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CELL-FREE: 作品数：148被引量：425H指数：12; 导出分析报告; 相关作者：冉静学孙强李秀军郭晓东侯朝晖更多>>; 相关机构：哈尔滨工业大学中国航天科工集团第四研究院北京机电工程总体设计部中央民族大学凯迪迪爱通信技术有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells被引量：1: 《Neural Regeneration Research》2025年第1期277-290,共14页Meng Cong Jing-Jing Hu Yan Yu Xiao-Li Li Xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu Xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi; supported by the National Natural Science Foundation of China,No.31870977(to HYS);the National Key Technologies Research and Development Program of China,No.2017YFA0104700(to FD);2022 Jiangsu Funding Program for Excellent Postdoctoral Talent(to MC);Priority Academic Program Development of Jiangsu Higher Education Institutions[PAPD];the Major Project of Basic Science(Natural Science)Research in Higher Education Institutions of Jiangsu Province,No.22KJA180001(to QRH)。; Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve repair.Cell-based therapy can enhance peripheral nerve rep...; 关键词：AXOTOMY cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

Tumor derived cell-free nucleic acid upregulates programmed death-ligand 1 expression in neutrophil via intracellular Toll-like receptor signaling: 《Cancer Communications》2025年第1期4-8,共5页Suguru Saito Duo-Yao Cao Tomohiro Shibata Yan Liu Aoi Otagiri-Hoshi Xiaojiang Cui Kenneth E.Bernstein; supported by the National Institutes of Health grants(R01AI164519,2R01CA151610,R21CA280458);American Heart Association’s Career Development award(23CDA1052548);U.S.Department of Defense(W81XWH-18-1-0067)and the Glazer Foundation.; Neutrophils are innate immune cells that function predominantly against pathogens,while recent studies have revealed additional crucial roles in various diseases,including cancers[1–3].For instance,neutrophils expres...; 关键词：DEATH diseases programmed

Neural stem cell-derived exosomes:a cell-free transplant for potential cure of neurological diseases: 《BIOCELL》2024年第10期1405-1418,共14页JIAJUN HUANG WEI WANG WENTONG LIN HENGSEN CAI ZHIHAN ZHU WAQAS AHMED QIANKUN ZHANG JIALE LIU YIFAN ZHANG RONG LI ZHINUO LI AHSAN ALI KHAN DENG LU YONG HU LUKUI CHEN; Degeneration and death of nerve cells are inevitable with the occurrence and progression of nervous system disorders.Researchers transplanted neural stem cells into relevant areas,trying to solve the difficulty of neu...; 关键词：Stem cells EXOSOMES Nervous system diseases Neural regeneration Neural restoration Cell-free therapy

Drainage of ascites in cirrhosis: 《World Journal of Hepatology》2024年第9期1245-1257,共13页Jia-Xing Yang Yue-Ming Peng Hao-Tian Zeng Xi-Min Lin Zheng-Lei Xu; Supported by Sanming Project of Medicine in Shenzhen,No.SZSM202211029.; For cirrhotic refractory ascites,diuretics combined with albumin and vasoactive drugs are the first-line choice for ascites management.However,their therapeutic effects are limited,and most refractory ascites do not r...; 关键词：Liver cirrhosis ascites Large-volume paracentesis Transjugular intrahepatic portosystemic shunt Peritoneovenous shunt Automated low-flow ascites pump Cell-free and concentrated ascites reinfusion therapy Peritoneal catheter drainage

