EUKARYOTES

作品数：39被引量：113H指数：6
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相关领域：生物学更多>>
相关作者：张晓詹树萱张焱宗晖雷正玉更多>>
相关机构：湖北生态工程职业技术学院复旦大学中山大学中国科学院上海生命科学研究院更多>>
相关期刊：《Applied Mathematics》《Science China Earth Sciences》《Geoscience Frontiers》《Science China(Life Sciences)》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Unveiling an ancient whole-genome duplication event in Stentor, the model unicellular eukaryotes
《Science China(Life Sciences)》2025年第3期825-835,共11页Weibo Zheng Chao Li Zhaorui Zhou Xiao Chen Michael Lynch Ying Yan 
supported by the Science & Technology Innovation Project of Laoshan Laboratory(LSKJ202203203);the National Science Foundation of China (32270558);the National Institutes of Health Grant (R35-GM122566-01);the National Science Foundation (DEB-1927159, DBI-2119963);the Moore and Simons Foundations (735927);the Young Taishan Scholar Program of Shandong Province;the Project of Outstanding Young Innovative Team in Higher Education Institutions of Shandong Province (2023KJ038).
Whole-genome duplication(WGD)events are widespread across eukaryotes and have played a significant role in moulding the genetic architectures of diverse organisms.In the present study,the newly sequenced genome of a g...
关键词：genome complexity CILIATES whole-genome duplication Stentor 
Towards the first synthetic eukaryotic cell
《Biosafety and Health》2024年第6期376-382,共7页Wangyue Xu Yue Teng Sijie Zhou 
supported by the National Key Research and Development Program of China(2023YFA0913700);China Postdoctoral Science Foundation(2023 M732591);the Key R&D Program of Shandong Province,China(2022SFGC0102).
With the rapid advance in synthetic biology and the expanding field of synthetic genomics,the realization of a redesigned yeast genome has become an achievable milestone.Multiple eukaryotic chromosomes,meticulously de...
关键词：Synthetic biology Synthetic genomics EUKARYOTES 
An improved method for tubulin staining of ciliated eukaryotes
《Water Biology and Security》2024年第3期65-71,共7页Tingting Pan Jing Zhang Che Hu Guanxiong Yan Weiwei Qin Zixin Cheng Dongxia Yuan Fang Zhou Jie Xiong Wei Miao Chuanqi Jiang 
supported by the Third Xinjiang Scientific Expedition Program(2021xjkk0204,2021xjkk0604);Science&Technology Fundamental Resources Investigation Program(2022FY100400);Background Resources Survey in Shennongjia National Park(SNJNP2022008);Hubei Provincial Key Laboratory for Conservation Biology of Shennongjia Snub-nosed Monkeys(SNJGKL2022008);Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation,Beibu Gulf University(2020KA05).
Ciliated microeukaryotes(ciliates)are distinguished by their cilia,which are rich in tubulin.We developed a method for tubulin staining in ciliate cells that involves using live-cell tubulin-staining dyes instead of a...
关键词：CILIATE CILIUM Live-cell tubulin dye Tubulin staining 
Applications of genetic code expansion technology in eukaryotes
《Protein & Cell》2024年第5期331-363,共33页Qiao-ru Guo Yu J.Cao 
This work was supported by the National Key R&D Program of China(Nos.2019YFA0904200 and 2019YFA0906100);the National Natural Science Foundation of China(No.32171464);Shenzhen Science and Technology Innovation Program(JCYJ20180504165501371).
Unnatural amino acids(UAAs)have gained significant attention in protein engineering and drug development owing to their ability to introduce new chemical functionalities to proteins.In eukaryotes,genetic code expansio...
关键词：genetic code expansion unnatural amino acid EUKARYOTES basic research therapeutic applications 
Fanzors: Striking expansion of RNA-guided endonucleases to eukaryotes
《Cell Research》2024年第2期99-100,共2页Hui Yang Dinshaw J.Patel 
RNA-guided DNA endonucleases are broadly associated with and play critical roles in prokaryotic adaptive immunity-based CRISPR-Cas systems and IS200/605 family transposons.The Feng Zhang lab recently elucidated the ph...
