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ANTITUMOR: 作品数：470被引量：1206H指数：15; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：明艳林陈良华刘韶松齐宪荣李润涛更多>>; 相关机构：北京大学天津医科大学中国药科大学福建省亚热带植物研究所更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

Synthesis, Crystal Structure and Antitumor Activities of N-(2-(2-hydroxy-2-phenylacetyl)phenyl)cinnamamide: 《Chinese Journal of Structural Chemistry》2019年第10期1701-1706,1610,共7页王芳周学浩肖新生贾国凯; supported by the construct program of applied characteristic discipline in Hunan University of Science and Engineering,Research Learning and Innovative Experimental Program for College Students of Hunan University of Science and Engineering(No.[2018]32-51);the opening project of key laboratory of comprehensive utilization of advantage plants resources in Hunan south,Hunan university of science and engineering(No.XNZW17C04,XNZW17C05);the Planned Science and Technology Project of Hunan Yongzhou,China(No.2018ZD15); The title compound N-(2-(2-hydroxy-2-phenylacetyl)phenyl)cinnamamide(C23H19NO3,Mr=357.39)has been synthesized with 2-iodoaniline and ethynylbenzene as starting materials,and its crystal structure was determined by ^1H...; 关键词：SYNTHESIS CRYSTAL structure ANTITUMOR activity

Synthesis, Structure and Biological Activity of 2-[2-(4-Fluorobenzylidene)hydrazinyl]-4-(1-methyl-1H-indol-3-yl)thieno[3,2-d]pyrimidine被引量：3: 《Chinese Journal of Structural Chemistry》2019年第9期1530-1536,共7页SHI Jian-Tao GONG Yi-Lin LI Jun WANG Yang CHEN Ye DING Shi LIU Ju; Supported by the projects of Shenyang Science&Technology(18-013-0-03);the Youth National Natural Science Foundation of China(21807055); The title compound 2-[2-(4-fluorobenzylidene)hydrazinyl]-4-(1-methyl-1 H-indol-3-yl)thieno[3,2-d] pyrimidine(8) was synthesized by the condensation of 4-fluorobenzaldehyde(7) with 2-hydrazinyl-4-(1-methyl-1 H-indol-3-...; 关键词：thieno[3 2-d] PYRIMIDINE SYNTHESIS X-ray DIFFRACTION ANTITUMOR activity

Synthesis, Crystal Structure and Antitumor Activity of a Na(Ⅰ) Coordination Polymer Based on 2-Propyl-4,5-imidazoledicarboxylic Acid and 1,10-Phenanthroline Ligands被引量：1: 《Chinese Journal of Structural Chemistry》2019年第7期1079-1085,共7页TAI Xi-Shi ZHOU Xiao-Jing LIU Li-Li; supported by the National Natural Science Foundation of China(No.21171132);the Project of Shandong Province Higher Educational Science and Technology Program(J14LC01);Science Foundation of Weifang; A new Na(I) coordination polymer,[Na2(Hpimdc)(H2 pimdc)(phen)2]n(1), has been synthesized by the reaction of NaOH with 2-propyl-4,5-imidazoledicarboxylic acid(H3 pimdc)and 1,10-phenanthroline(phen). The Na(I) coordina...; 关键词：2-propyl-4 5-imidazoledicarboxylic acid Na(Ⅰ) coordination polymer SYNTHESIS crystal structure ANTITUMOR activity

Synthesis and antitumor, antityrosinase, and antiplatelet aggregation activities of xanthone被引量：1: 《Journal of Chinese Pharmaceutical Sciences》2019年第4期247-256,共10页周北斗王欣翁智敏黄堡城马泽通于博阮丽琴胡栋宝; Fujian Provincial Department of Science and Technology(Grant No.2018Y0072); In the present study, five fluorine substituted and three chlorine substituted 1,3-dihydroxyxanthones were synthesized in one step.The yields ranged from 48% to 72%.Among them, compounds 12 and 15–18 were reported fo...; 关键词：XANTHONE SYNTHESIS ANTITUMOR Antityrosinase ANTIPLATELET AGGREGATION

