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作品数：242被引量：634H指数：13
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相关机构：华中科技大学第二军医大学北京大学第一医院贵州省人民医院更多>>
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Ursolic acid inhibiting excessive reticulophagic flux contributes to alleviate ochratoxin A-induced endoplasmic reticulum stress-and mitochondrial-mediated apoptosis
《Food Science and Human Wellness》2025年第4期1318-1329,共12页Huiqiong Deng Wenying Chen Lingyun Han Boyang Zhang Xun Luo Song Yao Hongwei Wang Yao Zhou Shuangchao Liu Xiao Li Shen 
financially supported by the National Natural Science Foundation of China(82060598,32260587);the Natural Science Foundation of Guizhou Province(QKH-J-ZK[2021]181);the Scientific Research Program of Guizhou Provincial Department of Education(QJJ[2023]019);the Science&Technology Program of Guizhou Province(QKHPTRC-CXTD[2022]014);the Excellent Youth Talents of Zunyi Medical University(17zy-006);the Innovation and Entrepreneurship Training Program for College Students of Guizhou Province(S202210661138);the Innovation and Entrepreneurship Training Program for College Students of Zunyi Medical University(ZYDC2021108)。
Foods and animal feeds frequently become contaminated with the nephrotoxic ochratoxin A(OTA).Our prior research has indicated that ursolic acid(UA),which is widely present in fruits and medicinal plants,has the potent...
关键词：Ochratoxin A Ursolic acid Endoplasmic reticulum(ER)stress ER-phagy ER-phagic flux Apoptosis 
Nootkatone suppresses TLR4/NF-κB/NLRP3 pathway to alleviate non-alcoholic fatty liver disease via modulating gut microbiota
《Food Science and Human Wellness》2025年第4期1398-1410,共13页Rongrong Fu Wenqing Xue Jingjie Liang Lechen Wang Min Zhang Jing Meng 
supported by grants from National Natural Science Foundation of China(82072709,81902441);Natural Science Foundation of Tianjin Municipal(23JCYBJC00850);China Postdoctoral Science Foundation(2022M712374);Tianjin“131”Innovative Talent Team Project(201926)。
Non-alcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases worldwide.Gut microbiota and its metabolites alteration are closely related to NAFLD.Nootkatone is an edible flavorant derived f...
关键词：Nootkatone Non-alcoholic fatty liver disease Hepatic inflammation TLR4/NF-κB/NLRP3 Gut microbiome 
Human amniotic epithelial cells alleviate ischemia-reperfusion injury of steatotic livers through mediating PAK1/AMPK-dependent autophagy
《Genes & Diseases》2025年第2期110-112,共3页Xun Qiu Hanzhi Xu Yawen Tan Jinying Li Zhoucheng Wang Zhengxing Lian Xuyong Wei Luyang Yu Kai Wang Xiao Xu 
supported by the National Key Research and Development Program of China (No.2021YFA1100503);Zhejiang Provincial Natural Science Foundation (China) (No.LY22H160048);Key Research&Development Program of Zhejiang Province (China) (No.2022C03108).
Hepatic steatosis is prevalent worldwide and is characterized as excessive lipid accumulation with/without inflammation and injury in the liver.Hepatic ischemia-reperfusion(HIR)injury commonly occurs in the process of...
关键词：ischemia REPERFUSION Hepatic 
Can industrial agglomeration alleviate energy poverty?Evidence from China
《Chinese Journal of Population,Resources and Environment》2025年第1期15-26,共12页Xiaomeng Zhao Yichuan Xie Qingzhe Jiang Jun Zhao 
sponsored by the National Social Science Fund of China[Grant No.23VMG006].
This study determines whether industrial agglomeration can solve energy poverty(ENPO)by applying a provincial dataset(2002-2019)to assess the potential effect of industrial agglomeration on ENPO.Additionally,this stud...
关键词：Energy poverty alleviation Industrial agglomeration Heterogeneous analysis Mechanism analysis China 
Microneedle-delivered biomimetic nanodecoys target type Ⅳ collagen and scavenge multiple cytokines to alleviate psoriatic inflammation
《Nano Research》2025年第3期401-416,共16页Fei Qu Jinying Qin Min Li Yuting Xia Yihui Wang Hongmei Liu Juan Tao Yijing Liu Jintao Zhu 
financially supported by the National Natural Science Foundation of China(No.52373138);the Fundamental Research Funds for the Central Universities(HUST:2023JYCXJJ052 and 2020kfyXJJS060);Shenzhen Science and Technology Program(No.CYJ20220530160603007).
