Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences,Grant/Award Numbers:2021-I2M-1-052,2017-I2M-1-007;National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases,Grant/Award Number:21025;National Natural Science Foundation of China,Grant/Award Numbers:82371796,81871575。
Despite recent advances in extrusion bioprinting of cell-laden hydrogels,using nat-urally derived bioinks to biofabricate complex elastic tissues with both satisfying biological functionalities and superior mechanical...
Background:Collagen peptides(CP),including tripeptides and elastin peptides(EP),are known for their in vitro and in vivo anti-skin aging effects.Despite positive results in animal models,the combination effects of CP ...
sponsored by the National Key R&D Program of China(2018YFD0901102);the Fund of State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products(ZS20190105);the Natural Foundation of Zhejiang Province(LQ22D060002);the Cooperative Project of Vigour Health Products Co.,Ltd,Shenzhen;the K.C.Wong Magna Fund of Ningbo University.
Background:Our previous study demonstrated that a dietary intervention with skipjack tuna(Katsuwonus pelamis)elastin peptides alleviated adjuvant-induced arthritis(AIA)and affected the gut microbiota of AIA mice.How-e...
The Ethical Review Committee of Ghent University Hos-pital approved this prospective study(Belgian registration number B670201733327);The trial was registered on cli nicaltrials.gov and received the following registration code:NCT01033604.
Background:Absence of almost the entire reticular dermal layer is inherent to the use of autologous split-thickness skin grafting(STSG)to close full-thickness wounds,often resulting in hypertrophic scars and contractu...
support:R01EB022018,R15HL140503,T32 HL134613 from NIH,UT STARS.
Cardiac extracellular matrices(ECM)play crucial functional roles in cardiac biomechanics.Previous studies have mainly focused on collagen,the major structural ECM in heart wall.The role of elastin in cardiac mechanics...
Photoaging and carcinogenesis are facilitated by oxidative stress,inflammation,angiogenesis,and extracellular matrix(ECM)remodeling.Oxidative effects include DNA damage,membrane oxidation,lipid peroxidation,and altera...
from National Key R&D Program of China(grant no.2018YFA0902600);the Scientific Instrument Developing Project of the Chinese Academy of Sciences(grant no.ZDKYYQ20180001);the Jilin Province Science Fund for Excellent Young Scholars(20190103072JH),K.C.Wong Education Foundation(grant no.GJTD-2018-09);and the National Natural Science Foundation of China(grant nos.21704099,21877104,and 21834007)and the Cure Alzheimer’s Fund.
Alzheimer’s disease(AD)is a neurodegenerative disorder,and the etiology of AD has not been completely elucidated.It remains unknown how the components from the brain’s extracellular matrix(ECM),particularly fibrous ...
The extracellular matrix(ECM)occupies the space between cell and cell,and serves as a sort of intranet which connects the whole organism.Current research is focused on the ECM and,it is now possible to develop increas...