NUCLEOTIDE-BINDING

作品数:29被引量:49H指数:4
导出分析报告
相关领域:医药卫生更多>>
相关作者:邹正升李保森黄昂孙颖张岚更多>>
相关机构:北京大学东南大学四川大学更多>>
相关期刊:《World Journal of Gastrointestinal Surgery》《World Journal of Hepatology》《Plant Communications》《World Journal of Traditional Chinese Medicine》更多>>
相关基金:国家自然科学基金福建省自然科学基金天津市自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Genetic and environmental factors influencing Crohn’s disease
《World Journal of Gastrointestinal Surgery》2025年第3期1-5,共5页Ye-Hui Fan Ming-Wei Wang Yu-Ning Gao Wen-Mao Li Yan Jiao 
This editorial discusses Pellegrino and Gravina's essay.Crohn’s disease(CD)is a complex and multifactorial disease that is influenced by a combination of genetic and environmental factors.While genetic factors play a...
关键词:Crohn’s disease PATHOGENESIS Nucleotide-binding oligomerization domain-2 SMOKING Vitamin D 
Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy
《Chinese Journal of Integrative Medicine》2025年第1期19-27,共9页LIU Tian-yi HAO Yu MAO Qin ZHOU Na LIU Meng-hua WU Jun WANG Yi YANG Ming-rui 
Supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202006);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(No.CI2021A00601 and CI2021B017-09)。
Objective: To investigate the inhibitory effect of Tanreqing Injection(TRQ) on the activation of nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3(NLRP3) inflammasome in macrophages inf...
关键词:Tanreqing Injection influenza virus ANTI-INFLAMMATION MITOPHAGY nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 inflammasome Chinese medicine 
Teneligliptin mitigates diabetic cardiomyopathy through inflammasome inhibition:Insights from experimental studies
《World Journal of Diabetes》2024年第12期2370-2375,共6页Chun-Yao Cheng Wen-Rui Hao Ju-Chi Liu Tzu-Hurng Cheng 
This article provides commentary on the article by Zhang et al.In this original research,Zhang et al investigated the therapeutic potential of teneligliptin for diabetic cardiomyopathy(DCM),which was mediated by targe...
关键词:Diabetic cardiomyopathy Teneligliptin Nucleotide-binding oligomerization domain-like receptor 3 inflammasome Inflammasome inhibition 
Effects of Rutaecarpine on Chronic Atrophic Gastritis Through Nucleotide-binding Oligomerization Domain-like Receptors and Inflammasomes
《World Journal of Traditional Chinese Medicine》2024年第3期303-315,共13页Yong He Xin Wang Li-Sheng Chen Lei Chang Ting-Ting He Ao-Zhe Zhang Hao-Tian Li Shi-Zhang Wei Man-Yi Jing Yan-Ling Zhao 
supported by the Major Program of the National Natural Science Foundation of China (No. 82192915);the National Key Research and Development Program (No. 2018YFC1704500)
Objective: Chronic atrophic gastritis(CAG) is a complex and burdensome disease. However, side effects and compliance issues cannot be ignored due to the long treatment cycle. Numerous studies have confirmed the effect...
关键词:Chronic atrophic gastritis infiammasome nucleotide‑binding oligomerization domain‑like receptors PYROPTOSIS RUTAECARPINE 
Weiwei Decoction alleviates gastric intestinal metaplasia through the olfactomedin 4/nucleotide-binding oligomerization domain 1/caudaltype homeobox gene 2 signaling pathway
《World Journal of Gastrointestinal Oncology》2024年第7期3211-3229,共19页Di-Shu Zhou Wei-Jian Zhang Shu-Ya Song Xin-Xin Hong Wei-Qin Yang Juan-Juan Li Jian-Qu Xu Jian-Yuan Kang Tian-Tian Cai Yi-Fei Xu Shao-Ju Guo Hua-Feng Pan Hai-Wen Li 
Supported by National Natural Science Foundation of China,No.82104747 and No.82305133;Basic and Applied Basic Research Foundation of Guangdong Province,China,No.2020A1515110947;General Project of Shenzhen Science and Technology Innovation Commission,No.JCYJ20230807094659030,No.JCYJ20230807094805012,No.JCYJ20210324111602007,and No.JCYJ20220531091815034;the Scientific Research Project of Guangdong Provincial Bureau of Traditional Chinese Medicine,No.20221349.
BACKGROUND Gastric intestinal metaplasia(IM)is a precancerous lesion that is associated with an elevated risk of gastric carcinogenesis.Weiwei Decoction(WWD)is a promising traditional Chinese herbal formula widely emp...