The immunomodulatory efficacy of current psoriasis biological therapies is hindered by their limited ability to scavenge multiple cytokines,inefficient delivery to specific inflamed skin regions,and potential side eff...
关键词：nanodecoy MICRONEEDLE type IV collagen-targeting cytokines scavenging PSORIASIS 
Brassinosteroids alleviate wheat floret degeneration under low nitrogen stress by promoting the redistribution of sucrose from stems to spikes
《Journal of Integrative Agriculture》2025年第2期497-516,共20页Zimeng Liang Xidan Cao Rong Gao Nian Guo Yangyang Tang Vinay Nangia Yang Liu 
supported by the Key Research and Development Program of Shaanxi,China(2021NY-083);the National Natural Science Foundation of China(31871567)。
The trade-off between yield and environmental effects caused by nitrogen fertilizer application is an important issue in wheat production.A reduction in fertile florets is one of the main reasons for the lower yields ...
关键词：BRASSINOSTEROIDS fertile florets nitrogen application rate sucrose metabolism WHEAT 
Can the Environmental Credit Evaluation Policy Alleviate the Overcapacity of Heavily Polluting Enterprises?
《China & World Economy》2025年第1期162-194,共33页Chuanwang Sun Jiahui Chen 
support from the Major Program of the National Social Science Foundation of China(No.21&ZD109).
Addressing pollution caused by economic development,especially the overcapacity of polluting enterprises,is crucial for promoting sustainable economic growth.Targeted environmental policies are essential for strengthe...
关键词：capacity utilization environmental credit evaluation policy time-varying difference-in-difference-in-differences model heavily polluting enterprises OVERCAPACITY 
Cerium Oxide Nanoparticles Alleviate Enhanced UV-B Radiation-Induced Stress in Wheat Seedling Roots by Regulating Reactive Oxygen Species
《Phyton-International Journal of Experimental Botany》2025年第2期455-479,共25页Cheng Sun Chen Zhao Guohua Wang Qianwen Mao Rong Han 
supported by Graduate Innovation Project of Shanxi Normal University(Grant No.2021Y443).
Enhanced UV-B radiation represents a major environmental factor impacting global cereal production.Researchers have explored various approaches to reduce the detrimental impact of UV-B radiation on crops.Recently,engi...
关键词：Cerium oxide nanoparticles UV-B stress ROS scavenging transcriptomics analysis 
Selective embolization can effectively alleviate bleeding symptoms in patients with anorectal hemangioma
《World Journal of Gastrointestinal Surgery》2025年第1期304-306,共3页Ping-Hua Wen Bing Hu 
In this manuscript,I comment on the article by Pospisilova et al published in the recent issue of the journal,in which selective embolization was used to treat anorectal hemangioma,a rare disease causing lower gastroi...
关键词：Gastrointestinal hemangioma Anorectal hemangioma Treatment Surgery Endoscopic therapy MEDICATION 
Bletilla striata polysaccharides alleviate metabolic dysfunctionassociatedsteatotic liver disease through enhancing hepatocyteRelA/HNF1αsignal
《World Journal of Gastroenterology》2025年第4期88-122,共35页Yi-Huai He Li-Li Ou Jin-Lian Jiang Yun-Fen Chen Aikedaimu Abudukeremu Yuan Xue Mao-Yuan Mu Wei-Wei Zhong De-Lin Xu Xuan-Yu Meng Ya-Qun Guan 
National Natural Science Foundation of China,No.32260089;Science and Technology Research Foundation of Guizhou Province,No.QKHJC-ZK(2022)YB642;Science and Technology Research Foundation of Hubei Province,No.2022BCE030;Science and Technology Research Foundation of Changzhou City,No.CE20225040;Science and Technology Research Foundation of Zunyi City,No.ZSKHHZ(2022)344 and No.ZSKHHZ(2022)360;WBE Liver Fibrosis Foundation,No.CFHPC2025028.
BACKGROUND Bletilla striata polysaccharides(BSP)have antioxidant,immune regulation,and anti-fibrotic activities.However,the therapeutic effect and mechanisms underlying the action of BSP in metabolic dysfunction-assoc...
关键词：Bletilla striata polysaccharides Metabolic dysfunction-associated steatotic liver disease Nuclear factor kappa B p65/hepatocyte nuclear factor-1 alpha signaling Endoplasmic reticulum stress Oxidative stress Lipid metabolism reprogramming 
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