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supported by grants from the National Natural Science Foundation of China 82130071,82072516(Kanglai Tang);Sports Injury Repair and Reconstruction Research Innovative Team 41CZDH,Personalized Training Program of Leading Talent Training Object 414ZB2(Kanglai Tang);National Key R&D Program of China 2021YFC2401300(Lin Guo);National Natural Science Foundation of China 82173134(Hongming Miao);The Funding of Jinfeng Laboratory and Chongqing Outstanding Youth Fund CSTB2022NSCQ-JQX0010(Hongming Miao);NIH research grants R01AR062207,R01AR061484,R01AR076900,R01NS103931(Chuanju Liu);NIH research grants 1S10OD010582-01A1(Beatrix Ueberheide).
Metabolites can double as a signaling modality that initiates physiological adaptations.Metabolism,a chemical language encoding biological information,has been recognized as a powerful principle directing inflammatory...
upported by the National Key Research and Development Program of China,“Physiological basis and regulation of fruit tree quality and high yield”(2019YFD1000103);a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
Soluble sugar and organic acids are key determinants of fruit organoleptic quality and directly affect the commodity value and economic returns of fruit crops.We performed whole-genome sequencing of the apple varietie...
This work was supported by the National Natural Science Foundation of China(32272695 and 31972398 to X.S.);the National Key Research and Development Program of China(2019YFD1000300);the National Natural Science Foundation of China(31960591 to N.S.);the Max-Planck Society and European Union’s Horizon 2020 research and innovation programme,project PlantaSYST(SGA-CSA No.664621 and No.739582 under FPA No.664620);the China Agriculture Research System of MOF and MARA(CARS-23);the 111 Project of Ministry of Education of P.R.C.(B17043).
Central metabolism produces carbohydrates and amino acids that are tightly correlated to plant growth and thereby crop productivity.Malate is reported to link mitochondrial respiratory metabolism with cytosolic biosyn...
supported by grants from the National Key Research and Development Program of China(2022YFD2100102);National Natural Science Foundation of China(32122080,31972375);Shandong Province(ZR2020YQ25).
As the main organic acid in fruits,malate is produced in the cytoplasm and is then transported into the vacuole.It accumulates by vacuolar proton pumps,transporters,and channels,affecting the taste and flavor of fruit...
the National Key Research Development Program of China(2022YFA0912100);the National Natural Science Foundation of China(NFSC;32070272);the major demonstration project"The Open Competition"for seed industry science and technology innovation in Inner Mongolia(2022JBGS0016).
Nodulation is an energy-expensive behavior driven by legumes by providing carbon sources to bacteroids and obtaining nitrogen sources in return.The energy sensor sucrose nonfermenting 1-related protein kinase 1(SnRK1)...
supported by the National Key Research and Development Program of China(2022YFD1900700);the National Natural Science Foundation of China(32072663);the Opening Project of Guangdong Provincial Key Laboratory of Quality&Safety Risk Assessment for Agroproducts(SZKF202201)。
Inorganic phosphate(Pi)is often limited in soils due to precipitation with iron(Fe)and aluminum(Al).To scavenge heterogeneously distributed phosphorus(P)resources,plants have evolved a local Pi signaling pathway that ...
financially supported by National Natural Science Foundation of China,China(Grant No.81872768,81673323,82003630);Scientific Research Fund of Liaoning Province Education Department,Liaoning(LJKZ0949);Special Fund of Research Institute of Drug Regulatory Science Research Shenyang Pharmaceutical University,Liaoning(2021jgkx010);State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources(Guangxi Normal University),Guangxi(CMEMR2022-B04)。
Objective: To study the protective activities of the dietary malate esters derivatives of Bletilla striata against SiO_(2)nanoparticles-induced A549 cell lines and its mechanism action.Methods: The components were iso...
supported by grants from the Ministry of Science and Technology of the People's Republic of China(2020YFA0803300,Z.L.);the National Natural Science Foundation of China(82188102,82030074,Z.L.;81902423,D.G.);ZhejiangNatural ScienceFoundation Key Project(LD21H160003,Z.L.);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2019R01001,Z.L.).Z.L.is the Kuancheng Wang Distinguished Chair.
The tricarboxylic acid(TCA)cycle identified in 1937 by Hans Adolf Krebs and William Arthur Johnson(also known as the Krebs cycle or citric acid cycle)is a central route for oxidative metabolism to generate cellular en...
This study was funded by the National Natural Science Foundation of China(U1804103,31101188);Sponsored by State Key Laboratory of Cotton Biology Open Fund(CB2020A10).
Aluminum-activated malate transporters(ALMT)are widely involved in plant growth and metabolic processes,including adaptation to acid soils,guard cell regulation,anion homeostasis,and seed development.Although ALMT gen...
supported in part by the China Natural Sciences Foundation projects (No. 81772947)。
Objective: α-ketoglutarate(α-KG) is the substrate to hydroxylate collagen and hypoxia-inducible factor-1α(HIF-1α), which are important for cancer metastasis. Previous studies have shown that the upregulation of co...