关键词：PHYLOGENY mechanism thereby 
Protein post-translational modification by lysine succinylation:Biochemistry,biological implications,and therapeutic opportunities被引量：1
《Genes & Diseases》2023年第4期1242-1262,共21页Guo Zhao Junfeng Zhen Xinyuan Liu Jinshuai Guo Duanduan Li Jianping Xie Longxiang Xie 
supported by National Natural Science Foundation of China(No.82002172);Key Scientific Research Project Plan of Henan Province(No.20A180001);Innovation program of Henan university students(No.202110475033,20217003003).
Lysine succinylation(Ksuc)is a novel protein post-translational modification(PTM)wherein a succinyl group modifies a lysine residue.Ksuc leads to significant chemical and struc-tural changes to the modified protein.Re...
关键词：Disease EUKARYOTES Lysine succinylation Physiology PROKARYOTES Protein post-translational modification 
Bacterial and eukaryotic community interactions might contribute to shrimp culture pond soil ecosystem at different culture stages
《Soil Ecology Letters》2022年第2期119-130,共12页Renjun Zhou Hao Wang Dongdong Wei Shenzheng Zeng Dongwei Hou Shaoping Weng Jianguo He Zhijian Huang 
This work was financially supported by the China Agriculture Research System(CARS-48);China-ASEAN Maritime Cooperation Fund,China-ASEAN Center for Joint Research and Promotion of Marine Aquaculture Technology;Guangdong MEPP Fund(NO.GDOE(2019)A21);Key Research and Development Projects in Guangdong Province(2020B0202010009);Guangzhou Science Technology and Innovation Commission Project(201510010071);Guangdong Ocean and Fishery Bureau Project(20164200042090023).
Sedimentary bacterial and eukaryotic communities are major components of the aquatic ecosystem.Revealing the linkages between their community structure and interactions is crucial to understand the diversity and funct...
关键词：Sediment Shrimp culture Bacteria EUKARYOTES Microbial community 
Expanding Asgard members in the domain of Archaea sheds new light on the origin of eukaryotes
《Science China(Life Sciences)》2022年第4期818-829,共12页Ruize Xie Yinzhao Wang Danyue Huang Jialin Hou Liuyang Li Haining Hu Xiaoxiao Zhao Fengping Wang 
supported by the National Natural Science Foundation of China (91751205, 41921006, 41902313, 92051116);the China Ocean Mineral Resources R&D Association (COMRA) project (DY135-B2-12);the National Key Research and Development Project of China (2018YFC0310803);the Senior User Project of RV KEXUE (KEXUE2019GZ06)
The hypothesis that eukaryotes originated from within the domain Archaea has been strongly supported by recent phylogenomic analyses placing Heimdallarchaeota-Wukongarchaeota branch from the Asgard superphylum as the ...
关键词：Asgard archaea eukaryotic origin METAGENOME 
G-quadruplexes in genomes of viruses infecting eukaryotes or prokaryotes are under different selection pressures from hosts被引量：1
《Journal of Genetics and Genomics》2022年第1期20-29,共10页Zhen Li Sheng Hu Qian Fan Wang Hany IMohamed Guangfu Yang Zhen-Xia Chen Dengguo Wei 
supported by the National Natural Science Foundation of China(21732002,22077043,31672558,31871305,21907036);Opening Foundation of State Key Laboratory of Freshwater Ecology and Biotechnology,China(2020FB08);the Fundamental Research Funds for the(2662018PY021,2662019PY003,2662020PY001);Huazhong Agricultural University Scientific&Technological Self-innovation Foundation(2016RC011);HZAU-AGIS Cooperation Fund(SZYJY2021010)。
G-quadruplexes in viral genomes can be applied as the targets of antiviral therapies, which has attracted wide interest. However, it is still not clear whether the pervasive number of such elements in the viral world ...
关键词：G-QUADRUPLEX Selection pressure Database Evolution 
Synthetic polycistronic sequences in eukaryotes被引量：4
《Synthetic and Systems Biotechnology》2021年第4期254-261,共8页Xuekun Wang Mario Andrea Marchisio 
The need for co-ordinate,high-level,and stable expression of multiple genes is essential for the engineering of biosynthetic circuits and metabolic pathways.This work outlines the functionality and design of IRES-and ...
关键词：Synthetic biology 2A peptide IRES Polycistronic sequence 
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