关键词:Gastric intestinal metaplasia Weiwei Decoction Olfactomedin 4 Nucleotide-binding oligomerization domain 1 Caudal-type homeobox gene 2 Gastric cancer 
Wheat zinc finger protein TaZF interacts with both the powdery mildew AvrPm2 protein and the corresponding wheat Pm2a immune receptor
《Plant Communications》2024年第5期25-41,共17页Beatrice Manser Helen Zbinden Gerhard Herren Joel Steger Jonatan Isaksson Stephanie Braunlich Thomas Wicker Beat Keller 
supported by grants from the Swiss National Science Foundation (310030_204165 and 310030B_182833);by funding from the University of Zurich.
Plant defense responses to pathogens are induced after direct or indirect perception of effector proteins or their activity on host proteins.In fungal–plant interactions,relatively little is known about whether,in ad...
关键词:plant immunity plant-fungal interactions pathogen effectors nucleotide-binding leucine-rich repeat immune receptor NLR WHEAT powdery mildew 
Development of a cell-permeable adenine-derived probe for capture of nucleotide-binding proteins in living cells
《Chinese Chemical Letters》2024年第3期243-246,共4页Lihong Liu Rui Chen Gang Xue Chenzhou Hao Weizhi Weng Zhengying Pan 
funding support from the National Natural Science Foundation of China(No.81872749);Shenzhen Science and Technology Innovation Commission(Nos.20200815000631001 and JCYJ20200109120414564);Peking University。
Adenine is an essential building block of genetic material and a range of coenzymes.Chemical probes containing an adenine moiety have been used in kinase profiling studies in cell lysates.Here we report that adenine-d...
关键词:Adenine-derived probe Cell-permeable Lysine residue Protein kinases Nucleotide-binding proteins 
A plasma membrane nucleotide-binding leucinerich repeat receptor mediates the recognition of the Ralstonia pseudosolanacearum effector RipY in Nicotiana benthamiana被引量:1
《Plant Communications》2023年第6期313-328,共16页Boyoung Kim Wenjia Yu Haseong Kim Qian Dong Sera Choi Maxim Prokchorchick Alberto PMacho Kee Hoon Sohn Cécile Segonzac 
supported by the National Research Foundation of Korea(NRF)funded by the Korean Ministry of Education(Global PhD Fellowship Program Project 500–20190213);by the Ministry of Sciences and ICT(Projects 2018R1A5A1023599,2020R1A2C1101419).
Bacterial wilt disease caused by several Ralstonia species is one of the most destructive diseases in Solanaceae crops.Only a few functional resistance genes against bacterial wilt have been cloned to date.Here,we sho...
关键词:typeⅢsecreted effector plant immune system nucleotide-binding leucine-rich repeat receptor virusinduced gene silencing 
Qingchi San(青赤散)treats ulcerative colitis in mice by inhibiting the nuclear factor-kappa B signaling pathway and Nucleotide-binding oligomerization domain,leucine-rich repeat and pyrin domain-containing 3 inflammasome formation
《Journal of Traditional Chinese Medicine》2023年第1期68-77,共10页ZHOU Zhenghua JI Jianbin WANG Hongxia YAN Lin KANG Hongchang 
Supported by the National Key Research and Development Program(Grant 2018YFC1705403):Clinical Effect Evaluation of Chinese Medicine on Moderately Active Ulcerative Colitis;Natural Science Foundation of Tianjin(Grant18JCYBJC26000):Study on the Mechanism of Qingchi San Treating Ulcerative Colitis By Regulating Gut Microflora;Scientific Research Program of Tianjin Education Commission(Grant 2017KJ155):based onγδT-NLRP3 Inflammasome-Caspase Pathway;Qingchi San Regulates Gut Microflora to Treat UC。
OBJECTIVE:To investigate the efficacy of Qingchi San(青赤散,QCS),a preparation of Traditional Chinese Medicine,on ulcerative colitis(UC)in mice by inhibiting the nuclearfactor-kappa B(NF-κB)signaling pathway and nucl...
关键词:colitis ulcerative NF-kappa B disease activity index NLR family pyrin domain-containing 3 protein INFLAMMASOMES Qingchi San 
Gefapixant,a Novel P2X3 Antagonist,Protects against Post Myocardial Infarction Cardiac Dysfunction and Remodeling Via Suppressing NLRP3 Inflammasome
《Current Medical Science》2023年第1期58-68,共11页Yan-zhao WEI Shuang YANG Wei LI Yan-hong TANG 
supported by the National Natural Science Foundation of China(No.81370282).
Objective The ATP responsive P2 purinergic receptors can be subdivided into metabotropic P2X family and ionotropic P2Y family.Among these,P2X3 is a type of P2X receptor which is specifically expressed on nerves,especi...
关键词:myocardial infarction P2X3 inhibition gefapixant nucleotide-binding and oligomerization domain-like receptors family pyrin-domain-containing 3 INFLAMMASOME sympathetic nerve 
检索报告 对象比较 聚类工具 使用帮助 返回顶部