneration Research》2016年第5期823-828,共6页Wei Gao Shu-rui Chen Meng-yao Wu Kai Gao Yuan-long Li Hong-yu Wang Chen-yuan Li Hong Li 
supported by the National Natural Science Foundation of China,No.81171799,81471854;the Science and Technology Research Project of Education Department of Liaoning Province of China,No.L2013333;the"College Students’Science and Technology Innovation Project"of Liaoning Medical University Principal Fund-Aohong Boze Fund of China,No.2014D08;the Liaoning Medical University Principal Fund-Aohong Boze Graduate Student Science Research Innovation Fund,No.AH2014017
Methylprednisolone markedly reduces autophagy and apoptosis after secondary spinal cord injury. Here, we investigated whether pretreatment of cells with methylprednisolone would protect neuron-like cells from subseque...
关键词：nerve regeneration spinal cord injury METHYLPREDNISOLONE oxidative stress N2a cells AUTOPHAGY light chain 3B BECLIN-1 APOPTOSIS NEUROPROTECTION H2O2 neural regeneration 
Methylprednisolone microsphere sustained-release membrane inhibits scar formation at the site of peripheral nerve lesion被引量：5
《Neural Regeneration Research》2016年第5期835-841,共7页Qiang Li Teng Li Xiang-chang Cao De-qing Luo Ke-jian Lian 
supported by the Technology Fund of Zhangzhou City in China,No.Z2010086
Corticosteroids are widely used for the treatment of acute central nervous system injury. However, their bioactivity is limited by their short half-life. Sustained release of glucocorticoids can prolong their efficacy...
关键词：nerve regeneration peripheral nerve injury nanometer SCAR methylprenisolone sustained-release membrane biological agents peripheral nerve neural regeneration 
Methylprednisolone inhibits Nogo-A protein expression after acute spinal cord injury被引量：3
《Neural Regeneration Research》2013年第5期404-409,共6页Zhaozong Fu Hai Lu Jianming Jiang Hui Jiang Zhaofei Zhang 
Oligodendrocyte-produced Nogo-A has been shown to inhibit axonal regeneration. Methylprednisolone plays an effective role in treating spinal cord injury, but the effect of methylprednisolone on Nogo-A in the injured s...
关键词：neural regeneration spinal cord injury METHYLPREDNISOLONE NOGO-A OLIGODENDROCYTE spJnal cord pathology myelonecrosis weight-drop contusion photographs-containing paper NEUROREGENERATION 
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