DITERPENOIDS

作品数:159被引量:213H指数:6
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相关领域:理学医药卫生更多>>
相关作者:皮晓雪杨蓉吴琼谢可辉付宏征更多>>
相关机构:中国科学院北京大学扬州大学中国医学科学院中国协和医科大学更多>>
相关期刊:《Progress in Natural Science:Materials International》《Petroleum Science》《Molecular Plant》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金国家教育部博士点基金更多>>
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Ent-pimarane and ent-kaurane diterpenoids from Siegesbeckia pubescens and their anti-endothelial damage effect in diabetic retinopathy
《Chinese Journal of Natural Medicines》2025年第2期234-244,共11页Mengjia Liu Tingting Luo Rongxian Li Wenying Yin Fengying Yang Di Ge Na Liu 
supported by the National Natural Science Foundation of China (No.82073728);the Natural Science Foundation of Shandong Province (No.ZR2021MH357)。
Diabetic retinopathy,a prevalent and vision-threatening microvascular complication of diabetes mellitus,is the leading cause of blindness among middle-aged and elderly individuals.Natural diterpenoids isolated from Si...
关键词:Siegesbeckia pubescens Natural diterpenoid Diabetic retinopathy Oxidative stress Inflammatory response 
Discovery of antitumor diterpenoids from Casearia graveolens targeting VEGFR-2 to inhibit angiogenesis
《Chinese Journal of Natural Medicines》2024年第9期842-853,共12页WANG Sibei LIU Yuhui LIANG Yue XI Yaru ZHAI Yupeng LEE Dongho XU Jing GUO Yuanqiang 
supported by the National Natural Science Foundation of China(No.22077067);the Project of State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University[No.QJJ(2022)422];the 111 Project(No.B20016)。
Eight novel clerodane diterpenoids(1-8)were isolated from the twigs of Casearia graveolens.Their structures were elucidated through comprehensive nuclear magnetic resonance(NMR),high-resolution electrospray ionization...
关键词:Clerodane diterpenoids Casearia graveolens Surface plasmon resonance Vascular endothelial growth factor receptor 2 Antitumor activity ZEBRAFISH 
New pimarane diterpenoids with antibacterial activity from fungus Arthrinium sp.ZS03
《Chinese Journal of Natural Medicines》2024年第4期356-364,共9页ZHAO Songfeng JING Ziwei 
supported by the National Natural Science Foundation of China(No.82003956);the Henan Young Elite Scientists Sponsorship Program(No.2023HYTP032)。
A comprehensive chemical study of the endophytic fungus Arthrinium sp. ZS03, associated with Acorus tatarinowii Schott, yielded eleven pimarane diterpenoids (compounds 1–11), including seven novel compounds designate...
关键词:Arthrinium sp.ZS03 Pimarane diterpenoids Structural elucidation Antibacterial activity 
Abietane diterpenoids and iridoids from Caryopteris mongolica
《Chinese Journal of Natural Medicines》2023年第12期927-937,共11页ZHANG Shanshan MAO Xudong XU Hongtao WEI Xiaohui CHOU Guixin 
This work was supported by the National Nature Science Foundation of China(No.21672152).
Six new abietane diterpenoids(1−6)and five undescribed iridoids(7−11)have been isolated from the aerial parts of Caryopteris mongolica.The intricate structural characterization of these compounds was meticulously unde...
关键词:Caryopteris mongolica Abietane diterpenoids Spectroscopic analysis CYTOTOXICITY 
Antimalarial and neuroprotective ent-abietane diterpenoids from the aerial parts of Phlogacanthus curviflorus
《Chinese Journal of Natural Medicines》2023年第8期619-630,共12页LI Jia MENG Xiao YIN Chengyue ZHANG Lixia LIN Bin LIU Peng ZHU Lingjuan WANG Haifeng LIU Hongwei ZHANG Xue YAO Xinsheng 
Six new ent-abietane diterpenoids,abientaphlogatones A−F(1−6),along with two undescribed ent-abietane diterpenoid glucosides,abientaphlogasides A−B(7−8)and four known analogs were isolated from the aerial parts of Phl...
