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Hymoins A–C,three unusual polycyclic polyprenylated acylphloroglucinols with lipid-lowering activity from Hypericum monogynum
《Chinese Chemical Letters》2025年第3期411-414,共4页Chunmao Yuan Yanrong Zeng Lei Huang Yu Mou Jun Jin Ping Yi Yanmei Li Xiaojiang Hao 
financially supported by the National Natural Science Foundation of China(Nos.32270413,82060631,82160808,and 82360035);the Science and Technology Department of Guizhou Province(Nos.QKHJC 2020–1Z076,QKHJC-ZK[2023]YB156,QKHJC-ZK[2021]YB569,and QKHPTRC[2020]5008);Excellent Young Talents Plan of Guizhou Medical University(2023,No.106);the 13thbatch of outstanding young scientific and technological talents in Guizhou Province(No.QKHPTRC[2021]5633);Guizhou Science and Technology Innovation Talent Team(No.QKHPTRC–CXTD[2022]007);High-level Innovative Talents in Guizhou Province(Thousand Levels of Talent for Chunmao Yuan in 2018);the project of State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University(Nos.FAMP202102K and QJJ[2023]113)。
Hymoins A–C(1–3),three unusual polycyclic polyprenylated acylphloroglucinols(PPAPs)were isolated from the flowers of Hypericum monogynum.Hymoin A features the first intriguing 6/5/5/5/7 pentacyclic caged PPAP.Hymoin...
关键词：Hypericum monogynum Polycyclic polyprenylated ACYLPHLOROGLUCINOLS Structure elucidation Lipid-lowering activity Mechanistic study 
Niduenes A-F,six functionalized sesterterpenoids with a pentacyclic 5/5/5/5/6 skeleton from endophytic fungus Aspergillus nidulans
《Chinese Chemical Letters》2024年第9期202-205,共4页Aimin Fu Chunmei Chen Qin Li Nanjin Ding Jiaxin Dong Yu Chen Mengsha Wei Weiguang Sun Hucheng Zhu Yonghui Zhang 
financially supported by the National Key Research and Development Program of China(No.2021YFA0910500);the National Natural Science Foundation of China(Nos.U22A20380,82104028,82173706 and 82373755);Innovative Research Groups of the National Natural Science Foundation of China(No.81721005);the Science and Technology Major Project of Hubei Province(No.2021ACA012);the Fundamental Research Funds for the Central Universities,HUST(No.2021JYCXJJ058)。
Niduenes A-F(1-6),six novel sesterterpenoids with unprecedented 5/5/5/5/6 pentacyclic ring skeleton were isolated from endophytic fungus Aspergillus nidulans.Compounds 1 and 2 represent the first examples of aromatic ...
关键词：Aspergillus nidulans Sesterterpenoids Aromatic sesterterpenoids Structure elucidation Single-crystal X-ray diffraction Biosynthetic pathways 
Distachydrimanes A-F,phenylspirodrimane dimers and hybrids with cytotoxic activity from the coral-derived fungus Stachybotrys chartarum
《Chinese Chemical Letters》2022年第10期4587-4594,共8页Shuang Lin Jianzheng Huang Hanxiao Zeng Qingyi Tong Xueke Zhang Beiye Yang Ying Ye Jianping Wang Zhengxi Hu Yonghui Zhang 
financially supported by the National Natural Science Foundation for Distinguished Young Scholars(No.81725021);the Innovative Research Groups of the National Natural Science Foundation of China(No.81721005);the National Natural Science Foundation of China(No.81573316);the Fundamental Research Funds for the Central Universities(Nos.2020kfyXJJS083,2021yjsCXCY094 and 2172019kfyXJJS166);the Tongji-Rongcheng Center for Biomedicine,Huazhong University of Science and Technology(No.0231514141);the Research and Development Program of Hubei Province(No.2020BCA058);the Hubei Provincial Natural Science Foundation of China(No.2019CFB646)。
By integrating one strain-many compounds(OSMAC)and LC-MS-based molecular networking strategies,distachydrimanes A-F(1-6),six novel phenylspirodrimane dimers and hybrids representing two types of unprecedented terpenoi...
关键词：Stachybotrys chartarum Distachydrimanes A-F Structure elucidation Cytotoxic activity Mechanism of action 
Structural landscape on a series of rhein:Berberine cocrystal salt solvates:The formation,dissolution elucidation from experimental and theoretical investigations
《Chinese Chemical Letters》2022年第6期3207-3211,共5页Dezhi Yang Hongjuan Wang Qiwen Liu Penghui Yuan Ting Chen Li Zhang Shiying Yang Zhengzheng Zhou Yang Lu Guanhua Du 
the Drug Innovation Major Project(No.2018ZX09711001-001-015);the CAMS Innovation Fund for Medical Sciences(No.2020-I2M-1-003)。
The specific crystalline form of a compound remarkably affects its physicochemical properties.Therefore,a detailed analysis of the structural features and intermolecular interactions of a multi-component crystal is fe...
