supported by the National"Ten-Thousand Talents Program"for Leading Talents of Science and Technology Innovation in China,the National Key R&D Program of China (2018YFC1706203);the National Young Qihuang Scholars Training Program,the National Natural Science Foundation of China (82003888,82073963,81522049,82003889);a Key Scientific and Technological Grant of Zhejiang for Breeding New Agricultural Varieties (2021C02074-3);the"Sannongjiufang"Research Joint Project of Zhejiang Province (2023SNJF029);the Zhejiang Provincial Natural Science Foundation of China (LY20H280008);Research Projects of Zhejiang Chinese Medical University (2021JKZKTS011A,2021JKZDZC06,2020010,and YB20023).
Tropane alkaloids(TAs),which are anticholinergic agents,are an essential class of natural compounds,and there is a growing demand for TAs with anesthetic,analgesic,and spasmolytic effects.Anisodus acutan-gulus(Solanac...
Hyoscyamine, anisodamine and scopolamine are tropane alkaloids present in some Solanaceae species and used in modern medicine. L-Hyoscyamine is hydroxylated to 6β
Supported by University of Lagos Central Research Committee Grant(Grant No:2012/08)
Objective:To isolate and screen Actinoniycetes from Lagos Lagoon soil sediments for production of bioactive metabolites.Methods:Sediment samples were collected from four different locations of Lagos Lagoon and were dr...
funded by the National Science Foundation of China for Distinguished Young Scholars(No.81025023);the National Natural Science Foundation of China(No.81202436)
One unusual dimeric tropane alkalolcl, blshyoscyamme, was ISOlated from the roots o! Amsoaus acutangulus, whose structure including the absolute stereochemistry was unambiguously determined based on extensive 1D NMR a...
Callus cultures of Hyoscyamus niger L. were initiated from leaf segments cultured on Murashige and Skoog (MS) medium supplemented with 0.5 mg/L Benzyl Adenine (BA) and 0, 1, 2 and 3 mg/L Naphthalene acetic acid (...
Supported by Natural Science Foundation of Chongqing~~
[Objective] The aim was to clone H6H gene from Atropa belladonna and construct an efficient plant expression vector.[Method] The coding sequence of H6H(Hyoscyamine 6β-hydroxylase)was cloned from Atropa belladonna w...
Abstract: Over the past decade, the evolving commercial importance of so-called plant secondary metabolites has resulted in a great interest in secondary metabolism and, particularly, in the possibilities to enhance t...
Hyoscyamus niger L., medicinal herbs recorded in the famous ancient Chinese medical book Compendium of Materia Medica, are widely dispersed all over China. Anisodamine and anisodine are newly isolated from these medic...