云南高校图书馆联盟文献共享服务平台- GALECTIN

GALECTIN: 作品数：52被引量：124H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李祥瑞黄慧聪张晓龙郑爱仙廖乃顺更多>>; 相关机构：南京农业大学北京协和医学院武汉大学中国医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中央高校基本科研业务费专项资金江苏高校优势学科建设工程资助项目更多>>

Galectin 3-binding protein(LGALS3BP)depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1(TGF-β1)availability and inhibits hepatocarcinogenesis: 《Cancer Communications》2024年第10期1106-1129,共24页Dae-Hwan Kim Minjeong Sung Myong-Suk Park Eun-Gene Sun Sumin Yoon Kyung Hyun Yoo Kamalakannan Radhakrishnan Sung Yun Jung Woo-Kyun Bae Sang-Hee Cho Ik-Joo Chung; Bio&Medical Technology Development Program of the National Research Foundation,Grant/Award Numbers:NRF-2020M3A9G3080281,NRF-2020R1A5A2031185;Korean Government。; Background:Increased Galectin 3-binding protein(LGALS3BP)serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma(HCC).Considering the crucial role of transforming gro...; 关键词：F-ACTIN FAK hepatic carcinogenesis IntegrinαV Interferonα JUNB LGALS3BP metabolic dysfuntion-associated steatohepatitis tensile force TGF-Β1

血清Tim-3、Galectin-9水平与老年COPD患者急性加重、肺功能下降的关系被引量：1: 《中国老年学杂志》2024年第17期4128-4131,共4页汪艳霞朱益鹏; 目的探讨血清T细胞免疫球蛋白黏蛋白分子(Tim)-3、半乳糖凝集素(Galectin)-9水平与老年慢性阻塞性肺疾病(COPD)患者急性加重、肺功能下降的关系。方法将94例老年COPD稳定期患者作为稳定期组,108例老年COPD急性加重期患者作为急性加重期...; 关键词：T细胞免疫球蛋白黏蛋白分子(Tim)-3 半乳糖疑集素(Galectin)-9 慢性阻塞性肺疾病急性加重期肺功能

Emerging role of galectin 3 in neuroinflammation and neurodegeneration被引量：2: 《Neural Regeneration Research》2024年第9期2004-2009,共6页Brian M.Lozinski Khanh Ta Yifei Dong; Neuroinflammation and neurodegeneration are key processes that mediate the development and progression of neurological diseases.However,the mechanisms modulating these processes in different diseases remain incomplete...; 关键词：Alzheimer’s disease Galectin 3 MICROGLIA multiple sclerosis NEURODEGENERATION NEUROINFLAMMATION Parkinson’s disease THERAPEUTICS

Galectin 2 regulates JAK/STAT3 signaling activity to modulate oral squamous cell carcinoma proliferation and migration in vitro: 《BIOCELL》2024年第5期793-801,共9页XINRU FENG LI XIAO; supported by grants from Key R&D Project of Science and Technology Foundation of Sichuan Province(2022YFS0290).; Background:Galectin 2(LGALS2)is a protein previously reported to serve as a mediator of disease progression in a range of cancers.The function of LGALS2 in oral squamous cell carcinoma(OSCC),however,has yet to be expl...; 关键词：LGALS2 Oral squamous cell carcinoma(OSCC) Janus Kinase 2/Signal Transducer and Activator of Transcription 3(JAK2-STAT3) PROGRESSION

花鲈半乳糖凝集素基因家族的鉴定及在不同环境因子胁迫下表达响应: 《中国海洋大学学报（自然科学版）》2024年第1期35-47,共13页郑圆温海深李吉方方秀王灵钰张冲陶泽鑫张永航李昀; 国家重点研究发展计划项目(2020YFD0900204);国家现代农业产业技术体系项目(CARS-47)资助。; 为探究在花鲈(Lateolabrax maculatus)响应环境因子胁迫中半乳糖凝集素(Galectins)发挥的作用,本研究通过全基因组水平鉴定获得了花鲈的14个Galectin基因(LGALS1、LGALS2a、LGALS2b、LGALS3a、LGALS3ba、LGALS3bb、LGALS4、LGALS8a、LGA...; 关键词：花鲈 Galectin基因家族表达分析胁迫响应

