supported by the RGC General Research Fund(17120720 to K.F.L.);the Professor PC Ho Research and Development Fund in Reproductive Medicine from the Department of Obstetrics and Gynecology,University of Hong Kong and Health and Medical Research Fund,Hong Kong(L.H.J.);a Conference and Research Committee grant from the University of Hong Kong(K.F.L.).
Endometrial stromal cell decidualization is a crucial step in endometrial remodeling during pregnancy.Decidualization is controlled by orchestrated ovarian hormones,followed by the activation of various downstream sig...
supported by the National Key R&D Program of China (2022YFC2702500 and 2021YFC2700302);National Natural Science Foundation of China (82288102).
This review aimed to summarize the major progress in maternal-fetal medicine achieved by Chinese scientists in recent years.PubMed was systematically searched from January 2020 to November 2023.Publications that repor...
supported by the National Key R&D Program of China(2019YFA0802600);the National Natural Science Foundation of China(32170863,31871512,and 31671199)to C.Z.Support was also received from grants from the Shanghai Commission of Science and Technology(17DZ2271100);Open Project of Shandong Provincial Key Laboratory of Reproductive Medicine(SDKL2017018).
Decidualization is the differentiation of endometrial stromal cells into secretory decidual stromal cells.Human decidualization involves some amount of signaling molecules and pathways as well as genetic reprogramming...
the National Key Technology R&D Program of China(2019YFC1005200 and 2019YFC1005201).
Background:Ovarian cysts are uncommon gestational complications.Because of high-level progesterone,ovarian endometriomas may undergo decidualization during pregnancy,manifesting as enlarging cysts with papillae and ri...
supported by the National Basic Research Program of China(2017YFC1001403);the National Nature Science Foundation of China(31970859,81630036,and 91542116);the Innovation-oriented Science and Technology Grant from the NHC Key Laboratory of Reproduction Regulation(CX2017-2);The Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine Supported by Ferring Pharmaceuticals and the Chinese Academy of Sciences(FIRMX200504);the funding for the Innovative Research Team of High-level Local Universities in Shanghai and a key laboratory program of the Education Commission of Shanghai Municipality(ZDSYS14005).
In early pregnancy,the decidua is populated by a large number of natural killer cells(NKs),most of which are CD56bright with a strong capacity to secrete cytokines,differing from peripheral and cord blood NK cells(pNK...
The work was supported by grant from the National Natural Science Foundation of China(81771587).
Decidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells,which is closely related to the occurrence of menstruation and establishment of pregnancy.Decidualiza...
the Natural Science Foundation of China(#31601206,31171436).
Embryo implantation and decidualization are crucial for successful pregnancy,which include multiple genes and signaling pathways,while the precise mechanism regarding embryo implantation and decidualization has yet to...
Supported by the National Natural Science Foundation of China(31472097)。
Lipopolysaccharide-binding protein(LBP)functions as an acute phase protein and plays a role in the innate immune response to bacterial challenge.To investigate the uterine expression of LBP during peri-implantation in...
Endometrial decidualization is one of the earlest changes by which the uterus adapts to pregnancy.During this period,the endometrium undergoes complex changes in its biochemistry,physiology,and function at various lev...
the National Natural Science Foundation of China(No.81701450).
Embryo implantation is a complicated physiological process tightly regulated by multiple biological molecules including growth factors.Transforming growth factor-betas(TGF-βs)and their most specific signal transducti...