Proteomics of cell-free breast cancer scaffolds identify clinically relevant imprinted proteins and cancer-progressing properties: 《Cancer Communications》2024年第6期695-699,共5页Anna Gustafsson Emma Jonasson Anders Stalberg Goan Landberg; supported by grants from The Swedish Research Council(2019-01273 and 2021-01008);Sweden’s Innovation Agency(2017-03737);Swedish Cancer Foundation(22-2214 and 22-2080);the Swedish state under the agreement between the Swedish government and county councils,the ALF-agreement(965065 and 965580);BioCARE National Strategic Research Program at University of Gothenburg,Region Västra Götaland,The Sjöberg Foundation,Assar Gabrielssons Research Founda-tion,Stiftelsen Sigurd och Elsa Goljes Minne,and Kungliga och Hvitfeldtska Stiftelsen.; The composition of the extracellular tumor microenvironment(TME)has not been fully delineated,limiting the understanding of general cancer-progressing properties within the cancer niche.The interplay and dynamics betw...; 关键词：CANCER clinically BREAST

Circulating cell-free mtDNA as a new biomarker for cancer detection and management: 《Cancer Biology & Medicine》2024年第2期105-110,共6页Fan Peng Siyuan Wang Zehui Feng Kaixiang Zhou Huanqin Zhang Xu Guo Jinliang Xing Yang Liu; the National Natural Science Foundation of China(Grant No.81830070)。; Cancer is a major cause of death worldwide,and was responsible for 19.29 million new cases and 9.96 million deaths in 2020 alone.The total number of patients with cancer worldwide is estimated to reach 28 million by 2...; 关键词：CANCER CANCER DEATH

Mesenchymal stem cell-derived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration被引量：2: 《Neural Regeneration Research》2024年第1期49-54,共6页Ye Xiong Asim Mahmood Michael Chopp; supported by Notional Institutes of Health Grant,No.1R01NS100710-01A1(to YX)。; Traumatic brain injury is a serious and complex neurological condition that affects millions of people worldwide.Despite significant advancements in the field of medicine,effective treatments for traumatic brain injur...; 关键词：biomarkers extracellular vesicles functional outcome mesenchymal stem/stromal cells NEUROINFLAMMATION NEUROPLASTICITY NEUROPROTECTION traumatic brain injury

Method for the extraction of circulating nucleic acids based on MOF reveals cell-free RNA signatures in liver cancer: 《National Science Review》2024年第1期89-101,共13页Yuqing Sun Haixin Yu Shaoqing Han Ruoxi Ran Ying Yang Yongling Tang Yuhao Wang Wenhao Zhang Heng Tang Boqiao Fu Boshi Fu Xiaocheng Weng Song-Mei Liu Hexiang Deng Shuang Peng Xiang Zhou; financially supported by the National Natural Science Foundation of China (92153303, 21721005 and 91940000to X.Z.;81772276 and 81902141 to S.L.);the National Science Foundation for Young Scientists of China (21907078 to S.P.);Hubei Provincial Innovation Group (2019CFA018 to S.L.)。; Cell-free RNA(cf RNA) allows assessment of health, status, and phenotype of a variety of human organs and is a potential biomarker to non-invasively diagnose numerous diseases. Nevertheless, there is a lack of highly ...; 关键词：MOF circulating cell-free RNA biomarker liver cancer diagnosis

Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy: 《World Journal of Stem Cells》2024年第1期7-18,共12页Vitale Miceli; Mesenchymal stromal/stem cells(MSCs)have garnered significant attention in the field of regenerative medicine due to their remarkable therapeutic potential.MSCs play a pivotal role in maintaining tissue homeostasis an...; 关键词：Mesenchymal stromal/stem cells Therapeutic properties Paracrine effects Cell priming Cell-free therapies Regenerative medicine

Human pluripotent stem cell-derived extracellular vesicles:From now to the future: 《World Journal of Stem Cells》2023年第5期453-465,共13页Bruno Moises de Matos Marco Augusto Stimamiglio Alejandro Correa Anny Waloski Robert; Extracellular vesicles(EVs)are nanometric particles that enclose cell-derived bioactive molecules in a lipid bilayer and serve as intercellular communication tools.Accordingly,in various biological contexts,EVs are re...; 关键词：Pluripotent stem cells Extracellular vesicles EXOSOME Cell-free therapy

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