Synthesis and Determination of Antitumor Activity of Jacaranone and Synthetic Analogs: 《International Journal of Organic Chemistry》2018年第1期115-124,共10页María L. Arias Eugenia Corrales Rebeca Poveda Jorge A. Cabezas; Natural product jacaranone, 1, and three analog derivatives were synthesized and their apoptotic and necrotic activity against four cancer cell lines was tested. One of these derivatives 7, was more active than the na...; 关键词：Jacaranone Jacaranone SYNTHETIC ANALOGS ANTITUMOR ACTIVITY

Synthesis,Crystal Structure and Antitumor Activity of a New 3H-Phenanthro-[2,1-d]imidazole Derivative of Dehydroabietic Acid被引量：3: 《Chinese Journal of Structural Chemistry》2015年第9期1440-1445,共6页谷文苗婷婷王石发郝云张康平金晓燕; Project supported by the National Natural Science Foundation of China(31000273);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD); The title compound （CI9H24BrN302, 3） was synthesized from dehydroabietic acid and its crystal structure was determined by single-crystal X-ray diffraction. The compound is of monoclinic system, slSace group C2 with ...; 关键词：dehydroabietic acid 3H-phenanthro[2 1-d]imidazole crystal structure ANTITUMOR

Design, Synthesis and Antitumor Activity of Pyrrolopyrazinone-chalcone Hybrids: 《Chemical Research in Chinese Universities》2014年第4期624-631,共8页MENG Ying ZHANG Hongwei LIU Zehua ZENG Shanchao SUN Chiyu ZHANG Lijuan ZHAO Mingming WANG Guan JIANG Mengying SHI Wei SONG Hongrui; A series of pyrrolopyrazinone-chalcone hybrids（12a-12q） was designed,synthesized and screened for their antitumor activity against SKOV-3,A549 and HeLa cell lines in vitro.Compared with the pyrrolopyrazinone（10a） ...; 关键词：Pyrrolopyrazinone-chalcone hybrid ANTITUMOR Marine sponge Combination principle

Synthesis and Antitumor Activity of a New 7-Azaindole Derivative: 《Chemical Research in Chinese Universities》2014年第3期420-424,共5页ZHANG Peng SUI Dayun XU Huali SUN Weilun YU Xiaofeng QU Shaochun HU Jianbing WU Yi WANG Yingshi; We designed and synthesized a 7-azaindole derivative（TH1082）, which was characterized by 1^H NMR and 13^C-NMR. We investigated its antitumor effects on human melanoma A375 cells, human liver cancer SMMC cells and hu...; 关键词：7-Azaindole ANTITUMOR APOPTOSIS

Synthesis and Antitumor Activity Evaluation of Pyrimidine Analogues Bearing Urea Moiety: 《Chinese Journal of Chemistry》2014年第5期443-447,共5页Kunpeng Shao Xuyao Zhang Xiaosong Zhang Dengqi Xue Liying Ma Qiurong Zhang Hongmin Liu; This work was supported by the National Natural Science Foundation of China(Nos.81172937,U1204206);China Postdoctoral Science Foundation(Nos.20100480857,201104402);New Teachers’Fund for Doctor Stations,Ministry of Education(No.20114101120013).; A series of 4-anilino-6-phenylpyrimidines containing urea moiety were synthesized and the structures of all products were confirmed by^(1)H NMR,^(13)C NMR and HRMS.The antiproliferative activities of these compounds w...; 关键词：SYNTHESIS PYRIMIDINE UREA ANTITUMOR

Synthesis and biological evaluation of new pyrrolopyrazinone compounds as potential antitumor agents: 《Chinese Chemical Letters》2013年第7期619-621,共3页Ying Meng Guan Wang Yue Li Kuan Hou Yue Yuan Li-Juan Zhang Hong-Rui Song Wei Shi; A series of pyrrolo[1,2-a]pyrazinone compounds （Sa-gf） were synthesized, and their cytotoxic activity against SKOV-3, A549, HeLa cells in vitro were evaluated by the MTF method. Some of the compounds showed potentia...; 关键词：Pyrrolopyrazinone Antitumor Synthesis

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