ANTI-INFLAMMATORY

作品数：629被引量：1827H指数：19
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相关作者：徐献梅张燕平任荣董金华许丁元更多>>
相关机构：东南大学贵阳中医学院第二附属医院昆明理工大学北里大学更多>>
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Dissolvable microneedle-based wound dressing transdermally and continuously delivers anti-inflammatory and pro-angiogenic exosomes for diabetic wound treatment被引量：2
《Bioactive Materials》2024年第12期32-51,共20页Yanpeng Cao Bei Chen Qixing Liu Yiyang Mao Yusheng He Xiaoren Liu Xin Zhao Yaowu Chen Xiying Li Yabei Li Liang Liu Chengwu Guo Shiyu Liu Fenghua Tan Hongbin Lu Jun Liu Can Chen 
financially supported through grants from the National Natural Science Foundation of China(Grant No.82272497);Hunan Provincial Natural Science Foundation(Grant Nos.2021JJ20093,2022JJ30001,2023JJ40090);the Hunan Provincial Health Commission Scientific Research Projects(Grant No.202204075237).
Due to overactive inflammation and hindered angiogenesis,self-healing of diabetic wounds(DW)remains challenging in the clinic.Platelet-derived exosomes(PLT-Exos),a novel exosome capable of anti-inflammation and pro-an...
关键词：Acellular dermal matrix Diabetic wound EXOSOMES MICRONEEDLE Transdermal delivery 
Intrinsically bioactive multifunctional Poly(citrate-curcumin) for rapid lung injury and MRSA infection therapy
《Bioactive Materials》2024年第11期158-173,共16页Tongtong Leng Long Zhang Junping Ma Xiaoyan Qu Bo Lei 
National Natural Science Foundation of China(grant No.52172288);Young Talent Support Plan of Xi'an Jiaotong University of China(grant No.QY6J003)。
Dysregulated inflammation after trauma or infection could result in the further disease and delayed tissue reconstruction.The conventional anti-inflammatory drug treatment suffers to the poor bioavailability and side ...
关键词：Bioactive materials Bioactive polymers Citrate polymer ANTI-INFLAMMATORY Inflammatory diseases 
Thermo-sensitive Poloxamer based antibacterial anti-inflammatory and photothermal conductive multifunctional hydrogel as injectable,in situ curable and adjustable intraocular lens
《Bioactive Materials》2024年第11期30-45,共16页Chen Qin Fan Fei Youfei Wei Yuemei Han Di Hu Quankui Lin 
Zhejiang Provincial Natural Science Foundation[LR23H180001];Key Scientific and Technological Innovation Projects in Wenzhou[ZY2021002].
Cataract patients look forwards to fewer postoperative complications and higher vision quality after surgery.However,the current intraocular lens(IOL)implanted after cataract surgery neither can adjust focal length in...
关键词：Adjustable IOL Injectable hydrogel ANTIBACTERIAL ANTI-INFLAMMATORY 
Magnesium implants with alternating magnetic field-enhanced hydrogen release and proton depletion for anti-infection treatment and tissue repair
《Bioactive Materials》2024年第8期374-383,共10页Nailin Yang Xiaoyuan Yang Shuning Cheng Xiang Gao Shumin Sun Xuan Huang Jun Ge Zhihui Han Cheng Huang Yuanjie Wang Chong Cheng Liang Cheng 
supported by the National Key Research and Development Program of China(2022YFB3804600,2021YFF0701800);the National Natural Science Foundation of China(U20A20254,52072253);the Science and Technology Development Fund,Macao SAR(0118/2023/RIA2);Collaborative Innovation Center of Suzhou Nano Science and Technology,Suzhou Key Laboratory of Nanotechnology and Biomedicine,the Jiangsu Natural Science Fund for Distinguished Young Scholars(BK20211544);the 111 Project,Joint International Research Laboratory of Carbon-Based Functional Materials and Devices,Medical Research Project of Jiangsu Province(ZD2022024);New Cornerstone Science Foundation through the XPLORER PRIZE,and Key Laboratory of Structural Deformities in Children of Suzhou(SZS2022018);N.Y.was supported by the Macao Young Scholars Program and the Jiangsu Funding Program for Excellent Postdoctoral Talent.
Implant-related osteomyelitis is a formidable hurdle in the clinical setting and is characterized by inflammation,infection,and consequential bone destruction.Therefore,effective reactive oxygen species(ROS)scavenging...
关键词：Magnesium implants Bacterial infection Alternating magnetic field Gas therapy Proton consumption ANTI-INFLAMMATORY 
Niobium carbide MXenzyme-Driven comprehensive cholesterol regulation for photoacoustic image-guided and anti-inflammatory photothermal ablation in atherosclerosis
《Bioactive Materials》2024年第6期565-579,共15页Wenqi Pan Jingyun Cheng Xinyue Cao Yi Zheng Zhenyu Yang Wei Feng Yu Chen Rong Wu 
the Shanghai General Hospital Clinical Center Laboratory Animal Welfare&Ethics Committee(License number:2023AW017).
Foam cells play a pivotal role in the progression of atherosclerosis progression by triggering inflammation within arterial walls.They release inflammatory molecules that attract additional immune cells,leading to fur...
