POSTCONDITIONING

作品数：38被引量：305H指数：10
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相关领域：医药卫生更多>>
相关作者：薛枫蒋文平李勋韩莲花蒋廷波更多>>
相关机构：苏州大学哈尔滨医科大学天津市第三中心医院首都医科大学更多>>
相关期刊：《中国急救医学》《Chinese Journal of Traumatology》《Acta Pharmacologica Sinica》《中国现代医学杂志》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金山西省自然科学基金更多>>
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Pim-1 Kinase Regulating Dynamics Related Protein 1 Mediates Sevoflurane Postconditioning-induced Cardioprotection被引量：7
《Chinese Medical Journal》2017年第3期309-317,共9页Jin-Dong Liu Hui-Juan Chen Da-Liang Wang Hui Wang Qian Deng 
Background： It is well documented that sevoflurane postconditioning （SP） has a significant myocardial protection effect. However, the mechanisms underlying SP are still unclear. In the present study, we investigate...
关键词：CARDIOPROTECTION Ischemia-reperfusion Injury MITOCHONDRIA PIM-1 POSTCONDITIONING SEVOFLURANE 
Post-conditioning with gradually increased reperfusion provides better cardioprotection in rats被引量：6
《World Journal of Emergency Medicine》2014年第2期128-134,共7页Guo-ming Zhang Yu Wang Tian-de Li Xiao-yan Li Shao-ping Su Yuan-yuan Sun Xiu-hua Liu 
supported by grants from the National Science Foundation of China(30740080);Dean fund of the General Hospital of Jinan Military Command(2011Q08)
BACKGROUND: Rapid and complete reperfusion has been widely adopted in the treatment of patients with acute myocardial infarction(AMI), but this process sometimes can cause severe reperfusion injury. This study aimed t...
关键词：Ischemia-reperfusion injury POSTCONDITIONING Apoptosis 
Restoration of autophagic flux in myocardial tissues is required for cardioprotection of sevoflurane postconditioning in rats被引量：27
《Acta Pharmacologica Sinica》2014年第6期758-769,共12页Yu-lin ZHANG 
Acknowledgements This work was supported by the National Natural Science Foundation of China （Grant No 81070098 and 81200109）.
Aim： Sevoflurane postconditioning （SpostC） has been shown to protect the heart from ischemia-reperfusion （I/R） injury. In this study, we examined whether SpostC affected autophagic flux in myocardial tissues tha...
关键词：SEVOFLURANE inhalation anesthetics POSTCONDITIONING heart ischemia-reperfusion injury CARDIOPROTECTION AUTOPHAGY CHLOROQUINE 
Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/ reperfusion injury被引量：9
《Acta Pharmacologica Sinica》2011年第6期824-833,共10页Sunny Yang XIANG Linda L YE Li-lu Marie DUAN Li-hui LIU Zhi-dong GE John A AUCHAMPACH Garrett J GROSS Dayue Darrel DUAN 
Aim： To further characterize the functional role of cystic fibrosis transmembrane conductance regulator （CFTR） in early and late （second window） ischemic preconditioning （IPC）- and postconditioning （POC）-medi...
关键词：ISCHEMIA PRECONDITIONING POSTCONDITIONING apoptosis cystic fibrosis transmembrane conductance regulator （CFTR） 
Sevoflurane postconditioning reduces myocardial reperfusion injury in rat isolated hearts via activation of PI3K/Akt signaling and modulation of Bcl-2 family proteins被引量：36
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2010年第9期661-672,共12页Li-na YU Jing YU Feng-jiang ZHANG Mei-juan YANG Ting-ting DING Jun-kuan WANG Wei HE Tao FANG Gang CHEN Min YAN 
supported by the National Natural Science Foundation of China (No. 30772090);the Natural Science Foundation of Zhejiang Province (Nos. Y204141 and R2090259);the Foundation from Science and Technology Department of Zhejiang Province (No. 2007R10034);the Foundation from the Health Bureau of Zhejiang Province (No. 2007QN007),China
Sevoflurane postconditioning reduces myocardial infarct size.The objective of this study was to examine the role of the phosphatidylinositol-3-kinase(PI3K)/Akt pathway in anesthetic postconditioning and to determine w...
关键词：SEVOFLURANE POSTCONDITIONING CARDIOPROTECTION Akt Bcl-2 BAD 
Hyperlipidemia does not prevent the cardioprotection by postconditioning against myocardial ischemia/reperfusion injury and the involvement of hypoxia inducible factor-1α upregulation被引量：9
《Acta Biochimica et Biophysica Sinica》2009年第9期745-753,共9页Huanxin Zhao Yehong Wang Ye Wu Xiaoyu Li Guangzhao Yang Xiurui Ma Rongmi Zhao Huirong Liu 
This work was supported by the grants from the National Natural Science Foundation （No. 30572084 and 30700276） and Undergraduation Technological Innovation of Taiyuan City （08122085 to Huanxin Zhao）.
Hyperlipidemia is regarded as an independent risk factor in the development of ischemic heart disease, and it can increase the myocardial susceptibility to ischemia/reperfusion （I/R） injury, lschemic postconditioni...
关键词：HYPERLIPIDEMIA ischemic postconditioning myocardial infarction hypoxia inducible factor-1 
Cardioprotection Afforded by Norepinephrine-mediated Postconditioning in Isolated Rat Hearts
《South China Journal of Cardiology》2008年第3期143-149,共7页黄新华 李岱 张一帅 李年生 陈本美 彭军 李元建 
the grant from National Basic Research Program (937Program, No.2007CB512000, China)
Objectives Previous studies have demonstrated that endogenous norepinephrine （NE） plays an important role in the mediation of ischemic preconditioning. The present study is designed to determine whether NE is also i...
关键词：POSTCONDITIONING NOREPINEPHRINE CARDIOPROTECTION RAT 
Cardioprotection of sevoflurane postconditioning by activating extracellular signal-regulated kinase 1/2 in isolated rat hearts^1被引量：41
《Acta Pharmacologica Sinica》2008年第8期931-941,共11页Hong-tao CHEN Cheng-xiang YANG Heng LI Cheng-jing ZHANG Xian-jie WEN Jun ZHOU You-ling Fan Teng HUANG Yin-ming ZENG 
Aim： The activation of extracellular signal-regulated kinase （ERK）1/2 protects against ischemic-reperfusion injury. Whether ERK1/2 mediates the cardioprotection of sevoflurane postconditioning is unknown. We tested...
关键词：SEVOFLURANE POSTCONDITIONING extracellular signal-regulated protein kinase p70S6kinase MITOCHONDRIA cytochrome c ISCHEMIA-REPERFUSION 
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