SCARLESS

作品数：13被引量：38H指数：4
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相关领域：医药卫生更多>>
相关作者：王勇王平谢秋萍燕海潮赵群仔更多>>
相关机构：浙江大学医学院附属第二医院更多>>
相关期刊：《Cancer Communications》《Bioactive Materials》《Military Medical Research》《Burns & Trauma》更多>>
相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Biomaterial‑based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration被引量：1
《Military Medical Research》2025年第1期96-120,共25页Ying-Ying Li Shuai-Fei Ji Xiao-Bing Fu Yu-Feng Jiang Xiao-Yan Sun 
supported in part by the National Nature Science Foundation of China(92268206,81830064);the CAMS Innovation Fund for Medical Sciences(CIFMS,2019-I2M-5-059);the Military Medical Research Projects(145AKJ260015000X,2022-JCJQ-ZB-09600);the Military Key Basic Research of Foundational Strengthening Program(2020-JCJQ-ZD-256-021);the Science Foundation of National Defense Science and Technology for Excellent Young(2022-JCJQ-ZQ-017);the Military Medical Research and Development Projects(AWS17J005,2019-126);the Specific Research Fund of The Innovation Platform for Academicians of Hainan Province(YSPTZX202317).
Scar formation resulting from burns or severe trauma can significantly compromise the structural integrity of skin and lead to permanent loss of skin appendages,ultimately impairing its normal physiological function.A...
关键词：SCARLESS Wound healing Biomaterials Mechanical cues Skin appendages 
Emerging biomedical technologies for scarless wound healing
《Bioactive Materials》2024年第12期449-477,共29页Xinyue Cao Xiangyi Wu Yuanyuan Zhang Xiaoyun Qian Weijian Sun Yuanjin Zhao 
supported by the National Key Research and Development Program of China(2022YFB4700100);the National Natural Science Foundation of China(T2225003,52073060 and 61927805);the Nanjing Medical Science and Technique Development Foundation(ZKX21019);the Clinical Trials from Nanjing Drum Tower Hospital(2022-LCYJ-ZD-01);Guangdong Basic and Applied Basic Research Foundation(2021B1515120054);the Shenzhen Science and Technology Program(JCYJ20210324133214038).
Complete wound healing without scar formation has attracted increasing attention,prompting the development of various strategies to address this challenge.In clinical settings,there is a growing preference for emergin...
关键词：Biomedical technologies Scarless wound healing Nonsurgical therapies Biomaterial Drug delivery 
Nano oxygen chamber by cascade reaction for hypoxia mitigation and reactive oxygen species scavenging in wound healing
《Bioactive Materials》2024年第5期67-81,共15页Xiaoxue Han Leah Ju Chai Saengow Wen Ren Randy Ewoldt Timothy Fan Joseph Irudayaraj 
Hypoxia,excessive reactive oxygen species(ROS),and impaired angiogenesis are prominent obstacles to wound healing following trauma and surgical procedures,often leading to the development of keloids and hypertrophic s...
关键词：HYPOXIA ROS scavenging ANTI-INFLAMMATION Oxygen nanobubble Scarless wound healing 
Multi‑Functional Fibrous Dressings for Burn Injury Treatment with Pain and Swelling Relief and Scarless Wound Healing被引量：2
《Advanced Fiber Materials》2023年第6期1963-1985,共23页Zhengchao Yuan Yue Zhao Muhammad Shafiq Jiahui Song Jing Hou Yuqing Liang Xiao Yu Yujie Chen Fan Yu Mohamed EL‑Newehy Hany EL‑Hamshary Yosry Morsi Shichao Jiang Hui Zheng Xiumei Mo 
Science and Technology Commission of Shanghai Municipality(No.20S31900900,20DZ2254900);Sino German Science Foundation Research Exchange Center(M-0263);Taishan Scholars Program of Shandong Province(tsqn201812141);Shandong Provincial Natural Science Foundation(ZR2021MH004);Academic promotion program of Shandong First Medical University(2019RC016);Researchers Supporting Project Number(RSP2023R65);King Saud University,Riyadh,Saudi Arabia,China Education Association for International Exchange(2022181);Donghua University Postgraduate Innovation and Entrepreneurship Ability Training Program(yjssc2023002);Grant-in-Aid for JSPS Research Fellows(JP21F21353);M.S.is an International Research Fellow of the Japan Society for the Promotion of Science(Postdoctoral Fellowships for Research in Japan(Standard));M.S.is keenly grateful to the Gifu University,Japan for Special Cooperative Research Program and College of Biological Science and Medical Engineering,Donghua University,Shanghai,China for cooperative research.
As one of the most common forms of skin injuries,skin burns are often accompanied by edema pain,suppuration of infection,slow tissue regeneration,and severe scar formation,which significantly delay wound healing as we...
