EPITOPES

作品数：96被引量：141H指数：7
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相关领域：医药卫生更多>>
相关作者：郭礼和费俭夏国宏邢力叶欣更多>>
相关机构：中国科学院上海生命科学研究院郑州大学南昌大学广州血液中心更多>>
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  • 学科=医药卫生—病原生物学x
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Neutralization of SARS-CoV-2 infection by antibodies targeting diverse epitopes
《Genes & Diseases》2024年第4期134-137,共4页Shusheng Wang Yunji Liao Kaiyong Yang Hang Ma Zhangyi Song Haiqiu Huang Li Zhang Ailing Wang Lei Han Jiawei Zhang Hui Chen Haiyang Yin Yantin Bian Hua Jiang Xiaodong Xiao Yueqing Xie Yunsheng Yuan Jianwei Zhu 
the National Natural Science Foundation of China(No.81773621,82073751 to JZ);the National Science and Technology Major Project"Key New Drug Creation and Manufacturing Program"of China(No.2019ZX09732001-019 to JZ);the Key R&D Supporting Program(Special support for developing medicine for infectious diseases)from the Administration of Chinese and Singapore Tianjin Eco-city to Jecho Biopharmaceuticals Ltd.Co.,Zhejiang University special CoVID-19 grant 2020XGZX099;Shanghai Jiao Tong University"Crossing Medical and Engineering"grant 20X190020003 to JZ.
The CoVID-19 pandemic that started in late 2019 is sweeping through the world,posing historic challenges to global health,and disrupting social and economic lives.Previous and recent studies indicate that monoclonal a...
关键词：ANTIBODIES inhibited MONOCLONAL 
An antibody cocktail with broadened mutational resistance and effective protection against SARS-CoV-2
《Science China(Life Sciences)》2023年第1期165-179,共15页Chunyun Sun Hang Chi Fei Yuan Jing Li Ji Yang Aihua Zheng Fei Wang Lingling Sun Yanjing Zhang Ping Hu Lihua Jiao Yongqiang Deng Liangzhi Xie 
supported by the National Key Research and Development Project of China(2021YEF0201700)。
Neutralizing antibodies have been proven to be highly effective in treating mild and moderate COVID-19 patients,but continuous emergence of SARS-CoV-2 variants poses significant challenges.Antibody cocktail treatments...
关键词：SARS-CoV-2 COVID-19 EPITOPES antibody cocktail mutational escape 
History,epidemiology,vaccine and transmission of coronavirus disease 2019 (COVID-19):a quick review
《Life Research》2021年第3期9-19,共11页Rabia Altaf Asra Iftikhar Rabia Haq Bushra Zahoor Muhammad Zaini Asmawi Mohamed Khadeer Ahamed Basheer 
Coronavirus belonging to family Coronaviridae is a large group of viruses causing respiratory and gastrointestinal diseases.The outbreak of 2019-novel coronavirus has created panic in the whole world after being trans...
关键词：PANDEMIC Severe acute respiratory syndrome coronavirus-2 Social distance Respiratory illness EPITOPES S-glycoprotein 
Potential epitopes and mutation characteristics of 2019 novel coronavirus spike protein
《China Medical Abstracts(Internal Medicine)》2021年第1期23-24,共2页LI Hu 
Objective To predict the epitopes of the spike protein of 2019 novel coronavirus(2019-nCoV)and to analyze the mutation characteristics of this protein.Methods The gene sequences of 2019-nCoV was downloaded from GenBan...
关键词：CHARACTERISTICS IMMUNE SPIKE 
Structural biology oriented predicative analysis of immunogenic epitopes on SARS-CoV-2 viral sequence by variable algorithms
《Asian Pacific Journal of Tropical Medicine》2020年第6期283-284,共2页Dhanasekaran Sivaraman 
Epitopes are small segmented antigenic peptides that are able to elicit the immune response by recognizing B and T-cells.In the present scenario,knowledge of immunogenic epitopes specific to severe acute respiratory s...
关键词：ACUTE VACCINE RESPIRATORY 
Human leukemia antigen-A0201-restricted epitopes of humanendogenous retrovirus W family envelope(HERV-W env)inducestrong cytotoxic T lymphocyte responses被引量：4
《Virologica Sinica》2017年第4期280-289,共10页Xiaoning Tu Shan Li Lijuan Zhao Ran Xiao Xiuling Wang Fan Zhu 
supported by grants from the National Natural Sciences Foundation of China(no.31470264,no.81271820,no.30870789 and no.30300117);the Key Program of the Natural Science Foundation of Hubei Province of China(no.2014CFA078);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),USA(no.06R-1366),for Dr.F Zhu;the Scientific Innovation Team Project of Hubei Province of China(no.2015CFA009)
Human endogenous retrovirus W family(HERV-W) envelope(env) has been reported to be related to several human diseases, including autoimmune disorders, and it could activate innate immunity.However, there are no reports...
关键词：HUMAN endogenous RETROVIRUS W (HERV-W) ENV peptide HLA CTL 
Mapping epitopes of human papillomavirus type 16 L1 protein with a phage display epitope library
《Chinese Medical Journal》1998年第3期11-11,共1页刘天菊 司履生 王一理 孙向乐 杨居祥 耿宜萍 
Abstract Objective It has been well accepted that human papillomavirus type 16 (HPV16) is associated with human cervical cancer and HPV16 L1 protein could induce both humoral and cellular immune responses. The obje...
A modified hepatitis B surface antigen carrying both preS1 and preS2 epitopes
《Science China(Life Sciences)》1998年第1期56-63,共8页惠静毅 李光地 孔玉英 汪垣 
ProjectsupportedbytheNational"863"HighTechnologyFoundationofChina
The DNA fragments coding for preS2(120 146) and preS1(21 47) amplified by PCR were fused to both 5′ and 3′ ends of S gene at the position of amino acid 223. The fusion gene was placed downstream of the promoter P7.5...
关键词：HEPATITIS B surface ANTIGEN (HBsAg) PRES1 and PRES2 EPITOPES fusion protein particle recombi nant VACCINIA virus. 
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