supported by the National Natural Science Foundation of China(31802142);the Doctoral Start-up Fund of the Southwest University(SWU120019);the F undamental Research Funds for the Central Universi-ties(XDJK2019C089);the project funded by the China Postdoctoral Science Foundation(2019T120801 and 2017M620408).
Insect hemocytes play important biological roles at developmental stages,metamorphosis,and innate immunity.As one of the most abundant cell types,plasmatocytes can participate in various innate immune responses,especi...
supported by the grants of the National Natural Science Foundation of China(31970475 and 32170832 to YS,31970506 and 32170541 to LZ);the Fundamen-tal Research Funds for Central Universities,China(202012004 to LZ).
Macrophages are well known for their phagocytic functions in innate immunity across species.In mammals,they rapidly consume a large amount of energy by shifting their metabolism from mitochondrial oxidative phosphoryl...
We wish to thank Prof.Herwig Gutzeit for valuable discussions and providing antibody stocks.We would like to express our gratitude to Dr.Alexander Froschauer and Prof.Klaus Reinhardt who hosted the work in their laboratories,to Prof.Thorsten Mascher and Prof.Christian Dahmann for allowing us to use their laboratory equipment,and Dr.Diana Wolf who provided bacteria strains.We thank Dr.Uwe Töpfer for valuable discussions and assistance in microscopy,Dennis Höfling for Hermetia breeding,and Katharina Starke,Yvonne Henker and Christin Froschauer for assistance in the laboratory.We thank the two anonymous reviewers for their helpful comments that improved the quality of the manuscript significantly.
With the growing importance of the black soldier fly(Hermetia illucens)for both sustainable food production and waste management as well as for science,a great demand of understanding its immune system arises.Here,we ...
the National Key R&D Program of China(2017YFD200400);Guangdong Basic and Applied Basic Research Foundation(2020A 1515010455);the National Natural Science Foundation of China(31272091);the Key Project of Chinese National Programs for Fundamental Research and Development(973 programs,2013CB 127603);the International Foundation for Scicncc(C3680-2).
Granulocytes and plasmatocytes play important roles in clearing foreign objects in insects,but it is difficult to distinguish between them in immune reactions.Based on the hemocyte cell line SYSU-OfHe-C established at...
supported by grants from NIH to Z.H.(R01-HL134940,R01-DK098410)。
Drosophila has been extensively used to model the human blood-immune system,as both systems share many developmental and immune response mechanisms.However,while many human blood cell types have been identified,only t...
Innate immunity is essential for the wellbeing of vertebrates and invertebrates. Key components of this defense system include pattern recognition receptors that bind to infectious agents, extra-and intra-cellular pro...