DECIDUA

作品数：31被引量：112H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：石一复黄丽丽魏海明更多>>
相关机构：浙江大学医学院附属妇产科医院华中科技大学襄阳市中心医院中国科学技术大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Science China(Life Sciences)》《Reproductive and Developmental Medicine》《Genes & Diseases》更多>>
相关基金：国家自然科学基金更多>>
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Decreased expression of m6A demethylase ALKBH5 in decidua contributes to preeclampsia via m6A-CORIN-HuR pathway
《Genes & Diseases》2023年第3期650-653,共4页Jieqiong Yang Jing Tong Hongwanyu Li Shijian Lv Weiya Li Cong Zhang Wen Di 
supported by grants from the National Key R&D Program of China(No.2019YFA0802600)and NSFC(No.32170863,31871512)to C.Zhang;Support was also obtained from the Shanghai Commission of Science and Technology(No.17DZ2271100);Open Project of Shandong Provincial Key Laboratory of Reproductive Medicine(No.SDKL2017018),China.
Preeclampsia(PE)is a pregnancy-specific hypertensive disorder which poses a severe threat to maternal and fetal health.1 Defective decidualization may contribute to PE.^(2) N6-methyladenosine(m6A)is associated with va...
关键词：HYPERTENSIVE m6A pregnancy 
Single-cell sequencing analysis of the maternal-fetal interface
《Reproductive and Developmental Medicine》2023年第2期122-127,共6页Pei-Ru Wei Yi-Hua Yang 
supported by the Natural Science Foundation of Guangxi Zhuang Autonomous Region(2018GXNSFDA050017,2019GXNSFFA245013);the National Natural Science Foundation of China(81871172);the Guangxi Medical University Training Program for Distinguished Young Scholars.
The microenvironment at the maternal-fetal interface is optimized to facilitate the development and survival of the fetus during pregnancy.It involves a balance between cell populations and interactions of the fetal p...
关键词：Single-cell sequencing technology Maternal-fetal interface PLACENTA DECIDUA 
Decidualization and Related Pregnancy Complications
《Maternal-Fetal Medicine》2022年第1期24-35,共12页Jing Tong Shijian Lv Jieqiong Yang Hongwanyu Li Weiya Li Cong Zhang 
supported by the National Key R&D Program of China(2019YFA0802600);the National Natural Science Foundation of China(32170863,31871512,and 31671199)to C.Z.Support was also received from grants from the Shanghai Commission of Science and Technology(17DZ2271100);Open Project of Shandong Provincial Key Laboratory of Reproductive Medicine(SDKL2017018).
Decidualization is the differentiation of endometrial stromal cells into secretory decidual stromal cells.Human decidualization involves some amount of signaling molecules and pathways as well as genetic reprogramming...
关键词：DECIDUA DECIDUALIZATION Decidual stromal cells Endometrial stromal cells Pregnancy complications 
Biology and pathology of the uterine micro environ merit and its natural killer cells被引量：10
《Cellular & Molecular Immunology》2021年第9期2101-2113,共13页Fuyan Wang Anita Ellen Qualls Laia Marques-Fernandez Francesco Colucci 
Our lab is funded by the Wellcome Trust award 200841/Z/16/Z;FW was supported by grants from the National Natural Science Foundation of China 81501421.
Tissues are the new frontier of discoveries in immunology.Cells of the immune system are an integral part of tissue physiology and immunity.Determining how immune cells inhabit,housekeep,and defend gut,lung,brain,live...
关键词：Natural killer cells Uterine microenvironment Pregnancy DECIDUA uNK 
Maternal and fetal T cells in term pregnancy and preterm labor被引量：4
《Cellular & Molecular Immunology》2020年第7期693-704,共12页Derek Miller Meyer Gershater Rebecca Slutsky Roberto Romero Nardhy Gomez-Lopez 
This research was supported by the Wayne State University Perinatal Initiative in Maternal,Perinatal and Child Health and the Perinatology Research Branch,Division of Obstetrics and Maternal–Fetal Medicine,Division of Intramural Research,Eunice Kennedy Shriver National Institute of Child Health and Human Development,National Institutes of Health,U.S.Department of Health and Human Services(NICHD/NIH/DHHS);in part,with federal funds from NICHD/NIH/DHHS under Contract no.HHSN275201300006C.Dr.Romero has contributed to this work as part of his official duties as an employee of the United States Federal Government.
Pregnancy is a state of immunological balance during which the mother and the developing fetus must tolerate each other while maintaining sufficient immunocompetence to ward off potential threats.The site of closest c...
关键词：maternal-fetal interface DECIDUA amniotic fluid adaptive immunity PARTURITION 
The Mechanism of Swainsonine Causing Early Pregnancy Abnormal Decidualization and Inducing Abortion by Changing Glycosylation Modification
《Advances in Reproductive Sciences》2018年第3期70-101,共32页Yi Wang Xin Gao Ming Peng Yanfei You Fangyun Shi Yazhou Guo Baoyu Zhao Chenchen Wu 
Locoweed is a poisonous plant that severely harms the development of grass-land and animal husbandry throughout the world. Oxytropis and Astragalus are the Latin names for the poisonous plants commonly known as locowe...
关键词：SWAINSONINE GLYCOSYLATION Modification ABORTION DECIDUA Hormone Cell Apoptosis Endoplasmic Reticulum Stress 
Interaction between Kynurenine and Aryl Hydrocarbon Receptor in Regulating the Balance of T helper 17 Cells and Regulatory T-cells in Decidua during Early Gestation
《Reproductive and Developmental Medicine》2018年第1期8-14,共7页Tian-Tian Niu Shao-Liang Yang Ming-Qing Li Hai-Yan Wang 
supported by grants from the Natural Science Foundation of China(No.81373868).
Objective:To investigate whether kynurenine/aryl hydrocarbon receptor(AHR)affects the maternal-fetal tolerance by involving the differentiation of T helper 17(Th17)/regulatory T(Treg)cells,and to provide theoretical b...
关键词：ABORTION Aryl Hydrocarbon Receptor KYNURENINE Maternal-Fetal Tolerance Regulatory T-cells T helper 17 Cells 
Decidual natural killer cells and the immune microenvironment at the maternal-fetal interface被引量：16
《Science China(Life Sciences)》2016年第12期1224-1231,共8页Binqing Fu Haiming Wei 
supported by the Natural Science Foundation of China(91442202,81330071,81471527)
During early pregnancy, an orchestrated evolutionary maternal adaption toward tolerance of the semiallogeneic fetus is required to ensure decidualization and early embryo development. Remodeling of the immune system i...
关键词：NK cells DECIDUA fetal growth the immune microenvironment 
Decidual stromal cells recruit Th17 cells into decidua that promote proliferation and invasion of human trophoblast cells through secreting IL-17
《Science Foundation in China》2015年第2期20-20,共1页
With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,Prof.Li Dajin’s research group at the Institute of Obstetrics and Gynecology,Fudan University S...
关键词：INVASION RECRUIT MATERNAL fetal implicated IMMUNOLOGY cytokine inhibit AUTOIMMUNE rejection 
Expression and Influence of Galectin-3 on Missed Abortion被引量：1
《Journal of Reproduction and Contraception》2014年第4期227-234,共8页Li GAO Ai-hua FANG 
Objective To explore the influence of galectin-3 on missed abortion. Methods Forty cases of normal intrauterine early pregnancy were randomly divided into 2 groups： surgical abortion group （group A, n=20） and medic...
关键词：GALECTIN-3 early embryonic development VILLUS DECIDUA missed abortion 
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