关键词：ATHEROSCLEROSIS MXenzyme Lipid regulation ANTI-INFLAMMATION THERANOSTICS 
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds被引量：9
《Bioactive Materials》2024年第4期298-310,共13页Shunlai Shang Kaiting Zhuang Jianwen Chen Ming Zhang Shimin Jiang Wenge Li 
supported by National High Level Hospital Clinical Research Funding,(2023-NHLHCRF-YS-01);Elite Medical Professionals Project of China-Japan Friendship Hospital(ZRJY2023-GG06);the China Postdoctoral Science Foundation(Certificate Number:2023M733986 and 2023T160741);Cross-sectional project of China-Japan Friendship Hospital(Certificate Number:2023-HX-JC-10);International Association of Chinese Nephrologists Research Grant(No.IACNRG-01);Beijing Hospitals Authority Clinical medicine Development of special funding support(Certificate Number:ZLRK202308).
Mesenchymal stem cell derived exosomes(MSC-Exos)demonstrate beneficial effects on wound healing via anti-inflammatory and angiogenic properties.Chitosan(CS)exhibits excellent biocompatibility and accelerates cellular ...
关键词：EXOSOMES Bioactive glass Diabetic wound ANTI-INFLAMMATORY Titanium dioxide 
Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions被引量：4
《Bioactive Materials》2024年第1期298-311,共14页Nandin Mandakhbayar YunSeong Ji Ahmed El-Fiqi Kapil DPatel Dong Suk Yoon Khandmaa Dashnyam Oyunchimeg Bayaraa Gangshi Jin Khaliunsarnai Tsogtbaatar Tae-Hyun Kim Jung-Hwan Lee Hae-Won Kim 
supported by the National Research Foundation of Korea(2021R1A5A2022318,2018K1A4A3A01064257,2019R1A6A1 A11034536,RS-2023-00220408,2022K1A3A1A08085419,2021R1I1 A1A01049104).
Regeneration of pathological wounds,such as diabetic ulcers,poses a significant challenge in clinical settings,despite the widespread use of drugs.To overcome clinical side effects and complications,drug-free therapeu...
关键词：Diabetic wound Nanozyme ANTI-INFLAMMATION Angiogenesis Therapeutic materials 
Continuously released Zn^(2+)in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties被引量：3
《Bioactive Materials》2023年第6期361-375,共15页Chunxu Li Fengbo Sun Jingjing Tian Jiahao Li Haidan Sun Yong Zhang Shigong Guo Yuanhua Lin Xiaodan Sun Yu Zhao 
supported by Tsinghua University-Peking Union Medical College Hospital Initiative Scientific Research Program(20191080871);the National Natural Science Foundation of China(82272464,82002314).
Long-term nonunion of bone defects has always been a major problem in orthopedic treatment.Artificial bone graft materials such as Poly(lactic-co-glycolic acid)/β-tricalcium phosphate(PLGA/β-TCP)scaffolds are expect...
关键词：3D printing Zinc submicron particles OSTEOINDUCTIVITY ANTI-INFLAMMATORY Bone defect repair 
Protein-spatiotemporal partition releasing gradient porous scaffolds and anti-inflammatory and antioxidant regulation remodel tissue engineered anisotropic meniscus
《Bioactive Materials》2023年第2期194-207,共14页Bingbing Xu Jing Ye Bao-Shi Fan Xinjie Wang Ji-Ying Zhang Shitang Song Yifan Song Wen-Bo Jiang Xing Wang Jia-Kuo Yu 
the National Natural Science Foundation of China(NSFC,82002298,51920105006,51973226);the China Postdoctoral Science Foundation(2020M670066);the National Key Research and Development Program of China(2016YFC1100704);the Youth Innovation Promotion Association CAS(2019031).
Meniscus is a wedge-shaped fibrocartilaginous tissue,playing important roles in maintaining joint stability and function.Meniscus injuries are difficult to heal and frequently progress into structural breakdown,which ...
关键词：Tissue engineering meniscus Gradient porous scaffolds Spatiotemporal partition release Ac2-26 peptide Anti-inflammatory and anti-oxidant regulation 
An anti-inflammatory and neuroprotective biomimetic nanoplatform for repairing spinal cord injury被引量：6
《Bioactive Materials》2022年第12期569-582,共14页Xiang Gao Zhihui Han Cheng Huang Huali Lei Guangqiang Li Lin Chen Dandan Feng Zijie Zhou Qin Shi Liang Cheng Xiaozhong Zhou 
the National Natural Science Foundation of China(U20A20254,52072253,81873995,81171712);Social development program of Jiangsu province(BE2019662);Gusu medical talents program of Suzhou(20015);Health commission of Jiangsu province(H2017066);the Natural Science Foundation of Jiangsu Province(BK20151213,SBK2019040088);Collaborative Innovation Center of Suzhou Nano Science and Technology,and a Project Funded by the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.Jiangsu Province Six Talent Peaks Project(No.SWYY-110);Key laboratory of spinal cord injury repair of Suzhou(SZS201807).
Spinal cord regeneration after a spinal cord injury (SCI) remains a difficult challenge due to the complicated inflammatory microenvironment and neuronal damage at the injury sites. In this study, retinoic acid (RA) a...
关键词：Biomimetic nanomaterials ROS scavenging ANTI-INFLAMMATORY Spinal cord injury Neuro-protective 
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