OSTEOPOROTIC

作品数：76被引量：346H指数：11
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相关作者：吴子祥张波李建磊韩维奇蒋伟宇更多>>
相关机构：南方医科大学第三附属医院温州医科大学泗洪县人民医院成都军区总医院更多>>
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Electrospun naringin-loaded microsphere/sucrose acetate isobutyrate system promotes macrophage polarization toward M2 and facilitates osteoporotic bone defect repair被引量：4
《Regenerative Biomaterials》2023年第1期470-485,共16页Jihong Li Jinlin Song Di Meng Yin Yi Ting Zhang Yu Shu Xiaohong Wu 
support from the National Natural Science Foundation of China(No.81970914).
Repairing osteoporotic bone defects is still a major clinical challenge.Recent studies have revealed that immune response is also essential in osteogenesis.The intrinsic inflammatory response of the host,especially th...
关键词：electrospun microspheres macrophage polarization Ng-m-SAIB osteoporotic bone defects 
Selenium-modified bone cement promotes osteoporotic bone defect repair in ovariectomized rats by restoring GPx1-mediated mitochondrial antioxidant functions被引量：1
《Regenerative Biomaterials》2023年第1期533-548,共16页Quan Zhou Weikai Chen Chao Gu Hao Liu Xiayu Hu Lei Deng Wei He Yong Xu Xuesong Zhu Huilin Yang Xi Chen Fan He Tao Liu 
supported by the National Natural Science Foundation of China(82072476,82072410);Natural Science Foundation of Jiangsu Province(BK20220046);Major Science and Technology Project of Changzhou Health Commission(ZD202001);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Key Laboratory of Orthopaedics of Suzhou(SZS2022017).
Over-accumulation of reactive oxygen species(ROS)causes mitochondrial dysfunction and impairs the osteogenic potential of bone marrow-derived mesenchymal stem cells(BMMSCs).Selenium(Se)protects BMMSCs from oxidative s...
关键词：sodium selenite OSTEOPOROSIS GPx1 mitochondrial function bone cement 
Functionalized TiCu/TiCuN coating promotes osteoporotic fracture healing by upregulating the Wnt/β-catenin pathway
《Regenerative Biomaterials》2023年第1期126-139,共14页Jia Tan Ling Ren Kai Xie Lei Wang Wenbo Jiang Yu Guo Yongqiang Hao 
supported by the National Natural Science Foundation of China[81972058 and 81902194];the Science and Technology Commission of Shanghai Municipality[22YF1422900 and 21002411200];the Shanghai Municipal Key Clinical Specialty,China[shslczdzk06701];Huangpu District Industrial Support Fund[XK2020009];the National Facility for Translational Medicine(Shanghai),China[TMSZ-2020-207];the Shanghai Engineering Research Center of Orthopedic Innovative Instruments and Personalized Medicine Instruments and Personalized Medicine[19DZ2250200].
Osteoporosis results in decreased bone mass and insufficient osteogenic function.Existing titanium alloy implants have insufficient osteoinductivity and delayed/incomplete fracture union can occur when used to treat o...
关键词：nitride-titanium-copper orthopaedic implant OSTEOGENESIS OSTEOINTEGRATION osteoporotic fractures 
Repair calvarial defect of osteoporotic rats by berberine functionalized porous calcium phosphate scaffold被引量：7
《Regenerative Biomaterials》2021年第3期84-93,共10页Dahao Wang Peng Zhang Xifan Mei Zhenhua Chen 
This work was supported by National Natural Science Foundation of China(No.81771987,82072076,82072165 and 81871556);Young Top Talents in Xing Liao Talents Program of Liaoning Province(XLYC1807183).
In this article,we propose a simple scheme of using berberine(BBR)to modify porous calcium phosphate ceramics(named PCPC).These BBR molecules regulate the crystallization of hydroxyapatite nanorods on PCPC.We found th...
关键词：BERBERINE porous ceramics BMSCS OSTEOPOROSIS 
Tuning osteoporotic macrophage responses to favour regeneration by Cu-bearing titanium alloy in Porphyromonas gingivalis lipopolysaccharide-induced microenvironments被引量：2
《Regenerative Biomaterials》2021年第1期102-111,共10页Xiongcheng Xu Yanjin Lu Ling Zhou Mengjiao He Jin Zhuo Quan Zhong Kai Luo Jinxin Lin 
This study was supported by National Natural Science Foundation of China(Grant No.81870766,51801198);the Science Foundation of Fujian Province(Grant No.2017J01805);Joint Funds for the Innovation of Sciences and Technology,Fujian Province(Grant No.2016Y9023);Startup Fund for scientific research,Fujian Medical University(Grant No.2019QH2041).
Guided bone regeneration in inflammatory microenvironments of osteoporotic patients with large alve-olar bone defects remains a great challenge.Macrophages are necessary for alveolar bone regeneration via their polari...
关键词：copper OSTEOPOROSIS MACROPHAGES inflammation 
Locking system strengthened by biomimetic mineralized collagen putty for the treatment of osteoporotic proximal humeral fractures被引量：5
《Regenerative Biomaterials》2017年第5期289-294,共6页Cheng Peng Hai-Peng Wang Jia-Hua Yan Tian-Xi Song 
This work was partially supported by Shanghai Municipal Health Bureau(No.2011239);the National Science and Technology Supporting Program of China(No.2012BAI17B02).
The current study is to observe the effect of the locking system strengthened by biomimetic mineralized collagen putty for the treatment of senile proximal humeral osteoporotic fractures.From January 2012 to December ...
关键词：mineralized collagen putty OSTEOPOROSIS proximal humeral fracture locking system 
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