关键词：COCRYSTAL RHEIN BERBERINE Theoretical computation Energy decomposition analysis SOLUBILITY 
Anti-inflammatory spirobisnaphthalene natural products from a plant-derived endophytic fungus Edenia gomezpompae被引量：1
《Chinese Chemical Letters》2020年第6期1406-1409,F0002,共5页Yingzi Tan Zhikai Guo Mengyue Zhu Jing Shi Wei Li Ruihua Jiao Renxiang Tan Huiming Ge 
financially supported by MOST(Nos.2018YFA0902000 and 2018YFC1706200);National Natural Science Foundation of China(Nos.81925033,21861142005,81773591,21761142001,81673333 and 21661140001);the Central Public-interest Scientific Institution Basal Research Fund for CATAS-ITBB(Nos.1630052020032,19CXTD-32 and 1630052019011);the Hainan Provincial Basic and Applied Basic Research Fund for High-Level Talents in Natural Science(No.2019RC306)。
Spirobisnaphthalenes comprise a relatively rare family of natural products that are normally isolated from fungi and occasionally from plants.Here we reported the discovery of seven new preussomerintype spirobisnaphth...
关键词：Endophytic fungus Spirobisnaphthalene natural products Preussomerin-type Structure elucidation Anti-inflammatory activity 
Neopeapyran, an unusual furo[2,3b]pyran analogue and turnagainolide C from a soil Streptomyces sp. S2236
《Chinese Chemical Letters》2016年第7期1044-1047,共4页Hao Zhou Ya-Bin Yang Rong-Ting Duan Xue-Qiong Yang Ju-Cheng Zhang Xiao-Guang Xie Li-Xing Zhao Zhong-Tao Ding 
funded by grants from the National Natural Science Foundation of China (Nos. 81360480, 81460536 and 81560571)
Neopeapyran（1）,an unusual furo[2,3b]pyran analogue,together with a new cyclopeptide,turnagainolide C（2）,were isolated from Streptomyces sp.S2236 associated with the rhizosphere soil of Panax notoginseng.The planar...
关键词：Streptomyces sp. Furo[2 3b]pyran analogue CYCLOPEPTIDE Structure elucidation Antimicrobial activity 
Two 2-(quinonylcarboxamino)benzoates from the lateral roots of Aconitum carmichaelii被引量：14
《Chinese Chemical Letters》2015年第6期653-656,共4页Zhi-Bo Jiang Xian-Hua Meng Bing-Ya Jiang Cheng-Gen Zhu Qing-Lan Guo Su-Juan Wang Sheng Lin Jian-Gong Shi 
Financial support from the National Natural Science Foundation of China (Nos.21132009 and 30825044);the Program for Changjiang Scholars and Innovative Research Team in University (No.IRT1007);the National Science and Technology Project of China (Nos.2012ZX09301002-002 and 2011ZX0 9307-002-01)
Two new 2-（quinonylcarboxamino）benzoates, named aconicarmiquinamides A （1） and B （2）, were isolated from an aqueous extract of the lateral roots of Aconitum carmichaelii. Their structures were determined by spec...
关键词：Aconitum carmichaelii Ranunculaceae 2-（Quinonylcarboxamino）benzoates Aconicarmiquinamides A and B Methyl 3 6-his（ diethylamino） benzoqunonylcarboxylateStructure elucidation 
Two new b-hydroxy amino acid-coupled secoiridoids from the flower buds of Lonicera japonica:Isolation,structure elucidation,semisynthesis,and biological activities被引量：29
《Chinese Chemical Letters》2014年第9期1215-1219,共5页Wei-Xia Song Yong-Chun Yang Jian-Gong Shi 
Financial support from the National Natural Science Foundation of China (NNSFC; Nos.20772156 and 30825044);the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT,No.IRT1007);the National Science and Technology Project of China (Nos.2012ZX09301002-002 and 2011ZX0 9307002-01)
Two new β-hydroxy amino acid-coupled secoiridoids, named serinosecologanin （1） and threoninose- cologanin （2）, were isolated from an aqueous extract of the flower buds of Lonicera japonica. Their uncommon structu...
关键词：Lonicera japonicaCaprifoliaceae β-Hydroxy amino acid-coupled secoirridoidIsolationStructure elucidationSemisynthesisBiological activity 
Eucleanal A and B:Two new napthalene derivatives from Euclea divinorum
《Chinese Chemical Letters》2012年第5期576-578,共3页Margaret Mwihaki Ng'ang'a Hidayat Hussain Sumesh Chhabra Caroline Langat-Thoruwa Ahmed AI-Harrasi Karsten Krohn Ivan Robert Green 
Two new naphthalene derivatives named eucleanal A and B（1 and 2） were isolated from Euclea divinorum.The structures of the new compounds were elucidated by detailed spectroscopic analysis such as ~1H,^（13）C NMR,CO...
关键词：Euclea divinorum Hiern EBENACEAE NMR Structure elucidation 
A new coumarin from Wikstroemia indica (L.) C.A.Mey被引量：1
《Chinese Chemical Letters》2009年第5期592-594,共3页Yang Chen Wen Wei Fu Li Xin Sun Qia Wang Wei Qi Hua Yu 
A new coumarin was obtained from the stems and roots of Wikstroemia indica （L.） C. A. Mey. Its structure was elucidated as methyl 3-（2-hydroxy-4-（7-hydroxy-6-methoxy-2-oxo-2H-chromen-3-yloxy） phenyl） propanoate ...
关键词：Wikstroemia indica （L.） C.A. Mey COUMARIN Structure elucidation 
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