ANTI-DEPRESSANT

作品数：9被引量：23H指数：4
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Carboxymethylation of the polysaccharide from the fermentation broth of Marasmius androsaceus and its antidepressant mechanisms
《Food Science and Human Wellness》2023年第6期2417-2427,共11页Yu Qiu Yan Su Jia Song Fangming Mou Jia Gou Xiaoqi Geng Xinyue Li Zhiqiang Nie Jianxin Wang Yu Zheng Min Wang 
funded by the Natural Science Foundation of China(32072203);the Tianjin Municipal Education Commission(TD13-5013);the Open Project of State Key Laboratory of Food Nutrition and Safety,Tianjin University of Science&Technology(SKLFNS-KF-202102);Natural Science Foundation of Shanxi(201901D211130);Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(2017105);Tianjin synthetic biotechnology innovation capacity improvement project(TSBICIP-KJGG-016);Tianjin Science and Technology Plan Project(21ZYJDJC00030).
To investigate the structure-activity relationship of polysaccharide and obtain a better antidepressant polysaccharide,the antidepressant-like activity of a carboxymethyl polysaccharide(C-MEPS2)subjected to submerged ...
关键词：Carboxymethyl polysaccharide ANTI-DEPRESSANT CATECHOLAMINE 
Mechanisms of repetitive transcranial magnetic stimulation for antidepression: Evidence from preclinical studies被引量：5
《World Journal of Psychiatry》2020年第10期223-233,共11页Di Luan Ming-Ge Zhao Ya-Chen Shi Ling Li Yu-Jia Cao Hai-Xia Feng Zhi-Jun Zhang 
National Key R and D Program of China,No.2016YFC1306700;The Key Projects of National Natural Science Foundation of China,No.81830040;Science and Technology Program of Guangdong,China,No.2018B030334001;Program of Excellent Talents in Medical Science of Jiangsu Province,China,No.JCRCA2016006.
This review summarizes the anti-depressant mechanisms of repetitive transcranial magnetic stimulation in preclinical studies,including anti-inflammatory effects mediated by activation of nuclear factor-E2-related fact...
关键词：Repetitive transcranial magnetic stimulation Anti-depressant mechanisms Nuclear factor-e2-related factor 2 Endocannabinoid system Monoamine oxidase Hypothalamic-pituitary-adrenocortical axis Brain derived neurotrophic factor 
Recent Advances in Ketamine Research: An Update
《Open Journal of Anesthesiology》2020年第3期89-100,共12页Thapa Yuba Raj Ren Quan 
Ketamine is a sedative N-methyl-D-aspartate receptor antagonist, considered as a dissociative anesthetic medication. Ketamine inhibits the voltage-gated Na+ & K+ channels and serotonin and dopamine re-uptake and affec...
关键词：KETAMINE Dissociative ANESTHESIA SEDATIVE PAIN Management ANTI-DEPRESSANT Agent PEDIATRICS ANESTHESIA 
Anti-depressant effects of Jieyu Anshen granule in chronic unpredictable mild stress-treated rats after ischemic stroke
《中国药理学与毒理学杂志》2018年第4期266-267,共2页Yuan DU Yan-qin SONG Lei-ming ZHANG Feng-hua FU 
supported by National Natural Science Foundation of China(8157369)
OBJECTIVE To explore the effects and underlying mechanism of Jieyu Anshen granule(JY) in chronic unpredictable mild stress(CUMS)-treated rats after ischemic stroke.METHODS A rat model of post-stroke depression(PSD) wa...
