N-METHYLASPARTATE

作品数:5被引量:18H指数:3
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相关作者:刘惠芬杨国栋周文华顾均曾因明更多>>
相关机构:宁波戒毒研究中心徐州医学院附属医院江苏省麻醉学重点实验室更多>>
相关期刊:《Acta Pharmacologica Sinica》《Cancer Biology & Medicine》更多>>
相关基金:国家自然科学基金北京市自然科学基金更多>>
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Effect of flupirtine on the growth and viability of U373 malignant glioma cells
《Cancer Biology & Medicine》2013年第3期142-147,共6页Elango Panchanathan Gnanasambandan Ramanathan Bhaskar Venkata Kameswara Subrahmanya Lakkakula 
supported by an intramural grant from Sri Ramachandra University,Chennai
Objective: Flupirtine is a non-opioid analgesic without antipyretic or antiphlogistic properties but with favorable tolerability in humans. "Ibis analgesic also exhibits neuroprotective activities. Furthermore, flup...
关键词:FLUPIRTINE N-METHYLASPARTATE ANALGESICS GLIOMA 
ONO-1078 reduces NMDA-induced brain injury and vascular cell adhesion molecule-1 expression in rats被引量:12
《Acta Pharmacologica Sinica》2005年第4期435-440,共6页Li-huiZHANG Er-qingWEI 
Project supported by the National Natural Science Foundation of China(No 30271498).
Aim:To determine whether ONO-1078 (pranlukast),a potent cysteinyl leukotriene receptor 1 (CysLTI) antagonist,has an effect on N-methyl-D-aspartate (NMDA)- induced brain injury and vascular cell adhesion molecule-1 (VC...
关键词:leukotriene antagonists PRANLUKAST N-METHYLASPARTATE vascular cell adhesion molecule-1 NEUROTOXICITY brain injuries 
Moclobemide up-regulates proliferation of hippocarnpal progenitor cells in chronically stressed mice被引量:3
《Acta Pharmacologica Sinica》2004年第11期1408-1412,共5页Yun-fengLI You-zhiZHANG Yan-qinLIU Heng-linWANG LiYUAN Zhi-puLUO 
Project supported by the National Natural Science Foundation of China(No30300419)Natural Science Foundation of Beijing City(No7042052).
AIM: To explore the action mechanism of antidepressants. METHODS: The PC12 cell proliferation was detected by flow cytometry,. The proliferation of hippocampal progenitor cells and level of brain-derived neurotrophic ...
关键词:antidepressants MOCLOBEMIDE NEUROGENESIS STRESS brain-derived neurotrophic factor N-METHYLASPARTATE 
Activation and involvement of JNK1/2 in hydrogen peroxideinduced neurotoxicity in cultured rat cortical neurons被引量:3
《Acta Pharmacologica Sinica》2004年第5期630-636,共7页WeiWANG CanGAO Xiao-yuHOU YongLIU Yan-yanZONG Guang-yiZHANG 
The present study was supported by grants from the Educa-tion Departmental Natural Science Research Funds of JiangsuProvince of China (No 99KJB180002; 99KJD180004) and theNational Natural Science Foundation of China (No 39770177).2
AIM: To investigate the role of c-Jun N-terminal protein kinase 1 and 2 (JNK1/2) and the main signal pathway forits activation in hydrogen peroxide (H2O2) induced apoptotic-like cortical cell death. METHODS: Using th...
关键词:c-Jun N-terminal protein kinase calcium N-methylaspartate receptors hydrogen peroxide SIGNALTRANSDUCTION apoptosis cerebral cortex 
NO mediated increase of Fos protein and NMDA_(1A) R mRNA expression in rat spinal cord during morphine withdrawal
《Acta Pharmacologica Sinica》2001年第6期29-35,共7页曹君利 曾因明 张励才 顾均 刘惠芬 周文华 杨国栋 
AIM: To investigate the effects of nitric oxide (NO) on activation of the rat spinal cord neurons during naloxone-precipitated morphine withdrawal. METHODS: Fos immunocytochemistry, NADPH-d histochemistry, Fos/ NADPH-...
关键词:MORPHINE substance withdrawal syn-drome nitric oxide proto-oncogene proteins c-fos spinal cord N-METHYLASPARTATE 
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