EPITOPES

作品数：96被引量：141H指数：7
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相关领域：医药卫生更多>>
相关作者：郭礼和费俭夏国宏邢力叶欣更多>>
相关机构：中国科学院上海生命科学研究院郑州大学南昌大学广州血液中心更多>>
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  • 学科=医药卫生—肿瘤x
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Novel Immunogenic Epitopes in the NaPi-IIb Protein: Production of Monospecific Antibodies Using Synthetic Peptides Outlined on Isoform Specific Regions of the Type IIb Sodium-Dependent Phosphate Transporter (NaPi-IIb)
《Journal of Cancer Therapy》2016年第2期129-151,共23页Ângela Alice Amadeu Megale Jorge Mário da Costa Ferreira Júnior Letícia Batista Azevedo Rangel Maria Del Pilar Estevez Diz Max Senna Mano Paulo Marcelo Gehm Hoff Priscila Hess Lopes Roberto Jun Arai Wilmar Dias da Silva 
NaPi-IIb is a multiple passage protein membrane which is primarily responsible for phosphate uptake in the kidney and in the small intestine. Beyond its physiological functions, their involvement with carcinogenesis w...
关键词：NaPi2b Peptides ANTIBODIES Ovarian Cancer 
Genome-wide comparison inferred the origin and evolution of B-cell epitopes on the proteins of human influenza A virus
《Health》2012年第10期946-954,共9页Edgar E. Lara-Ramírez Aldo Segura-Cabrera Ma. Isabel Salazar Mario A. Rodríguez-Pérez Xianwu Guo 
The novel strain H1N1 caused the outbreak of first pandemic influenza in 21 century. Now it is a common component of current seasonal influenza viruses. The recent transmission and plentiful genome sequences available...
关键词：INFLUENZA A Virus H1N1 PANDEMIC EPITOPES Genome COMPARISON 
Improving <i>in Silico</i>Prediction of Epitope Vaccine Candidates by Union and Intersection of Single Predictors
《World Journal of Vaccines》2011年第2期15-22,共8页Ivan Dimitrov Darren R. Flower Irini Doytchinova 
The in silico prediction of peptide binding affinities to MHC proteins is a very important first step in the process of epi-tope-based vaccine design and development. Five MHC class II binding prediction servers were ...
关键词：MHC Class II Binders T-CELL EPITOPES HLA-DRB1 Alelles 
Generation and Characterization of a Panel of Monoclonal Antibodies Against Distinct Epitopes of Human CD146
《生物物理学报》2009年第S1期231-232,共2页Ping Wang1, Xiyun Yan.National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China 
CD146 (MUC18, Mel-CAM/MCAM) is a transmembrane protein, originally identified as a biomarker of melanoma, and plays an important role in cancer invasion and metastasis.
关键词：HUMAN CD146 antibody different EPITOPES 
Bioinformatics analysis and characteristics of envelop glycoprotein E epitopes of dengue virus被引量：1
《Journal of Biomedical Science and Engineering》2009年第2期123-127,共5页Hua Zhong Wei Zhao Liang Peng Shan-Feng Li Hong Cao 
The major envelope glycoprotein E of dengue (DEN) virus plays a central role in the biology of flaviviruses. It is capable of inducing a protective immune response in vivo and responsible for the viral binding to the ...
关键词：DENGUE VIRUS GLYCOPROTEIN E EPITOPE BIOINFORMATICS 
Identification of Melanoma-specific Peptide Epitopes by HLA-A2.1-restricted Cytotoxic T Lymphocytes被引量：1
《Acta Biochimica et Biophysica Sinica》2006年第2期110-118,共9页Hai-Liang GE Ying WANG Shu-Jun WANG Yong ZHANG 
This work was supported by the grants from the National Science Foundation of China （No. 30371598） and Shanghai Leading Academic Discipline Project （No. T0206）
HLA-A2.1-associated peptides, extracted from human melanoma cells, were used to study epitopes for melanoma-specific HLA-A2.1-restricted cytotoxic T lymphocytes （CTLs） by epitope reconstitution, active peptide seque...
关键词：melanoma cell line cytotoxic T lymphocyte tumor antigenic peptide HLA-A2.1-associated peptide 
Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach被引量：5
《中国生物学文摘》2006年第1期52-52,共1页Cansheng Zhu Xuesong Liu Jiannan Feng Wei Zhang Beifen Shen Weiming Ou＇yang Yunxin Cao Boquan Jin 
关键词：瘤坏死因子 单克隆抗体 压制活性 TNF表位 分子图形 突变型蛋白质 
Combined Transfection with EBV-Specific Epitopes and HLA-A2 genes is More Effective than Separate Transfection in Promoting CTL Lysis against Nasopharyngeal Carcinoma
《Cellular & Molecular Immunology》2004年第3期229-234,共6页WeijunDing ChoylenFong 
To augment specific cytotoxic T lymphocyte(CTL)lysis is a promising strategy for cancer therapy,in this study, we examined the boosting effect of CTLs upon autologous lymphoblastoid B cell lines(LCLs)transfected with ...
关键词：NPC LMP2 LCL HLA-A2 CTL 
ANALYSIS ON EPITOPES OF IGM WITH MONOCLONAL ANTI-ISOTYPIC AND ANTI-IDIOTYPIC ANTIBODIES AGAINST IgM FROM B-CLL
《Chinese Journal of Cancer Research》1992年第4期36-42,共7页沈关心 苏娜 王晓林 朱慧芬 张悦 秦立轩 
A double antibodies additivity ELISA test was employed to identify the epltopes which can be recognized by monoclonal antibodies (McAbs) against IgM from B chronic lymphocyte leukemia (B-CLL). The computer grouping pr...
关键词：antigen epltope  antibody  monoclonal additivity ELISA test  B chronic lymphocyte leukemia  computer grouping programme analysis. 
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