supported by a University of Manitoba Graduate Fellowship;Graduate Enhancement of Tricouncil Supplement (GETS);Hillary Kaufman Lerner Memorial Funds;supported by the grants from Multiple Sclerosis Society of Canada (EGDI-2936, EGDI-3742);the Canadian Institute of Health Research (133721 and 156218)
Multiple sclerosis(MS)is a chronic immune-mediated disorder of the central nervous system(CNS)that causes focal demyelinating lesions,followed by axonal and neuronal degeneration.Several genetic and environmental fact...
Neuregulin-1 (NRG1) is a well known growth factor playing contradictory roles in myelination depending on the existing isoform. Transmembrane NRG1 acts as a promyelinating factor, while the soluble isoform inhibits my...
supported by a grant from the National Key Basic Research Development Program,the“973”Program,No.2012CB518604;the National Natural Science Foundation of China,No.81260052;the Natural Science Foundation of Hubei Province,No.2014CKB497,2014BKB075,and 2015BKA339;the Natural Science Foundation of Henan Province of China,No.201602262
Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction (MI). Increasing evidence indicates that neuregulin-1 (NRG-1) improves cardiac function following ...
supported by grants awarded to SKA from the Canadian Institutes of Health Research(CIHR,No.MOP 133721);the Canadian Paraplegic Association of Manitoba,and the Manitoba Paraplegic Foundation;supported by a fellowship from Research Manitoba and Rick Hansen Institute
Spinal cord injury (SCI) results in a dysregulated microenvi- ronment that is largely driven by the immediate and robust response of resident astrocytes and microglia (Filous and Silver, 2016).
supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542206;the National Natural Science Foundation of China,No.81201389,30973052;Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China,No.IRT13051
Neuregulin-1 type Ⅲ is a key regulator in Schwann cell proliferation, committing to a myelinat- ing fate and regulating myelin sheath thickness. However, the expression pattern of neuregulin- 1 type III in the periph...
a Grant from Science and Technology Commission of Shanghai,No.06ZR14108
Peripheral nerve injury in humans often leads to permanent functional deficits. Schwann cells play an important role in the recovery of peripheral nerve injury by ensheathing axons and providing various neurotrophic f...
BACKGROUND: Recent studies have paid much attention to the newly found neuregulin-1, which might be closely linked to the molecular genetics of schizophrenia. OBJECTIVE: To investigate the association of neuregulin-...