关键词:Phlogacanthus curviflorus Acathaceae ent-Abietane diterpenoids Antimalarial activity Neuroprotective effect 
New di-spirocyclic labdane diterpenoids from the aerial parts of Leonurus japonicus
《Chinese Journal of Natural Medicines》2023年第7期551-560,共10页CAO Xinxin WANG Xinxin ZHANG Yu XU Defeng SONG Xiuqing YU Jinhai BAO Jie ZHANG Junsheng ZHANG Hua 
supported by the Natural Science Foundation of Shandong Province(No.JQ201721);the Young Taishan Scholars Program(No.tsqn20161037).
Phytochemical investigation on the ethanol extract of a well-known medicinal herb Leonurus japonicus,led to the separation of 18 labdane type diterpenoids(1-18).Through comprehensive spectroscopic analyses and quantum...
关键词:Leonurus japonicus LABDANE DITERPENOID Neuroprotective activity 
Biosynthesis and regulation of diterpenoids in medicinal plants被引量:3
《Chinese Journal of Natural Medicines》2022年第10期761-772,共12页REN Junze WU Yu HU Zhanpin CHEN Ruibing ZHANG Lei 
supported by the National Natural Science Foundation of China(Nos.82225047,32000231,31970316 and 32170274);Shanghai Sail Program(No.19YF1459300).
Plant diterpenoids are widely distributed and abundant natural products with diverse structures and functions in nature,which have been commonly used in pharmaceutical,agricultural and industrial production.In recent ...
关键词:DITERPENOID Pharmaceutical value BIOSYNTHESIS REGULATION Medicinal plant 
A review:biosynthesis of plant-derived labdane-related diterpenoids被引量:3
《Chinese Journal of Natural Medicines》2021年第9期666-674,共9页GAO Ke ZHA Wen-Long ZHU Jian-Xun ZHENG Cheng ZI Jia-Chen 
Plant-derived labdane-related diterpenoids(LRDs)represent a large group of terpenoids.LRDs possess either a labdane-type bicyclic core structure or more complex ring systems derived from labdane-type skeletons,such as...
关键词:BIOSYNTHESIS Cytochrome P450 enzyme Diterpene synthase Labdane-related diterpenoids 
3,4-seco-Isopimarane and 3,4-seco-pimarane diterpenoids from Callicarpa nudiflora被引量:3
《Chinese Journal of Natural Medicines》2021年第8期632-640,共9页HUANG Hang TANG Chun-Ping KE Chang-Qiang SHU Ren-Geng YE Yang 
supported from the China National Key R&D Program(Nos.2017YFE0195100 and 2018YFC.707000);the National Natural Science Foundation of China(Nos.21920102003 and 81903485)。
A phytochemical investigation was carried out on the extract of a medicinal plant Callicarpa nudiflora,resulting in the characterization of five new 3,4-seco-isopimarane(1-5)and one new 3,4-seco-pimarane diterpenoid(6...
关键词:Callicarpa nudiflora 3 4-seco-Isopimarane 3 4-seco-Pimarane TDDFT-ECD DFT calculation 
New lobane-type diterpenoids from the Xisha soft coral Sinularia polydactyla被引量:1
《Chinese Journal of Natural Medicines》2020年第11期839-843,共5页YE Fei CHEN Zi-Hui GU Yu-Cheng GUO Yue-Wei LI Xu-Wen 
supported by the National Key Research and Development Program of China (No. 2018YFC-0310903);the Natural Science Foundation of China (Nos. 81991521;21672230;and 81520108028);the NSFC/CNRS Joint Project (No.81811530284);the SKLDR/SIMM Project (No. SIMM1903ZZ-04);Shanghai Rising-Star Program (No. 20QA1411100);SA-SIBS Scholarship Program;Syngenta-SIMM-Ph D Studentship Project。
Lobane-type diterpenoids are not frequently discovered from marine soft corals. In this paper, three new lobane type diterpenes, 13-methoxyloba-8,10,15(16),17(18)-tetraene(1), 8,10,13(15)Z,16 E-lobatetraene(2) and 19-...
关键词:Soft coral Sinularia polydactyla Lobane DITERPENES 
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