关键词：Burn injury Wound healing Skin regeneration Pain and swelling relief Nanofiber membrane 
Efficient scarless skin regeneration enabled by loading micronized amnion in a bioinspired adhesive wound dressing
《Aggregate》2023年第5期96-111,共16页Huicong Zhang Mingyu Song Changhong Hu Zhiyi Zhang Shuqi Zhang Yan Zhang Yingming Yang Puxu Zhou Liwen Zheng Lan Li Mengjie Mao Yu Shrike Zhang Ping Ji Ximu Zhang 
National Natural Science Foundation of China,Grant/Award Numbers:32070826,31871464;Science and Technology Research Project of Chongqing Education Commission,Grant/Award Number:KJQN202200471;Chongqing Science and Health Joint Medical,Grant/Award Number:2020GDRC017;CQMU Program for Youth Innovation in Future Medicine,Grant/Award Number:W0075;Senior Medical Talents Program of Chongqing;Key Research Cultivating Project of Stomatological Hospital of Chongqing Medical University,Grant/Award Number:PYZD201603;Program for Innovation Team Building at Institutions of Higher Education in Chongqing in 2016,Grant/Award Number:CXTDG201602006;Brigham Research Institute。
Complete skin reconstruction is a hierarchical,physiological assembly process involving healing of the epidermis,dermis,vasculature,nerves,and cutaneous appendages.To date,few works have reported complete skin regener...
关键词：AMNION Andrias davidianus cell delivery cutaneous appendages SCARLESS wound dressing 
Anti-oxidant anti-inflammatory and antibacterial tannin-crosslinked citrate-based mussel-inspired bioadhesives facilitate scarless wound healing被引量：10
《Bioactive Materials》2023年第2期93-110,共18页Keke Wu Meimei Fu Yitao Zhao Ethan Gerhard Yue Li Jian Yang Jinshan Guo 
funded by the National Natural Science Foundation of China(NSFC,Grant No.U21A2099,82102545);the Chinese Postdoctoral Science Foundation(Grant No.2021M701627);the Guangdong Basic and Applied Basic Research Foundation(Grant No.2022A1515011982,2020A1515110062).
The revolutionary role of tissue adhesives in wound closure,tissue sealing,and bleeding control necessitates the development of multifunctional materials capable of effective and scarless healing.In contrast to the us...
关键词：ANTI-OXIDANT Hydrogen bond crosslinking Phased angiogenesis Scarless wound healing Tannic acid 
An NIR photothermal-responsive hybrid hydrogel for enhanced wound healing被引量：10
《Bioactive Materials》2022年第10期162-172,共11页Lin Jin Xiaoqing Guo Di Gao Yan Liu Jiahua Ni Zhiming Zhang Yiqiao Huang Guibin Xu Zhe Yang Xingcai Zhang Xianhan Jiang 
supported by the National Natural Science Foundation of China(U1904176,82072808);Henan science and technology research project(222102520004)and Zhongyuan Thousand Talents Plan Project(L.Jin);Guangzhou Core Medical Disciplines Project(2021-2023);Guangdong foundation for basic and applied research(2019A1515010222);Biomedicine Joint Fund of Zhejiang Province(LWY20H180002);the China Postdoctoral Science Foundation(2019M663742).
Moderately regulating vascularization and immune microenvironment of wound site is necessary to achieve scarless wound healing of the skin.Herein,we have prepared an angiogenesis-promoting and scar-preventing band-aid...
关键词：Angiogenesis promotion NIR response HYDROGEL NANOFIBERS Scarless wound healing 
Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery被引量：3
《Acta Pharmacologica Sinica》2020年第1期119-128,共10页Di Sun Shi-yan Guo Li Yang Ya-ru Wang Xiao-hui Wei Sha Song Yi-wei Yang Yong Gan Zheng-tao Wang 
the National Natural Science Foundation of China(81530096 and 81573588).
Inefficient diabetic ulcer healing and scar formation remain a challenge worldwide,owing to a series of disordered and dynamic biological events that occur during the process of healing.A functional wound dressing that...
关键词：diabetic ulcer ordered recovery scarless wound healing 20(S)-protopanaxadiol nanostructured lipid carrier silicone elastomer 
In pursuit of a flawless aphrodite:paving the way to scarless oncoplastic breast surgery被引量：4
《Cancer Communications》2019年第1期712-717,共6页Liling Zhu Shunrong Li Luyuan Tan Xiaolan Zhang Jiannan Wu Fengxi Su Kai Chen Erwei Song 
This project was partially supported by the Yat-sen Scholarship of Young Scientist program of Sun Yat-sen Memorial Hospital,Sun Yat-sen University(Recipient:Kai Chen);the Grant from Guangdong Science and Technology Department(2017B030314026)
Introduction Breast cancer is the most commonly diagnosed malig-nancy in women worldwide[1,2]and in the twentieth century,mastectomy was the primary surgical treatment for breast cancer patients.Advances in breast-con...
关键词：surgery BREAST SCAR 
Reconstruction of a hybrid nucleoside antibiotic gene cluster based on scarless modification of large DNA fragments被引量：7
《Science China(Life Sciences)》2017年第9期968-979,共12页Jiming Zhuo Binbin Ma Jingjing Xu Weihong Hu Jihui Zhang Huarong Tan Yuqing Tian 
supported by grants from the Ministry of Science and Technology of China(2013CB734001 and 2015CB150600);the National Natural Science Foundation of China(31370097 and 31571281)
Genetic modification of large DNA fragments(gene clusters) is of great importance in synthetic biology and combinatorial biosynthesis as it facilitates rational design and modification of natural products to increase ...
关键词：large DNA fragment PCR targeting Gibson assembly gene cluster hybrid antibiotic 
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