关键词：郁安神颗粒 脑卒中 治疗方法 临床分析 
Surface modification of PGP for a neutrophil–nanoparticle co-vehicle to enhance the anti-depressant effect of baicalein被引量：4
《Acta Pharmaceutica Sinica B》2018年第1期64-73,共10页Baoyu Chen Man Luo Jianming Liang Chun Zhang Caifang Gao Jue Wang Jianxin Wang Yongji Li Desheng Xu Lina Liu Ning Zhang Huijun Chen Jing Qin 
financial support from the National Natural Science Foundation of China (81673372, 81690263, 81361140344 and 81773911);the National Basic Research Program of China (2013CB 932502);the Opening Project of Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education (Sichuan University, Chengdu, China);the Development Project of Shanghai Peak Disciplines–Integrated Medicine (No. 20150407);the Open Project Program of Key Lab of Smart Drug Delivery (Fudan University, Shanghai, China), Ministry of Education, China
Exploiting cells as vehicles combined with nanoparticles combined with therapy has attracted increasing attention in the world recently. Red blood cells, leukocytes and stem cells have been used for tumor immunotherap...
关键词：PGP peptide NEUTROPHILS Dual-brain targeting delivery Solid lipid nanoparticle Depression BAICALEIN Olfactory bulbectomy rats 
mTOR pathway involved in the fast-onset of anti-depressant effect of YL-0919
《中国药理学通报》2015年第B11期81-81,共1页
Aim YL-0919 is permitted by SFDA for clinical trial recently as a new drug for depression. Whether YL-0919 is a fast-onset antidepressant and the possible mechanism related to roTOR pathway will be investigated. Metho...
关键词：YL-0919 fast-onset ANTIDEPRESSANT ROTOR 
Effective treatment of depression improves post-myocardial infarction survival被引量：8
《World Journal of Cardiology》2015年第4期215-223,共9页Soudabeh Khojasteh Banankhah Erika Friedmann Sue Thomas 
AIM: To examine the contribution of treatment resistant depression(TRD) to mortality in depressed postmyocardial infarction(MI) patients independent of biological and social predictors.METHODS: This secondary analysis...
关键词：DEPRESSION TREATMENT Post-myocardial INFARCTION Mortality ANTI-DEPRESSANT Cognitive behavioral therapy 
SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity被引量：2
《Acta Pharmacologica Sinica》2013年第9期1149-1155,共7页Xing Fang Lin Guo Jia Jia Guo-zhang Jin Bin Zhao Yong-yong Zheng Jian-qi Li Ao Zhang Xue-chu Zhen 
This work was financially supported by grants obtained from the National Natural Science Foundation of China （81130023, 81100918, and 81271214）; National Basic Research Plan （973） of the Ministry of Science and Technology of China （2009CB522000 and 2011CB5C4403）; We also appreciate the support provided by the Priority Academic Program Development of Jiangsu Higher Education Institutes （PAPD） and a grant obtained from the Jiangsu Science and Technology Commission （BY2011131）.
Aim： SKF83959 （3-methyl-6-chloro-7,8-hydroxy-1-（3-methylphenyl）-2,3,4,5-tetrahydro-1H-3-benzazepine） is an atypical dopamine receptor-1 （D1 receptor） agonist, which exhibits many D1 receptor-independent effects...
关键词：SKF83959 monoamine transporter SEROTONIN NOREPINEPHRINE DOPAMINE DEPRESSION DOV21947 
Effects of Yulangsan polysaccharide on monoamine neurotransmitters, adenylate cyclase activity and brain-derived neurotrophic factor expression in a mouse model of depression induced by unpredictable chronic mild stress被引量：4
《Neural Regeneration Research》2012年第3期191-196,共6页Shuang Liang Renbin Huang Xing Lin Jianchun Huang ZhongshiHuang Huagang Liu 
supported by the Scientific Research and Technology Development Program of Guangxi Zhuang Autonomous Region, No. 0630002-2A;the National Natural Science Foundation of China, No. 30960504
The present study established a mouse model of depression induced by unpredictable chronic mild stress. The model mice were treated with Yulangsan polysaccharide （YLSPS; 150, 300 and 600 mg/kg） for 21 days, and comp...
关键词：Yulangsan polysaccharide ANTI-DEPRESSANT chronic stress monoamine neurotransmitter adenylate cyclase brain-derived neurotrophic factor Chinese medicine neural regeneration 
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