Targeting stroma and tumor,silencing galectin 1 treats orthotopic mouse hepatocellular carcinoma被引量：3: 《Acta Pharmaceutica Sinica B》2024年第1期292-303,共12页Tahereh Setayesh Ying Hu Farzam Vaziri Xin Chen Jinping Lai Dongguang Wei Yu-Jui Yvonne Wan; The authors thank the Genomics Shared Resource(GSR)core facility at the University of California,Davis Health,Dr.Clifford G Tepper,Stephanie Liu,Ryan Davis,for helping in performing spatial RNA sequencing,and William Amato for his assistance in the quantification of immunohistochemistry slides.This manuscript is supported by grants funded by the USA National Institutes of Health(NIH)T32 CA108459e15,R01CA222490,R50CA243787.BioRender was used to draw mice figures in schematic experimental design.; This study examines inhibiting galectin 1(Gal1)as a treatment option for hepatocellular carcinoma(HCC).Gal1 has immunosuppressive and cancer-promoting roles.Our data showed that Gal1 was highly expressed in human and ...; 关键词：Liver Hepatocellular carcinoma Carbohydrate-binding lectin Galectin 1 Extracellular matrix Translation Spatial transcriptomics Tumor-margin

血清Galectin⁃9、CXCL10对急性心肌梗死患者急诊PCI术后慢血流现象的预测效能被引量：3: 《分子诊断与治疗杂志》2023年第9期1515-1519,共5页顾冬冬程键孔菲菲吴海艳刘玉飞; 安徽省重点研究与开发计划项目(1704f0804023)。; 目的探讨血清半乳糖凝集素⁃9(galectin⁃9)、血清CXC趋化因子配体10(CXCL10)对急性心肌梗死(AMI)患者急诊经皮冠状动脉介入治疗(PCI)术后冠状动脉慢血流(CSF)现象的评估价值。方法选取2019年12月至2022年12月合肥京东方医院收治的102例...; 关键词：半乳糖凝集素⁃9 CXC趋化因子配体10 急性心肌梗死冠状动脉慢血流

HSV-2感染与急性缺血性脑卒中患者Galectin 9/Tim-3信号通路及预后的关系被引量：2: 《中华医院感染学杂志》2023年第14期2116-2120,共5页张林林冯涛赵耀王婷闫丽; 河南省医学科技攻关基金资助项目(202003053)。; 目的探讨单纯疱疹病毒2型(HSV-2)感染与急性缺血性脑卒中(AIS)患者对配体半乳凝素-9(Galectin 9)/T细胞免疫球蛋白黏蛋白分子-3(Tim-3)信号通路及预后的关系。方法回顾性收集2018年1月-2021年1月南阳医学高等专科学校第一附属医院75例AI...; 关键词：急性缺血性脑卒中单纯疱疹病毒2型配体半乳凝素-9 T细胞免疫球蛋白黏蛋白分子-3 预后

新生儿坏死性小肠结肠炎患儿血清Galectin 3和IGF-1表达及临床意义被引量：4: 《现代检验医学杂志》2023年第2期166-170,共5页肖二明金晓艳杨常栓; 河北省重点科技研究计划(20180052)。; 目的研究坏死性小肠结肠炎(necrotizing enterocolitis,NEC)患儿血清半乳糖凝集素3(Galectin-3,Gal-3)和胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)的表达及临床意义。方法选取2019年1月~2021年2月廊坊市妇幼保健院诊治...; 关键词：新生儿坏死性小肠结肠炎半乳糖凝集素3 胰岛素样生长因子-1

Relationship between Circulating Plasma Galectin-3 Levels and T-Cell Activation during Cervical Cancer Chemotherapy: 《Open Journal of Immunology》2023年第1期14-31,共18页Folly M. Gaba Maïmouna Diop Doudou G. M. Niang Sidy Ka Doudou Diouf Moussa Ndour Comlan J. G. Montcho Moustapha Mbow Babacar Faye Rokhaya N. Diallo Maguette S. Niang Ahmadou Dem Babacar Mbengue Alioune Dieye; Objective: Despite the existence of several therapeutic strategies, the management of cervical cancer remains challenging. Our region has very little data on the interaction between the immune system and the clinical ...; 关键词：Uterine Cervical Neoplasm CHEMOTHERAPY Galectin 3 T-Lymphocytes Activation

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